Results 21 to 30 of about 21,184 (254)

Iron Chelating Agents: Promising Supportive Therapies in Severe Cases of COVID-19? [PDF]

Trends in Pharmaceutical Sciences, 2020
Dear Editor, On December 2019, new cases of COVID-19 pneumonia were reported from Wuhan city of China that were consequences of 2019-nCoV or SARS-CoV-2 infection (1).
Parisa Ghasemiyeh, Soliman Mohammadi-Samani   +1 more
doaj   +1 more source

Impact of Sappan Wood Extract as Iron Chelator Adjuvant on Iron Concentration and Macrophage Polarization in Rat Spleen [PDF]

Iranian Journal of Medical Sciences
Background: Iron accumulation in the spleen of thalassemia patients disrupts macrophage polarization, impairs immune function, and increases mortality.
Mohammad Ghozali, Ratu Safitri, Erick Khristian, Amethyst Puspita Ainni, Yasmi Purnamasari Kuntana, Muhamad Hasan Bashari, Jeri Nobia Purnama   +6 more
doaj   +1 more source

Harnessing microbial iron chelators to develop innovative therapeutic agents

Journal of Advanced Research, 2022
Background: Bacterial infections involving multidrug-resistant Gram-negative bacteria have become critically involved in the current antibiotic crisis.
Marta Ribeiro, Cátia A. Sousa, Manuel Simões   +2 more
doaj   +1 more source

Detection of endocrine disorders in young children with multi-transfused thalassemia major

Italian Journal of Pediatrics, 2021
Background Beta thalassemia major (TM) is the most common inherited genetic disorder worldwide. Patients are at risk of iron overload, which leads to various forms of tissue damage, including endocrinopathies.
Ramadan A. Mahmoud, Ashraf Khodeary, Marwa S. Farhan   +2 more
doaj   +1 more source

EFFECT OF SOME CHELATING AGENTS ON BALANCE AND TISSUE DISTRIBUTION OF ESSENTIAL TRACE ELEMENTS IN TILAPIA FLORIDA [PDF]

Journal of Animal and Poultry Production, 2014
Three chelating agents, being  EDTA, thiamin and ascorbic acid were tested for balance and tissue distribution of  four essential trace elements, mainly, copper. zinc, iron and manganese, in Tilapia Florida.
doaj   +1 more source

Brazilian Thalassemia Association protocol for iron chelation therapy in patients under regular transfusion

Revista Brasileira de Hematologia e Hemoterapia, 2013
In the absence of an iron chelating agent, patients with beta-thalassemia on regular transfusions present complications of transfusion-related iron overload.
Monica Pinheiro de Almeida Verissimo, Sandra Regina Loggetto, Antonio Fabron Junior, Giorgio Roberto Baldanzi, Nelson Hamerschlak, Juliano Lara Fernandes, Aderson da Silva Araujo, Clarisse Lopes de Castro Lobo, Kleber Yotsumoto Fertrin, Vasilios Antonios Berdoukas, Renzo Galanello   +10 more
doaj   +1 more source

Iron regulatory protein (IRP)-iron responsive element (IRE) signaling pathway in human neurodegenerative diseases

Molecular Neurodegeneration, 2017
The homeostasis of iron is vital to human health, and iron dyshomeostasis can lead to various disorders. Iron homeostasis is maintained by iron regulatory proteins (IRP1 and IRP2) and the iron-responsive element (IRE) signaling pathway.
Zhi Dong Zhou, Eng-King Tan
doaj   +1 more source

Impact of Chelating Agent Salt Type on the Enhanced Oil Recovery from Carbonate and Sandstone Reservoirs

Applied Sciences, 2021
In this paper, chelating agents were introduced as standalone fluids for enhancing the oil recovery from carbonate and sandstone reservoirs. Chelating agents such as glutamic acid di-acetic acid (GLDA), ethylene-diamine-tetra acetic acid (EDTA), and ...
Amjed Hassan, Mohamed Mahmoud, Shirish Patil   +2 more
doaj   +1 more source

Evaluation of ATC as an Orally Administered Drug in Treatment of Cadmium Toxicity of Rat Organs

E-Journal of Chemistry, 2009
The effect of N-tetramethylene dithiocarbamate (ATC) as a chelating agent on the excretion of cadmium was evaluated in cadmium-poisoned Wistar rats following administration through food and drink.
S. Nabilaldine Fatemi, Solmaz Tubafard, S. Jamilaldine Fatemi, Behnam Nadi   +3 more
doaj   +1 more source

Spray Encapsulation of Iron in Chitosan Biopolymer for Tea Fortification

Journal of Food Quality, 2023
Aim. Tea was studied as a carrier for iron in a fortification strategy to reduce iron deficiency. Iron forms insoluble coloured complexes with tea polyphenols which lower consumer acceptability.
Juveria Siddiqui, Elisa June Teresa McGee, Deepak Mhasavade, Swathy Palagiri, V. Balamurugan, Levente László Diosady   +5 more
doaj   +1 more source