Introduction: Administration of aminoglycoside (AG) antibiotics is one of the most common causes of ototoxicity. This study aimed to determine the protective effects of deferoxamine, an iron-chelating agent, on vestibulotoxicity using an intratympanic ...
Hyo-Jung Kim +3 more
doaj +1 more source
Iron Chelating Agents: Promising Supportive Therapies in Severe Cases of COVID-19? [PDF]
Dear Editor, On December 2019, new cases of COVID-19 pneumonia were reported from Wuhan city of China that were consequences of 2019-nCoV or SARS-CoV-2 infection (1).
Parisa Ghasemiyeh +1 more
doaj +1 more source
Chelator free gallium-68 radiolabelling of silica coated iron oxide nanorods via surface interactions [PDF]
The commercial availability of combined magnetic resonance imaging (MRI)/positron emission tomography (PET) scanners for clinical use has increased demand for easily prepared agents which offer signal or contrast in both modalities.
Al-Yassiry, M.M. +23 more
core +2 more sources
Harnessing microbial iron chelators to develop innovative therapeutic agents
Background: Bacterial infections involving multidrug-resistant Gram-negative bacteria have become critically involved in the current antibiotic crisis.
Marta Ribeiro +2 more
doaj +1 more source
Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H. +6 more
core +3 more sources
Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]
Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa +14 more
core +4 more sources
Impact of Sappan Wood Extract as Iron Chelator Adjuvant on Iron Concentration and Macrophage Polarization in Rat Spleen [PDF]
Background: Iron accumulation in the spleen of thalassemia patients disrupts macrophage polarization, impairs immune function, and increases mortality.
Mohammad Ghozali +6 more
doaj +1 more source
Detection of endocrine disorders in young children with multi-transfused thalassemia major
Background Beta thalassemia major (TM) is the most common inherited genetic disorder worldwide. Patients are at risk of iron overload, which leads to various forms of tissue damage, including endocrinopathies.
Ramadan A. Mahmoud +2 more
doaj +1 more source
Inhibition of Xanthomonas fragariae, Causative Agent of Angular Leaf Spot of Strawberry, through Iron Deprivation. [PDF]
In commercial production settings, few options exist to prevent or treat angular leaf spot (ALS) of strawberry, a disease of economic importance and caused by the bacterial pathogen Xanthomonas fragariae.
Gebben, Samantha J +4 more
core +2 more sources
FeEDDHA-facilitated Fe uptake in relation to the behaviour of FeEDDHA components in the soil-plant system as a function of time and dosage. [PDF]
FeEDDHA products are widely used to prevent and remedy Fe chlorosis in crops grown on calcareous soils. These products consist of a mixture of FeEDDHA components: racemic o,o-FeEDDHA, meso o,o-FeEDDHA, o,p-FeEDDHA and rest-FeEDDHA. The FeEDDHA components
Schenkeveld, W.D.C. +3 more
core +2 more sources

