Results 71 to 80 of about 810,377 (300)
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Excitatory synchronization of rat hippocampal interneurons during network activation in vitro
IntroductionHippocampal interneurons (INs) are known to synchronize their electrical activity via mechanisms, which are poorly defined due to immense complexity of neural tissue but seem to depend on local cell interactions and intensity of network ...
Viktoria S. Pendeliuk, Igor V. Melnick
doaj +1 more source
Technologies for trapped-ion quantum information systems [PDF]
Scaling-up from prototype systems to dense arrays of ions on chip, or vast networks of ions connected by photonic channels, will require developing entirely new technologies that combine miniaturized ion trapping systems with devices to capture, transmit
Bylinskii, Alexei +5 more
core +2 more sources
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Noise-assisted spike propagation in myelinated neurons
We consider noise-assisted spike propagation in myelinated axons within a multi-compartment stochastic Hodgkin-Huxley model. The noise originates from a finite number of ion channels in each node of Ranvier.
A. L. Hodgkin +11 more
core +1 more source
Triggering on hard probes in heavy ion collisions with CMS [PDF]
We present a study of the CMS trigger system in heavy-ion collisions. Concentrating on two physics channels, dimuons from decays of quarkonia and single jets, we evaluate a possible trigger strategy for Pb+Pb running that relies on event selection solely
Betts R +5 more
core +2 more sources
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Cardiovascular disease is the most prevalent age-related illness worldwide, causing approximately 15 million deaths every year. Hypertension is central in determining cardiovascular risk and is a strong predictive indicator of morbidity and mortality ...
Emma N. Bardsley +6 more
doaj +1 more source
Ion specificity and anomalous electrokinetic effects in hydrophobic nanochannels [PDF]
We demonstrate with computer simulations that anomalous electrokinetic effects, such as ion specificity and non-zero zeta potentials for uncharged surfaces, are generic features of electro-osmotic flow in hydrophobic channels. This behavior is due to the
Christophe Ybert +5 more
core +5 more sources
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source

