Results 31 to 40 of about 904,732 (368)
P2X receptors: epithelial ion channels and regulators of salt and water transport. [PDF]
, 2008 When the results from electrophysiological studies of renal epithelial cells are combined with data from in vivo tubule microperfusion experiments and immunohistochemical surveys of the nephron, the accumulated evidence suggests that ATP-gated ion ...
Brian F. King +29 more
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Ion Channels of Nociception [PDF]
International Journal of Molecular Sciences, 2020 The special issue “Ion Channels of Nociception” contains 13 articles published by 73 authors from different countries united by the main focusing on the peripheral mechanisms of pain. The content covers the mechanisms of neuropathic, inflammatory, and dental pain as well as pain in migraine and diabetes, nociceptive roles of P2X3, ASIC, Piezo and TRP ...
openaire +3 more sources
A TR(i)P to Cell Migration: New Roles of TRP Channels in Mechanotransduction and Cancer
Frontiers in Physiology, 2019 Cell migration is a key process in cancer metastasis, allowing malignant cells to spread from the primary tumor to distant organs. At the molecular level, migration is the result of several coordinated events involving mechanical forces and cellular ...
Jimena Canales +14 more
doaj +1 more source
Role of the TRPV Channels in the Endoplasmic Reticulum Calcium Homeostasis
Cells, 2020 It has been widely established that transient receptor potential vanilloid (TRPV) channels play a crucial role in calcium homeostasis in mammalian cells.
Aurélien Haustrate +2 more
doaj +1 more source
Nature Communications, 2022 Photoactivable toxins targeting ion channels have great potential to control cell activity. Here the authors report HwTxIV-Nvoc, a UV light-cleavable and photoactivatable peptide that targets voltage-gated sodium channels; they validate this in cells ...
Jérôme Montnach +15 more
doaj +1 more source
Multidimensional Regulation of Cardiac Mitochondrial Potassium Channels
Cells, 2021 Mitochondria play a fundamental role in the energetics of cardiac cells. Moreover, mitochondria are involved in cardiac ischemia/reperfusion injury by opening the mitochondrial permeability transition pore which is the major cause of cell death.
Bogusz Kulawiak +2 more
doaj +1 more source
Structure and permeability of ion-channels by integrated AFM and waveguide TIRF microscopy. [PDF]
, 2014 Membrane ion channels regulate key cellular functions and their activity is dependent on their 3D structure. Atomic force microscopy (AFM) images 3D structure of membrane channels placed on a solid substrate.
Arce, Fernando Teran +5 more
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Suppression of nano-channel ion conductance by electro-osmotic flow in nano-channels with weakly overlapping electrical double layers [PDF]
, 2016 This theoretical study investigates the nonlinear ionic current-voltage characteristics of nano-channels that have weakly overlapping electrical double layers.
Dutton, Robert +4 more
core +3 more sources
, 1990 A relativistic electron beam propagating through a plasma in the ion-focused regime exhibits an electromagnetic instability at a resonant frequency {omega} {approximately} 2{gamma}{sup 2} {omega}{sub {beta}}. Growth is enhanced by optical guiding in the ion channel, which acts as dielectric waveguide, with fiber parameter V {approximately} 2 (I/I{sub A}
Whittum, D H, Sessler, A M, Dawson, J M
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TRPM8 Puts the Chill on Prostate Cancer
Pharmaceuticals, 2016 Prostate cancer (PCa) is one of the most frequently diagnosed cancers in developed countries. Several studies suggest that variations in calcium homeostasis are involved in carcinogenesis. Interestingly, (Transient Receptor Potential Melastatin member 8)
Guillaume P. Grolez, Dimitra Gkika
doaj +1 more source