Results 21 to 30 of about 2,345,730 (271)

Naringin Chelates Excessive Iron and Prevents the Formation of Amyloid-Beta Plaques in the Hippocampus of Iron-Overloaded Mice

Frontiers in Pharmacology, 2021
Metal chelating agents are antioxidant agents, which decrease the reductive potential and stabilize the oxidized metal ion form. In this study, we evaluated the naringin capacity in chelating iron and preventing amyloid-beta plaque formation in the ...
Mehrdad Jahanshahi, Masoumeh Khalili, Masoumeh Khalili, Asra Margedari   +3 more
doaj   +1 more source

Iron Status Predicts Treatment Failure and Mortality in Tuberculosis Patients: A Prospective Cohort Study from Dar es Salaam, Tanzania. [PDF]

, 2012
Experimental data suggest a role for iron in the course of tuberculosis (TB) infection, but there is limited evidence on the potential effects of iron deficiency or iron overload on the progression of TB disease in humans. The aim of the present analysis
Spiegelman Donna, Sheila Isanaka, Walter C Willett, Mugusi Ferdinand, Isanaka Sheila, Isanaka, Sheila, Wafaie W Fawzi, Fawzi, Wafaie, Spiegelman, Donna, Christopher Duggan, Fawzi Wafaie W., Bosch, Ronald J, Said Aboud, Bosch Ronald J., Willett Walter C., Willett, Walter C, Aboud, Said, Ferdinand Mugusi, Mugusi, Ferdinand, Aboud Said, Ronald J Bosch, Duggan Christopher, Duggan, Christopher, Bosch, Ronald, Donna Spiegelman, Willett, Walter, Fawzi, Wafaie W   +26 more
core   +2 more sources

A Speciation Study on the Perturbing Effects of Iron Chelators on the Homeostasis of Essential Metal Ions. [PDF]

PLoS ONE, 2015
A number of reports have appeared in literature calling attention to the depletion of essential metal ions during chelation therapy on β-thalassaemia patients.
Guido Crisponi, Valeria Marina Nurchi, Miriam Crespo-Alonso, Gavino Sanna, Maria Antonietta Zoroddu, Giancarla Alberti, Raffaela Biesuz   +6 more
doaj   +1 more source

Formation Damage Due to Iron Precipitation during Matrix Acidizing Treatments of Carbonate Reservoirs and Ways to Minimize it Using Chelating Agents [PDF]

, 2013
Iron precipitation during matrix acidizing treatments is a well-known problem. During matrix acidizing, successful iron control can be critical to the success of the treatment.
Assem, Ahmed I
core   +3 more sources

Protective Effects of Deferoxamine on Vestibulotoxicity in Gentamicin-Induced Bilateral Vestibulopathy Rat Model

Frontiers in Neurology, 2021
Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim, Jin-Ok Lee, Ji-Soo Kim, Ji-Soo Kim   +3 more
doaj   +1 more source

Iron chelating agents for treating malaria.

, 2000
BACKGROUND: Mortality from Plasmodium falciparum malaria remains high; death and sequelae occur in even in patients treated with antimalarial drugs.
Meremikwu, M., Smith, H. J.
core   +9 more sources

Impact of Sappan Wood Extract as Iron Chelator Adjuvant on Iron Concentration and Macrophage Polarization in Rat Spleen [PDF]

Iranian Journal of Medical Sciences
Background: Iron accumulation in the spleen of thalassemia patients disrupts macrophage polarization, impairs immune function, and increases mortality.
Mohammad Ghozali, Ratu Safitri, Erick Khristian, Amethyst Puspita Ainni, Yasmi Purnamasari Kuntana, Muhamad Hasan Bashari, Jeri Nobia Purnama   +6 more
doaj   +1 more source

Iron Chelating Agents: Promising Supportive Therapies in Severe Cases of COVID-19? [PDF]

Trends in Pharmaceutical Sciences, 2020
Dear Editor, On December 2019, new cases of COVID-19 pneumonia were reported from Wuhan city of China that were consequences of 2019-nCoV or SARS-CoV-2 infection (1).
Parisa Ghasemiyeh, Soliman Mohammadi-Samani   +1 more
doaj   +1 more source

Detection of endocrine disorders in young children with multi-transfused thalassemia major

Italian Journal of Pediatrics, 2021
Background Beta thalassemia major (TM) is the most common inherited genetic disorder worldwide. Patients are at risk of iron overload, which leads to various forms of tissue damage, including endocrinopathies.
Ramadan A. Mahmoud, Ashraf Khodeary, Marwa S. Farhan   +2 more
doaj   +1 more source

Harnessing microbial iron chelators to develop innovative therapeutic agents

Journal of Advanced Research, 2022
Background: Bacterial infections involving multidrug-resistant Gram-negative bacteria have become critically involved in the current antibiotic crisis.
Marta Ribeiro, Cátia A. Sousa, Manuel Simões   +2 more
doaj   +1 more source