Iron chelating agents for iron overload diseases [PDF]
Thalassemia Reports, 2014 Although iron is an essential element for life, an excessive amount may become extremely toxic both for its ability to generate reactive oxygen species, and for the lack in humans of regulatory mechanisms for iron excretion.
Guido Crisponi +2 more
doaj +2 more sources
Multipurpose Iron-Chelating Ligands Inspired by Bioavailable Molecules [PDF]
BiomoleculesBecause of their capacity to bind metals, metal chelators are primarily employed for therapeutic purposes, but they can also find applications as colorimetric reagents and cleaning solutions as well as in soil remediation, electroplating, waste treatment,
Elena Cini +7 more
doaj +2 more sources
Influence of chemical speciation on the separation of metal ions from chelating agents by nanofiltration membranes [PDF]
, 2020 The simultaneous separation of various metal ions (nickel, copper, calcium, and iron) from chelating agents (EDTA and citric acid) in water streams using Nanofiltration membranes is analyzed.
Labanda, Jordi +3 more
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Iron chelating agents for treating malaria.
, 2000 BACKGROUND: Mortality from Plasmodium falciparum malaria remains high; death and sequelae occur in even in patients treated with antimalarial drugs.
Meremikwu, M., Smith, H. J.
core +9 more sources
Formation Damage Due to Iron Precipitation during Matrix Acidizing Treatments of Carbonate Reservoirs and Ways to Minimize it Using Chelating Agents [PDF]
, 2013 Iron precipitation during matrix acidizing treatments is a well-known problem. During matrix acidizing, successful iron control can be critical to the success of the treatment.
Assem, Ahmed I
core +2 more sources
Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment
Biosensors, 2023 Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestations that vary ...
Zahra Tariq +4 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Metal chelating agents are antioxidant agents, which decrease the reductive potential and stabilize the oxidized metal ion form. In this study, we evaluated the naringin capacity in chelating iron and preventing amyloid-beta plaque formation in the ...
Mehrdad Jahanshahi +3 more
doaj +1 more source
A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. [PDF]
PLoS ONE, 2015 A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients.
Guido Crisponi +6 more
doaj +1 more source
Frontiers in Neurology, 2021 Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim +3 more
doaj +1 more source
Impact of Sappan Wood Extract as Iron Chelator Adjuvant on Iron Concentration and Macrophage Polarization in Rat Spleen [PDF]
Iranian Journal of Medical SciencesBackground: Iron accumulation in the spleen of thalassemia patients disrupts macrophage polarization, impairs immune function, and increases mortality.
Mohammad Ghozali +6 more
doaj +1 more source