Results 161 to 170 of about 15,549 (206)

Pyrazolylpyrimidinamines Decorated via Petasis Reaction as Small-Molecule Activators of the RNA-Degrading Ribonuclease IRE1α. [PDF]

open access: yesACS Bio Med Chem Au
Avathan Veettil AK   +7 more
europepmc   +1 more source

Regulation of Endoplasmic Reticulum Stress by Empagliflozin in Doxorubicin-Induced Cardiotoxicity in Rats. [PDF]

open access: yesJ Cell Mol Med
Malik A   +6 more
europepmc   +1 more source

Integrated molecular and metabolomic assessment of copper hydroxide nanopesticide toxicity in zebrafish. [PDF]

open access: yesFish Physiol Biochem
Aksakal FI   +5 more
europepmc   +1 more source

Pharmacological Targeting of IRE1 in Cancer [PDF]

open access: yesTrends in Cancer, 2020
IRE1α (inositol requiring enzyme 1 alpha) is one of the main transducers of the unfolded protein response (UPR). IRE1α plays instrumental protumoral roles in several cancers, and high IRE1α activity has been associated with poorer prognoses. In this context, IRE1α has been identified as a potentially relevant therapeutic target.
Dimitrios Doultsinos   +2 more
exaly   +5 more sources

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