Results 11 to 20 of about 31,278 (263)

Sulfur Administration in Fe–S Cluster Homeostasis

open access: yesAntioxidants, 2021
Mitochondria are the key organelles of Fe–S cluster synthesis. They contain the enzyme cysteine desulfurase, a scaffold protein, iron and electron donors, and specific chaperons all required for the formation of Fe–S clusters.
Leszek Rydz   +2 more
doaj   +1 more source

Biophysical Characterization of Iron-Sulfur Proteins

open access: yesBio-Protocol, 2021
Iron-sulfur proteins are primordial catalysts and biological electron carriers that today drive major metabolic pathways across all forms of life. They can access a diversity of oxidation states and can mediate electron transfer over an extended range of
Bhanu Jagilinki   +4 more
doaj   +1 more source

Iron–Sulfur Cluster Biogenesis and Iron Homeostasis in Cyanobacteria

open access: yesFrontiers in Microbiology, 2020
Iron–sulfur (Fe–S) clusters are ancient and ubiquitous cofactors and are involved in many important biological processes. Unlike the non-photosynthetic bacteria, cyanobacteria have developed the sulfur utilization factor (SUF) mechanism as their main ...
Fudan Gao
doaj   +1 more source

Recent Advances in the Elucidation of Frataxin Biochemical Function Open Novel Perspectives for the Treatment of Friedreich’s Ataxia

open access: yesFrontiers in Neuroscience, 2022
Friedreich’s ataxia (FRDA) is the most prevalent autosomic recessive ataxia and is associated with a severe cardiac hypertrophy and less frequently diabetes.
Beata Monfort   +3 more
doaj   +1 more source

Structure-function relationships of the Mycobacterium tuberculosis transcription factor WhiB1.

open access: yesPLoS ONE, 2012
BackgroundMembers of the WhiB-like (Wbl) protein family possess iron-sulfur clusters and are implicated in the regulation of developmental processes in Actinomycetes. Mycobacterium tuberculosis possesses seven Wbl proteins.
Laura J Smith   +3 more
doaj   +1 more source

Description of peptide bond planarity from high-resolution neutron crystallography

open access: yesBiophysics and Physicobiology, 2023
Neutron crystallography is a highly effective method for visualizing hydrogen atoms in proteins. In our recent study, we successfully determined the high-resolution (1.2 Å) neutron structure of high-potential iron-sulfur protein, refining the coordinates
Yuya Hanazono   +3 more
doaj   +1 more source

Down the Iron Path: Mitochondrial Iron Homeostasis and Beyond

open access: yesCells, 2021
Cellular iron homeostasis and mitochondrial iron homeostasis are interdependent. Mitochondria must import iron to form iron–sulfur clusters and heme, and to incorporate these cofactors along with iron ions into mitochondrial proteins that support ...
Jonathan V. Dietz   +2 more
doaj   +1 more source

Cluster and fold stability of E. coli ISC-type ferredoxin.

open access: yesPLoS ONE, 2013
Iron-sulfur clusters are essential protein prosthetic groups that provide their redox potential to several different metabolic pathways. Formation of iron-sulfur clusters is assisted by a specialised machine that comprises, among other proteins, a ...
Robert Yan   +6 more
doaj   +1 more source

Mechanism of Iron–Sulfur Cluster Assembly: In the Intimacy of Iron and Sulfur Encounter

open access: yesInorganics, 2020
Iron–sulfur (Fe–S) clusters are protein cofactors of a multitude of enzymes performing essential biological functions. Specialized multi-protein machineries present in all types of organisms support their biosynthesis.
Batoul Srour   +3 more
doaj   +1 more source

Spectral decomposition of iron-sulfur clusters

open access: yesAnalytical Biochemistry, 2021
The near universal availability of UV-Visible spectrophotometers makes this instrument a highly exploited tool for the inexpensive, rapid examination of iron-sulfur clusters. Yet, the analysis of iron-sulfur cluster reconstitution experiments by UV-Vis spectroscopy is notoriously difficult due to the presence of broad, ill-defined peaks. Other types of
Isaiah O. Betinol   +2 more
openaire   +3 more sources

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