Results 31 to 40 of about 5,284,490 (388)
International Journal of Molecular Sciences, 2020 The special issue “Ion Channels of Nociception” contains 13 articles published by 73 authors from different countries united by the main focusing on the peripheral mechanisms of pain.
Rashid Giniatullin
semanticscholar +1 more source
Human Molecular Genetics, 2002 Ion channels serve many functions apart from electrical signal transduction: chemical signalling (Ca(2+) as a second messenger), transepithelial transport, regulation of cytoplasmic or vesicular ion concentration and pH, and regulation of cell volume. Therefore, ion channel dysfunction can cause diseases in many tissues.
Christian A, Hübner, Thomas J, Jentsch
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Frontiers in Physiology, 2021 Background: Endurance athletes are prone to bradyarrhythmias, which in the long-term may underscore the increased incidence of pacemaker implantation reported in this population.
Isabelle Bidaud +19 more
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Mechanosensitive Ion Channels: Structural Features Relevant to Mechanotransduction Mechanisms.
Annual Review of Neuroscience, 2020 Activation of mechanosensitive ion channels underlies a variety of fundamental physiological processes that require sensation of mechanical force. Different mechanosensitive channels adapt distinctive structures and mechanotransduction mechanisms to fit ...
P. Jin, L. Jan, Y. Jan
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Ion channels and ion selectivity. [PDF]
Essays in Biochemistry, 2017 Specific macromolecular transport systems, ion channels and pumps, provide the pathways to facilitate and control the passage of ions across the lipid membrane. Ion channels provide energetically favourable passage for ions to diffuse rapidly and passively according to their electrochemical potential.
B. Roux
semanticscholar +3 more sources
Exploring the Two Coupled Conformational Changes That Activate the Munc18-1/Syntaxin-1 Complex
Frontiers in Molecular Neuroscience, 2021 Calcium-dependent synaptic vesicle exocytosis is mediated by SNARE complex formation. The transition from the Munc18-1/syntaxin-1 complex to the SNARE complex is catalyzed by the Munc13-1 MUN domain and involves at least two conformational changes ...
Jihong Gong +6 more
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Ion Channel Pharmacology [PDF]
Neurotherapeutics, 2007 Because ion channels are involved in many cellular processes, drugs acting on ion channels have long been used for the treatment of many diseases, especially those affecting electrically excitable tissues. The present review discusses the pharmacology of voltage-gated and neurotransmitter-gated ion channels involved in neurologic diseases, with ...
CONTE, Diana +2 more
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Neurobiology of Disease, 2023 SCN1A gain-of-function variants are associated with early onset developmental and epileptic encephalopathies (DEEs) that possess distinct clinical features compared to Dravet syndrome caused by SCN1A loss-of-function.
Géza Berecki +3 more
doaj +1 more source
Effect of channel block on the spiking activity of excitable membranes in a stochastic Hodgkin-Huxley model [PDF]
, 2004 The influence of intrinsic channel noise on the spontaneous spiking activity of poisoned excitable membrane patches is studied by use of a stochastic generalization of the Hodgkin-Huxley model.
Chow C C +17 more
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Self-assembled Artificial Ion-Channels toward Natural Selection of Functions.
Angewandte Chemie, 2020 Owing to their significant physiological functions, especially as selective relays for translocation of physiological relevant species through cellular membranes, natural ion channels play important role in the living organisms.
Shaoping Zheng +3 more
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