Results 11 to 20 of about 21,184 (254)
Frontiers in Neurology, 2022 Studies have shown that iron accumulation in the brain leads to neurogenic disorders. Novel iron chelating agents such as natural remedies are useful to decrease the side effects of iron in the brain.
Mahdi AAlikhani +3 more
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Frontiers in Chemistry, 2021 Incorporating nanoparticles into devices for a wide range of applications often requires the formation of thick films, which is particularly necessary for improving magnetic power storage, microwave properties, and sensor performance.
Sara C. Mills +3 more
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Ferritin iron mobilisation by chelating agents [PDF]
FEBS Letters, 1980 In a large number of eukaryotes iron is stored in a soluble non-toxic form in ferritin. The iron is deposited in the interior of an approximately spherical protein shell, predominantly as ferric oxyhydroxide (reviewed [ 1,2] ). A number of mechanisms have been proposed for ferritin iron release involving low molecular weight chelators [3,4], enzyme ...
Crichton, Robert R. +2 more
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Incidence of Ocular Toxicity from Iron Chelating Agents at Siriraj Hospital
Siriraj Medical Journal, 2020 Objective: To determine the incidences of ocular toxicity and ocular findings, including structural and functional abnormalities, caused by iron chelating agents and detected by an electrophysiologic test at Siriraj Hospital.
Atiporn Thuangtong +2 more
doaj +1 more source
Pharmacogenetic Study of Deferasirox, an Iron Chelating Agent [PDF]
PLoS ONE, 2010 Abstract Abstract 2060 Transfusion associated iron overload induce systemic toxicity. Deferoxamine had been used to reduce iron induced toxicities by chelating iron but it is a short acting drug and needs parenteral administration.
Lee, Ji Won +12 more
openaire +5 more sources
A Case Study and a Brief Review on Dermatopathological Drug Reaction in Major Thalassemia [PDF]
Reviews in Clinical Medicine, 2023 Introduction: Thalassemia consists of a variety of genetic hemoglobinopathies. Thalassemia-major causes anemia in early age. Those suffering from thalassemia need frequent life-long blood transfusions to survive, resulting in iron overload in the body ...
Afshan Shirkavand +3 more
doaj +1 more source
Thalassemia and Nanotheragnostics: Advanced Approaches for Diagnosis and Treatment
Biosensors, 2023 Thalassemia is a monogenic autosomal recessive disorder caused by mutations, which lead to abnormal or reduced production of hemoglobin. Ineffective erythropoiesis, hemolysis, hepcidin suppression, and iron overload are common manifestations that vary ...
Zahra Tariq +4 more
doaj +1 more source
Frontiers in Pharmacology, 2021 Metal chelating agents are antioxidant agents, which decrease the reductive potential and stabilize the oxidized metal ion form. In this study, we evaluated the naringin capacity in chelating iron and preventing amyloid-beta plaque formation in the ...
Mehrdad Jahanshahi +3 more
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A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. [PDF]
PLoS ONE, 2015 A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients.
Guido Crisponi +6 more
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Frontiers in Neurology, 2021 Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim +3 more
doaj +1 more source