Influence of iron- and zinc-chelating agents on neutrophil extracellular trap formation
Release of neutrophil extracellular traps (NETs) is one of the neutrophils’ mechanisms involved in the response to infection. NETs are released from the cell in response to a biological or synthetic stimulus to entrap, immobilize and kill pathogens ...
Weronika Kuźmicka +5 more
doaj +1 more source
Evaluation of ATC as an Orally Administered Drug in Treatment of Cadmium Toxicity of Rat Organs
The effect of N-tetramethylene dithiocarbamate (ATC) as a chelating agent on the excretion of cadmium was evaluated in cadmium-poisoned Wistar rats following administration through food and drink.
S. Nabilaldine Fatemi +3 more
doaj +1 more source
Injectable Thermosensitive Hydrogels for a Sustained Release of Iron Nanochelators
Deferoxamine (DFO) is an FDA‐approved iron‐chelating agent which shows good therapeutic efficacy, however, its short blood half‐life presents challenges such as the need for repeated injections or continuous infusions.
Seung Hun Park +10 more
doaj +1 more source
Organometallic iridium(III) anticancer complexes with new mechanisms of action: NCI-60 screening, mitochondrial targeting, and apoptosis [PDF]
Platinum complexes related to cisplatin, cis-[PtCl2(NH3)2], are successful anticancer drugs; however, other transition metal complexes offer potential for combating cisplatin resistance, decreasing side effects, and widening the spectrum of activity ...
Bailey H. H. +67 more
core +1 more source
Selection of patients for iron-chelating therapy
Emergence of iron aggressive forms in patients with hematological or oncohematological diseases is potentially life-threatening. This can be caused by several situations: multiple allogeneic RBC transfusions, increased intestinal absorption of iron, or ...
S. V. Gritsaev +3 more
doaj +1 more source
Designing organometallic compounds for catalysis and therapy [PDF]
Bioorganometallic chemistry is a rapidly developing area of research. In recent years organometallic compounds have provided a rich platform for the design of effective catalysts, e.g. for olefin metathesis and transfer hydrogenation.
Abraha Habtemariam +188 more
core +1 more source
Iron Chelators as Potential Therapeutic Agents for Parkinsons Disease [PDF]
Parkinson's disease (PD) is a neurological disorder characterized by the progressive impairment of motor skills in patients. Growing evidence suggests that abnormal redox-active metal accumulation, caused by dysregulation, plays a central role in the neuropathology of PD. Redox-active metals (e.g.
Carlos A, Perez, Yong, Tong, Maolin, Guo
openaire +2 more sources
Zein‐Based Adhesives: Sustainable Extraction and Application in Bioadhesive Technologies
Zein is extracted from corn gluten meal using a simple and scalable process with high yield (~90%). The resulting protein is applied in bioadhesives modified with Ca2+ and Fe3+ ions, exhibiting substrate‐dependent adhesion. The findings demonstrate competitive bonding performance and highlight the role of ionic interactions in tuning adhesion ...
Paula Bertolino Sanvezzo +3 more
wiley +1 more source
Mangiferin: A Promising Anticancer Bioactive [PDF]
Of late, several biologically active antioxidants from natural products have been investigated by the researchers in order to combat the root cause of carcinogenesis, i.e., oxidative stress.
Acosta J +8 more
core +1 more source
Electroactive Metal–Organic Frameworks for Electrocatalysis
Electrocatalysis is crucial in sustainable energy conversion as it enables efficient chemical transformations. The review discusses how metal–organic frameworks can revolutionize this field by offering tailorable structures and active site tunability, enabling efficient and selective electrocatalytic processes.
Irena Senkovska +7 more
wiley +1 more source

