Results 91 to 100 of about 2,646,419 (299)

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Epidemiology of Invasive Streptococcus pyogenes Infections in France in 2007 [PDF]

, 2011
A. Lepoutre, Alexandra Doloy, Philippe Bidet, Anne‐Laure Leblond, A Perrocheau, Édouard Bingen, Patrick Trieu‐Cuot, A. Bouvet, Claire Poyart, D Lévy-Brühl, the Microbiologists of the Epibac Network   +10 more
openalex   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

DHRS2 mediates cell growth inhibition induced by Trichothecin in nasopharyngeal carcinoma

Journal of Experimental & Clinical Cancer Research, 2019
Background Cancer is fundamentally a deregulation of cell growth and proliferation. Cancer cells often have perturbed metabolism that leads to the alteration of metabolic intermediates.
Xiangjian Luo, Namei Li, Xu Zhao, Chaoliang Liao, Runxin Ye, Can Cheng, Zhijie Xu, Jing Quan, Jikai Liu, Ya Cao   +9 more
doaj   +1 more source

Diagnostic accuracy, clinical utility and influence on decision‐making of a methylation urine biomarker test in the surveillance of non‐muscle‐invasive bladder cancer [PDF]

, 2019
David D‘Andrea, Francesco Soria, Sonja Zehetmayer, Kilian M. Gust, Stephan Korn, J. Alfred Witjes, Shahrokh F. Shariat   +6 more
openalex   +1 more source

Trophic network architecture of root-associated bacterial communities determines pathogen invasion and plant health

Nature Communications, 2015
Host-associated bacterial communities can function as an important line of defence against pathogens in animals and plants. Empirical evidence and theoretical predictions suggest that species-rich communities are more resistant to pathogen invasions. Yet,
Zhong Wei, Tianjie Yang, Ville‐Petri Friman, Yangchun Xu, Q. Shen, A. Jousset   +5 more
semanticscholar   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

The implications of signaling lipids in cancer metastasis

Experimental and Molecular Medicine, 2018
Cancer treatment: Targeting or Modifying lipids with signaling role Lipid molecules with cellular signaling roles are increasingly recognized as playing a role in cancer metastasis, the dangerous spread of cancer cells beyond a primary tumor, and these ...
Xiangjian Luo, Xu Zhao, Can Cheng, Namei Li, Ying Liu, Ya Cao   +5 more
doaj   +1 more source

Invasive bark beetle‐associated microbes degrade a host defensive monoterpene [PDF]

, 2015
Letian Xu, Min Lu, Jianghua Sun
openalex   +1 more source

Association between extramural vascular invasion and iodine quantification using dual-energy computed tomography of rectal cancer: a preliminary study

, 2022
Wei Gao, Yuqi Zhang, Yana Dou, Леи Жао, Hui Wu, Zhenxing Yang, Aishi Liu, Lu Zhu, Fene Hao   +8 more
openalex   +1 more source