Results 31 to 40 of about 53,650 (299)

New trends for metal complexes with anticancer activity [PDF]

open access: yes, 2008
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is,
Ang   +56 more
core   +1 more source

Brazilian Thalassemia Association protocol for iron chelation therapy in patients under regular transfusion

open access: yesRevista Brasileira de Hematologia e Hemoterapia, 2013
In the absence of an iron chelating agent, patients with beta-thalassemia on regular transfusions present complications of transfusion-related iron overload.
Monica Pinheiro de Almeida Verissimo   +10 more
doaj   +1 more source

Current applications and future potential for bioinorganic chemistry in the development of anticancer drugs [PDF]

open access: yes, 2009
This review illustrates notable recent progress in the field of medicinal bioinorganic chemistry as many new approaches to the design of innovative metal-based anticancer drugs are emerging.
Aird   +75 more
core   +1 more source

Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases

open access: yesMolecular Neurodegeneration, 2017
The homeostasis of iron is vital to human health, and iron dyshomeostasis can lead to various disorders. Iron homeostasis is maintained by iron regulatory proteins (IRP1 and IRP2) and the iron-responsive element (IRE) signaling pathway.
Zhi Dong Zhou, Eng-King Tan
doaj   +1 more source

Moroccan propolis: a natural antioxidant, antibacterial, and antibiofilm against Staphylococcus aureus with no induction of resistance after continuous exposure [PDF]

open access: yes, 2018
This study was performed to evaluate the total phenols, flavonoids, and antioxidant activities of twenty-four propolis samples from different regions of Morocco.
AAZZA, Smail   +7 more
core   +1 more source

Unlocking the in vitroanti- inflammatory and antidiabetic potential of Polygonum maritimum [PDF]

open access: yes, 2017
Context: Several Polygonum species (Polygonaceae) are used in traditional medicine in Asia, Europe and Africa to treat inflammation and diabetes. Objective: Evaluate the in vitro antioxidant, anti-inflammatory and antidiabetic potential of methanol and ...
Alice Martins   +16 more
core   +1 more source

Impact of Chelating Agent Salt Type on the Enhanced Oil Recovery from Carbonate and Sandstone Reservoirs

open access: yesApplied Sciences, 2021
In this paper, chelating agents were introduced as standalone fluids for enhancing the oil recovery from carbonate and sandstone reservoirs. Chelating agents such as glutamic acid di-acetic acid (GLDA), ethylene-diamine-tetra acetic acid (EDTA), and ...
Amjed Hassan   +2 more
doaj   +1 more source

Characterizing RecA-Independent Induction of Shiga toxin2-encoding Phages by EDTA Treatment [PDF]

open access: yes, 2013
The bacteriophage life cycle has an important role in Shiga toxin (Stx) expression. The induction of Shiga toxin-encoding phages (Stx phages) increases toxin production as a result of replication of the phage genome, and phage lysis of the host cell also
Imamovic, Lejla   +1 more
core   +2 more sources

Controlling platinum, ruthenium, and osmium reactivity for anticancer drug design [PDF]

open access: yes, 2009
The main task of the medicinal chemist is to design molecules that interact specifically with derailed or degenerating processes in a diseased organism, translating the available knowledge of pathobiochemical and physiological data into chemically ...
Bruijnincx, Pieter C. A., Sadler, P. J.
core   +1 more source

Spray Encapsulation of Iron in Chitosan Biopolymer for Tea Fortification

open access: yesJournal of Food Quality, 2023
Aim. Tea was studied as a carrier for iron in a fortification strategy to reduce iron deficiency. Iron forms insoluble coloured complexes with tea polyphenols which lower consumer acceptability.
Juveria Siddiqui   +5 more
doaj   +1 more source

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