Results 61 to 70 of about 53,650 (299)

Trypanotoxic activity of thiosemicarbazone iron chelators. [PDF]

open access: yes, 2015
Only a few drugs are available for treating sleeping sickness and nagana disease; parasitic infections caused by protozoans of the genus Trypanosoma in sub-Saharan Africa.
Ellis, S, Sexton, DW, Steverding, D
core   +1 more source

Photothermal‐Activated Antibacterial Amyloid‐Polyphenol‐Iron Hydrogels for Synergistic Wound Healing

open access: yesAdvanced Healthcare Materials, EarlyView.
We report a thermally triggered supramolecular hydrogel (LTFe) formed by Fe3+ and tannic acid on lysozyme amyloid fibrils. Fe3+ enables rapid gelation and photothermal transduction with an efficiency of 88.56%. The LTFe hydrogel exhibits excellent biocompatibility, potent antibacterial activity against E. coli and S.
Di Wu   +8 more
wiley   +1 more source

SYNTHESIS OF N- ACETONITRIL AND N- ETHYLAMINE- 3- HYDROXYPYRIDINONES AS IRON (III) CHELATORS

open access: yesJournal of Research in Medical Sciences, 2000
<font><font color="#555555"><span style="font-size: 10pt; font-family: Tahoma">Background. The need of iron-chelating agents as orally active alternatives to desferal for the treatment of iron overload in thalassaemic patients, has ...
L.A. SAGHAEI
doaj  

Thiosemicarbazones and selected tyrosine kinase inhibitors synergize in pediatric solid tumors: NDRG1 upregulation and impaired prosurvival signaling in neuroblastoma cells

open access: yesFrontiers in Pharmacology, 2022
Tyrosine kinase inhibitors (TKIs) are frequently used in combined therapy to enhance treatment efficacy and overcome drug resistance. The present study analyzed the effects of three inhibitors, sunitinib, gefitinib, and lapatinib, combined with iron ...
Maria Krchniakova   +10 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

open access: yesAdvanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa   +3 more
wiley   +1 more source

Auto-combustion synthesis of perovskite-type oxides SrTi1−xFexO3−δ [PDF]

open access: yes, 2015
A versatile one-pot auto-combustion method for the synthesis of powders of iron-doped strontium titanate, SrTi1−xFexO3−δ, has been developed. The synthesis is optimized by the combined use of EDTA and citric acid as chelating agents, and an appropriate ...
Bouwmeester, H.J.M.   +5 more
core   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

open access: yesAdvanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Production of pili, hemolysin and siderophores in the urinary isolates of Escherichia coli [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2013
Introduction. Escherichia coli (E. coli) are the most frequent cause of the urinary tract infections. Uropathogenic E. coli (UPEC) produce virulence factors which enable them to survive in the urinary tract and cause an infection. Objective.
Marković Tatjana   +2 more
doaj   +1 more source

Quantitative RNA-seq Analysis Unveils Osmotic and Thermal Adaptation Mechanisms Relevant for Ectoine Production in Chromohalobacter salexigens [PDF]

open access: yes, 2018
Quantitative RNA sequencing (RNA-seq) and the complementary phenotypic assays were implemented to investigate the transcriptional responses of Chromohalobacter salexigens to osmotic and heat stress.
Carmen Vargas   +6 more
core   +2 more sources

Effect of Atomic Layer Deposition of Ultra‐Thin Oxide on Reactivity and Durability of Perovskite Oxygen Electrodes

open access: yesAdvanced Materials, EarlyView.
This table of contents illustrates that the mechanism for mitigating Sr segregation depends strongly on the chemistry of the coating layer. HfO2 electrostatically stabilizes the surface by lowering the surface oxygen vacancies, which serve as the driving force for Sr migration. On the other hand, Al2O3 and Fe2O3 react with segregated Sr to form Sr‐Al‐O
Jongsu Seo   +8 more
wiley   +1 more source

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