Results 21 to 30 of about 99,152 (293)
Voltage Gated Lipid Ion Channels [PDF]
Biophysical Journal, 2013 10 pages, 7 figures - Strongly revised version compared to first version.
Blicher, Andreas +1 more
openaire +7 more sources
Bubbles, Gating, and Anesthetics in Ion Channels [PDF]
Biophysical Journal, 2008 We suggest that bubbles are the bistable hydrophobic gates responsible for the on-off transitions of single channel currents. In this view, many types of channels gate by the same physical mechanism-dewetting by capillary evaporation-but different types of channels use different sensors to modulate hydrophobic properties of the channel wall and thereby
Roth, R. +3 more
openaire +3 more sources
PLoS Computational Biology, 2020 Understanding the gating mechanism of ion channel proteins is key to understanding the regulation of cell signaling through these channels. Channel opening and closing are regulated by diverse environmental factors that include temperature, electrical ...
Juhwan Lee +3 more
doaj +1 more source
Effects of ionic strength on gating and permeation of TREK-2 K2P channels.
PLoS ONE, 2021 In addition to the classical voltage-dependent behavior mediated by the voltage-sensing-domains (VSD) of ion channels, a growing number of voltage-dependent gating behaviors are being described in channels that lack canonical VSDs.
Linus J Conrad +2 more
doaj +1 more source
Fractional diffusion modeling of ion channel gating [PDF]
, 2004 An anomalous diffusion model for ion channel gating is put forward. This scheme is able to describe non-exponential, power-law like distributions of residence time intervals in several types of ion channels.
A. L. Hodgkin +15 more
core +1 more source
Capacitance fluctuations causing channel noise reduction in stochastic Hodgkin-Huxley systems [PDF]
, 2006 Voltage-dependent ion channels determine the electric properties of axonal cell membranes. They not only allow the passage of ions through the cell membrane but also contribute to an additional charging of the cell membrane resulting in the so-called ...
Adrian R H +22 more
core +3 more sources
Membrane mechanics as a probe of ion-channel gating mechanisms [PDF]
, 2008 The details of conformational changes undergone by transmembrane ion channels in response to stimuli, such as electric fields and membrane tension, remain controversial.
Kondev, Jane +4 more
core +1 more source
eLife, 2021 Ligand-gated ion channels conduct currents in response to chemical stimuli, mediating electrochemical signaling in neurons and other excitable cells.
Cathrine Bergh +3 more
doaj +1 more source
Hydrophobic Gating in Ion Channels
Journal of Molecular Biology, 2015 Biological ion channels are nanoscale transmembrane pores. When water and ions are enclosed within the narrow confines of a sub-nanometer hydrophobic pore, they exhibit behavior not evident from macroscopic descriptions. At this nanoscopic level, the unfavorable interaction between the lining of a hydrophobic pore and water may lead to stochastic ...
Aryal, P, Sansom, MS, Tucker, S
openaire +3 more sources
Transcending Markov: non-Markovian rate processes of thermosensitive TRP ion channels
Royal Society Open Science, 2023 The Markov state model (MSM) is a popular theoretical tool for describing the hierarchy of time scales involved in the function of many proteins especially ion channel gating. An MSM is a particular case of the general non-Markovian model, where the rate
Yuval Ben-Abu +2 more
doaj +1 more source