Results 11 to 20 of about 2,694 (167)
Nature Communications, 2021 Inositol hexakisphosphate (IP6) is a known assembly cofactor for HIV-1. Here, the authors show the role of IP6 in the assembly of the Rous sarcoma virus (RSV).
Martin Obr +2 more
exaly +2 more sources
How HIV-1 Uses the Metabolite Inositol Hexakisphosphate to Build Its Capsid [PDF]
VirusesThe HIV-1 capsid is one of virology’s most iconic structures, yet how it assembles has long remained elusive. Remarkably, the capsid is made from just a single protein, CA, which forms a lattice of ~250 hexamers and exactly 12 pentamers.
Leo C. James
doaj +2 more sources
FEBS Open Bio, 2014 Alzheimer’s disease (AD) is widely considered to be caused by amyloid-β peptide (Aβ) accumulation in the brain. Aβ is excised from amyloid-β precursor protein through sequential cleavage by β-secretase 1 (BACE1) and γ-secretase.
Masayuki Taniguchi
exaly +3 more sources
Phytic acid effect on periodontal ligament fibroblast: An in-vitro study.
PLoS ONE, 2023 ObjectivesThis study evaluated phytic acid (IP6) effect on the viability, alkaline phosphatase (ALP) activity and calcium release of human periodontal ligament (HPDL) cells in optimal (OGL) and elevated glucose level (EGL) in cell culture media.Materials
Smriti Aryal A C +5 more
doaj +1 more source
Phytic Acid: Properties and Potential Applications in Dentistry
Frontiers in Materials, 2021 Inositol hexaphosphate (IP6) is the most abundant inositol phosphate in nature and an essential molecule for different biological functions. IP6 has a unique structure granting it distinctive properties; a high negative charge density provides IP6 with ...
Mohannad Nassar +8 more
doaj +1 more source
Antimicrobial Activity of Phytic Acid: An Emerging Agent in Endodontics
Frontiers in Cellular and Infection Microbiology, 2021 BackgroundPhytic acid (IP6) is a promising and emerging agent, and because of its unique structure and distinctive properties, it lends itself to several applications in dentistry. Recently, IP6 was proposed as a potential chelating agent in endodontics.
Rania Nassar +8 more
doaj +1 more source
Application of Inositol Hexaphosphate and Inositol in Dental Medicine: An Overview
Biomolecules, 2023 Phosphorylated inositol hexaphosphate (IP6) is a naturally occurring carbohydrate, and its parent compound, myoinositol (Ins), is abundantly present in plants, particularly in certain high-fiber diets, but also in mammalian cells, where they regulate ...
Ana Druzijanic +5 more
doaj +1 more source
Resin-Based Cement Applied to Enamel and Dentin Pre-Treated with Phytic Acid: An In Vitro Study
Applied Sciences, 2021 Phytic acid (IP6) has the ability to etch tooth structure due to its acidity and chelating properties. This study aimed to evaluate the micro-tensile bond strength (μTBS) of resin-based cement to enamel and dentin using manufacturer-provided etchants ...
Mohannad Nassar +5 more
doaj +1 more source
Structural insight into host plasma membrane association and assembly of HIV-1 matrix protein
Scientific Reports, 2021 Oligomerization of Pr55Gag is a critical step of the late stage of the HIV life cycle. It has been known that the binding of IP6, an abundant endogenous cyclitol molecule at the MA domain, has been linked to the oligomerization of Pr55Gag.
Halilibrahim Ciftci +26 more
doaj +1 more source
Food & Nutrition Research, 2023 Background: Short bowel syndrome (SBS) has high morbidity and mortality rates, and promoting intestinal adaptation of the residual intestine is a critical treatment.
Weipeng Wang +8 more
doaj +1 more source