Results 91 to 100 of about 3,566 (193)

Light Therapy Alleviates Addiction‐Related Symptoms and Reshapes Habenula and Midbrain Pathways

open access: yesAdvanced Science, Volume 13, Issue 13, 3 March 2026.
This study investigates light therapy for treating Internet Gaming Disorder (IGD). Functional MRI (fMRI) data reveal that light therapy enhances brain connectivity, particularly between the habenula and the medial orbitofrontal cortex (mOFC). These changes are associated with reduced withdrawal symptoms and addiction severity, highlighting the ...
Jinhui Li   +10 more
wiley   +1 more source

Post‐Translational Modifications in Animal Circadian Clocks

open access: yesAdvanced Science, Volume 13, Issue 16, 18 March 2026.
Circadian clocks coordinate physiology with daily environmental cycles through conserved transcriptional–translational feedback loops. This review summarizes how post‐translational modifications fine‐tune clock function, highlights the evolutionary convergence of circadian timekeeping in Drosophila and mammals, and emphasizes the central of these ...
Xianhui Liu, Yong Zhang
wiley   +1 more source

Parallel Inhibition of Dopamine Amacrine Cells and Intrinsically Photosensitive Retinal Ganglion Cells in a Non-Image-Forming Visual Circuit of the Mouse Retina [PDF]

open access: yes, 2015
An inner retinal microcircuit composed of dopamine (DA)-containing amacrine cells and melanopsin-containing, intrinsically photosensitive retinal ganglion cells (M1 ipRGCs) process information about the duration and intensity of light exposures ...
Vuong, Helen E   +3 more
core   +1 more source

Linking Photophobia, Sleep Disturbances, and Migraine Chronicity: Evidence From a Retrospective Analysis

open access: yesBrain and Behavior, Volume 16, Issue 3, March 2026.
This study demonstrated that ictal photophobia was present in 89.8% and interictal photophobia in 93.4% of patients. Sleep disturbances were common, with 44.9% reporting difficulty falling asleep. Network analysis revealed stronger associations between interictal photophobia, daytime sleepiness, and medication overuse in chronic migraine compared to ...
Seden Demirci   +7 more
wiley   +1 more source

Total number and morphology of ipRGCs in control and STZ-diabetic mice at 12 weeks post-onset of diabetes.

open access: yes, 2014
(A) Representative flat-mounted retinas from a control and a STZ-diabetic animal, immunostained with melanopsin antibody. (B) Total number of ipRGCs. No difference was observed between groups.
Mohamed Bennis (480085)   +4 more
core   +1 more source

Digital Sleep Disruption: Unraveling the Network Structure of Technology Use and Sleep Problems Through Network Analysis

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 2, February 2026.
In 9443 Chinese adults, network analysis reveals blue light exposure as the central factor most strongly associated with sleep problems (r = 0.31). General screen time shows minimal direct effects (r = 0.03), with sleep disruption mediated through evening‐specific behaviors.
Haoqing Gan, Lingjia Xu, Chenglin Tong
wiley   +1 more source

Light-evoked Ca2+ responses in ipRGCs in the absence and presence of carbenoxolone.

open access: yes, 2013
(a) The light-evoked elevation in [Ca2+]i in an isolated ipRGC was completely blocked in the presence of 100 µM carbenoxolone (CBX) with only partial recovery after the third light pulse presented after 45 min of wash out.
Gary E. Pickard (312753)   +3 more
core   +1 more source

Light-induced c-Fos expression in ipRGCs lacking melanopsin.

open access: yes, 2013
The percentage of β-galactosidase-positive ipRGCs expressing Fos in the retinas of tau-lacZ+/+ mice three hr after light onset or at the same time of day but in the dark is shown on the far left of the histogram (white light = 1000 lux; n = 3 animals ...
Malcolm D. Ogilvie (373840)   +3 more
core   +1 more source

Regulation of Reentrainment Function Is Dependent on a Certain Minimal Number of Intact Functional ipRGCs in rd Mice

open access: yesJournal of Ophthalmology, 2017
Purpose. To investigate the effect of partial ablation of melanopsin-containing retinal ganglion cells (mcRGCs) on nonimage-forming (NIF) visual functions in rd mice lacking rods. Methods.
Jingxue Zhang   +4 more
doaj   +1 more source

Does the spectral sensitivity of melanopsin in ipRGCs suggest a role in chromatic adaptation?

open access: yesJournal of Vision, 2018
Poster presented at VSS 2018, Floridadoi.org/10.1167/18.10.877https://jov.arvojournals.org/article.aspx?articleid=2699866Abstract: Here we examine whether the spectral sensitivity of melanopsin, the light sensitive protein in the intrinsically photosensitive retinal ganglion cells (ipRGCs), could play a role in chromatic adaptation by providing a ...
Garside, Daniel   +2 more
openaire   +1 more source

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