Results 111 to 120 of about 1,216 (154)

Syngeneic Mouse Models of Oral Cancer Are Effectively Targeted by Anti–CD44-Based NIR-PIT

, 2017
Oral cavity squamous cell carcinoma (OSCC) is considered one of the most aggressive subtypes of cancer. Anti-CD44 monoclonal antibodies (mAb) are a potential therapy against CD44 expressing OSCC; however, to date the therapeutic effects have been ...
Tadanobu Nagaya, Fusa Ogata, Yuko Nakamura, Shuhei Okuyama, Yasuhiro Maruoka, Hisataka Kobayashi, Clint Allen, Peter L. Choyke   +7 more
core   +1 more source

Supplementary Figures S1-S8 from Theranostic Agents for Photodynamic Therapy of Prostate Cancer by Targeting Prostate-Specific Membrane Antigen

, 2016
Figure S1: Related PSMA ligands Figure S2: Schematic illustration for the synthesis of PSMA-1-SMCC and characterization of PSMA-1-SMCC Figure S3: Schematic illustration for the synthesis of PSMA-1-Pc413 and characterization of PSMA-1-Pc413 Figure S4 ...
James P. Basilion (94283), Ping Zhang (86495), Gopolakrishnan Ramamurthy (14941858), Xinning Wang (2591230), Malcolm E. Kenney (2049469), Jonathan Kiechle (15074454), Lee Ponsky (5706497), Brian Tsui (3874495), Joseph Meyers (1967392)   +8 more
core   +1 more source

Molecularly Targeted Cancer Combination Therapy with Near-Infrared Photoimmunotherapy and Near-Infrared Photorelease with Duocarmycin–Antibody Conjugate

, 2018
Near-infrared photoimmunotherapy (NIR-PIT) is a highly selective tumor treatment that uses an antibody–photoabsorber conjugate (APC). However, the effect of NIR-PIT can be enhanced when combined with other therapies.
Tadanobu Nagaya, Fusa Ogata, Roger R. Nani, Shuhei Okuyama, Yasuhiro Maruoka, Hisataka Kobayashi, Martin J. Schnermann, Alexander P. Gorka, Peter L. Choyke   +8 more
core   +1 more source

Cetuximab-IR700 Conjugate RM-1929 [PDF]

, 2020
openaire   +1 more source

Photoinduced Ligand Release from a Silicon Phthalocyanine Dye Conjugated with Monoclonal Antibodies: A Mechanism of Cancer Cell Cytotoxicity after Near-Infrared Photoimmunotherapy

, 2018
Photochemical reactions can dramatically alter physical characteristics of reacted molecules. In this study, we demonstrate that near-infrared (NIR) light induces an axial ligand-releasing reaction, which dramatically alters hydrophilicity of a silicon ...
Shuhei Okuyama (3955442), Tadanobu Nagaya (789144), Masayuki Nishimura (2513881), Kanta Ando (3073791), Hideo Takakura (1628860), Shiho Moriguchi (5929226), Shinichiro Totoki (5929232), Tairo Ogura (5929229), Peter L. Choyke (542638), Yoshinori Hasegawa (308240), Mikako Ogawa (540357), Hirofumi Hanaoka (484936), Hisataka Kobayashi (1859), Kazuhide Sato (662171), Ryohei Kokawa (2081689)   +14 more
core   +1 more source

Near-infrared photoimmunotherapy using antiGD2 antibody for neuroblastoma and osteosarcoma

EJC Paediatric Oncology
Introduction: Near-infrared photoimmunotherapy (NIR-PIT) is a novel cancer therapy that specifically targets cancer cells. In NIR-PIT, antibody-photo-absorber-conjugates (APCs), specific for cancer antigens, target cancer cells.
Jimei Zhao, Kohei Nakajima, Masahiro Ueki, Yukayo Terashita, Shinsuke Hirabayashi, Yuko Cho, Mikako Ogawa, Atsushi Manabe   +7 more
doaj   +1 more source

Supplementary Figure S3: The characteristics of SKOV-3/Luc cells from Trastuzumab-Based Photoimmunotherapy Integrated with Viral HER2 Transduction Inhibits Peritoneally Disseminated HER2-Negative Cancer

, 2016
The characteristics of SKOV-3/Luc cells. The human ovarian cancer cell line SKOV-3/Luc is known to be HER2-positive. A, Western blot analysis showed the expression of wt-HER2 protein (185 kDa) in SKOV-3/Luc cells, the same as in N87 cells.
Michihiro Ishida (15069690), Kyoko Shimoyama (15069693), Yasuhiro Shirakawa (14904657), Hisataka Kobayashi (1859), Kazuhiro Noma (14799550), Hiroshi Tazawa (157738), Shunsuke Tanabe (7540496), Toshiyoshi Fujiwara (157767), Shunsuke Kagawa (157766), Kiyoto Takehara (2157013)   +9 more
core   +1 more source

Internalization-Dependent EGFR-Targeted Photoactivation by Cetuximab-I21 Conjugates. [PDF]

J Immunother
Shang W, Shang H, Cai J, Vicky Q, Chen L, Wang H, Zhang X.   +6 more
europepmc   +1 more source

Mirabody–IR700: A novel EGFR-targeting platform for photoimmunotherapy

Biomedicine & Pharmacotherapy
Citra R.A.P. Palangka, Motofumi Suzuki, Ayaka Kanai, Azusa Nitta, Junichi Takagi, Hirofumi Hanaoka   +5 more
openaire   +1 more source

Near infrared photo-bacterialflora modulation technology realized controlling periodontitis: modulation of disease-associated dysbiosis in oral microbiota using near infrared photo-antibacterial targeting therapy (NIR-PAT²). [PDF]

J Transl Med
Maruyama H, Sato K, Sakai K, Yasui H, Okada R, Xinheng L, Umeda K, Rahman S, Nguyen VS, Hibi H.   +9 more
europepmc   +1 more source