Results 51 to 60 of about 83,013 (204)

Structures and functions of mitochondrial ABC transporters [PDF]

, 2015
A small number of physiologically important ATP-binding cassette (ABC) transporters are found in mitochondria. Most are half transporters of the B group forming homodimers and their topology suggests they function as exporters.
Aller, Ardehali, Balk, Bayeva, Belinda Faust, Bernard, Chen, Chen, Chen, Chitra A. Shintre, Chloupková, Christensen, Csere, Dawson, Dudek, Elisabeth P. Carpenter, Feissner, Giegé, Gompf, Graf, Gutmann, Hendrik W. van Veen, Higgins, Higgins, Hofacker, Hogue, Hyde, Ichikawa, Janneke Balk, Jin, Kessler, Kispal, Kispal, Kiss, Kiss, Krishnamurthy, Krüssel, Kuhnke, Kushnir, Lee, Leighton, Li, Liesa, Lill, Lill, Mikolay, Mitsuhashi, Paterson, Pondarré, Pondarré, Poor, Qi, Rayapuram, San Francisco, Schaedler, Senbongi, Shintre, Shirihai, Srinivasan, Teschner, Theresia A. Schaedler, Tiranti, Tsuchida, Vasundara Srinivasan, Ward, Yamamoto, Young, Zhang   +67 more
core   +2 more sources

Role of GSH and Iron-Sulfur Glutaredoxins in Iron Metabolism—Review

Molecules, 2020
Glutathione (GSH) was initially identified and characterized for its redox properties and later for its contributions to detoxification reactions. Over the past decade, however, the essential contributions of glutathione to cellular iron metabolism have ...
Trnka Daniel, Hossain Md Faruq, Jordt Laura Magdalena, Gellert Manuela, Lillig Christopher Horst   +4 more
doaj   +1 more source

Mammalian frataxin directly enhances sulfur transfer of NFS1 persulfide to both ISCU and free thiols [PDF]

, 2014
Friedreich's ataxia is a severe neurodegenerative disease caused by the decreased expression of frataxin, a mitochondrial protein that stimulates iron sulfur (Fe-S) cluster biogenesis.
Belot, Laura, Cornu, David, D'Autréaux, Benoit, Elduque Busquets, Xavier, Grandas Sagarra, Anna, Le Caer, Jean-Pierre, Parent, Aubérie, Toledano, Michel B.   +7 more
core   +2 more sources

Identification of Sequences Encoding Symbiodinium minutum Mitochondrial Proteins. [PDF]

, 2016
The dinoflagellates are an extremely diverse group of algae closely related to the Apicomplexa and the ciliates. Much work has previously been undertaken to determine the presence of various biochemical pathways within dinoflagellate mitochondria ...
Butterfield, Erin R., Howe, Christopher J., Nisbet, R. Ellen R.   +2 more
core   +4 more sources

NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis [PDF]

, 2017
Environmental nutrient levels impact cancer cell metabolism, resulting in context-dependent gene essentiality. Here, using loss-of-function screening based on RNA interference, we show that environmental oxygen levels are a major driver of differential ...
Adams, Sylvia, Alvarez, Samantha W., Birsoy, Kıvanç, Moreira, Andre L., Papagiannakopoulos, Thales, Possemato, Richard, Sabatini, David, Sviderskiy, Vladislav O., Terzi, Erdem M.   +8 more
core   +1 more source

Clinical, biochemical, and genetic spectrum of seven patients with NFU1 deficiency [PDF]

, 2015
Disorders of the mitochondrial energy metabolism are clinically and genetically heterogeneous. An increasingly recognized subgroup is caused by defective mitochondrial iron-sulfur (Fe-S) cluster biosynthesis, with defects in 13 genes being linked to ...
Angela eHagendorff, Arnaud V Vanlander, Barbara ePlecko, Boris eRolinski, Charlotte L Alston, Christine eMakowski, Franz A Zimmermann, Holger eProkisch, Holger eProkisch, Johannes A Mayr, Joél eSmet, Lucia eAbela, Maja eHempel, Marianne eRohrbach, Peter eFreisinger, Robert W Taylor, Rudy eVan Coster, Saikat eSantra, Sara eSeneka, Stephanie eSpranger, Steven A Hardy, Thomas eMeitinger, Thomas eMeitinger, Tobias Bernd Haack, Tobias Bernd Haack, Uwe eAhting, Wolfgang eSperl   +26 more
core   +3 more sources

Interaction of the Streptomyces Wbl protein WhiD with the principal sigma factor σHrdB depends on the WhiD [4Fe-4S] cluster [PDF]

, 2020
The bacterial protein WhiD belongs to the Wbl family of iron–sulfur [Fe-S] proteins present only in the actinomycetes. In Streptomyces coelicolor, it is required for the late stages of sporulation, but precisely how it functions is unknown.
Bush, Matthew, Buttner, Mark, Crack, Jason, Le Brun, Nick, Stewart, Melissa   +4 more
core   +1 more source

Intermediate Element Abundances in Galaxy Clusters

, 2003
We present the average abundances of the intermediate elements obtained by performing a stacked analysis of all the galaxy clusters in the archive of the X-ray telescope ASCA.
Arnaud M., Cappellaro E., D. J. Horner, Fukazawa Y., Gibson B. K., Grevesse N., Grevesse N., Guainazzi M., Ishimaru Y., M. Loewenstein, Matsumoto H., Mitchell R. J., Peimbert M., R. F. Mushotzky, Tanaka Y., W. H. Baumgartner   +15 more
core   +1 more source

Rustless translation [PDF]

, 2012
ATP binding cassette proteins are a large and diverse family of molecular machines and include transmembrane transporter, chromosome maintenance and DNA repair proteins, and translation factors.
Karl-Peter Hopfner, Roy
core   +1 more source

Methanosarcina acetivorans contains a functional ISC system for iron-sulfur cluster biogenesis

BMC Microbiology, 2020
Background The production of methane by methanogens is dependent on numerous iron-sulfur (Fe-S) cluster proteins; yet, the machinery involved in Fe-S cluster biogenesis in methanogens remains largely unknown.
Thomas M. Deere, Divya Prakash, Faith H. Lessner, Evert C. Duin, Daniel J. Lessner   +4 more
doaj   +1 more source