Results 21 to 30 of about 65,436 (336)
Haematologica, 2023 CALYPSO (clinicaltrials gov. Identifier: NCT02435212), a randomized, open-label, multicenter, phase II study evaluated the compliance, clinical benefits, and safety of deferasirox granules and dispersible tablets (DT) in pediatric patients with iron ...
Ali T. Taher +8 more
doaj +1 more source
Iron(III) chelating resins-IV. Crosslinked copolymer beads of 1-(B-acrylamidoethyl)-3-hydroxy-2-methyl-4(1H)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA) [PDF]
, 1994 Iron(III) chelating beads have been synthesized by copolymerization of 1-(ß-acrylamidoethyl)-3-hydroxy-2-methyl-4(IH)-pyridinone (AHMP) with 2-hydroxyethyl methacrylate (HEMA), and ethyleneglycol dimethacrylate (EGDMA) as the crosslinking agent.
Bantjes, A. +2 more
core +3 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2020 Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni +8 more
doaj +1 more source
Predictors of Non-adherence to iron chelation therapy in pediatric thalassemia patients
Journal of Rawalpindi Medical College, 2022 Objective: This study was conducted to identify predictors of non-adherence to iron chelation therapy among children suffering from β-thalassemia major across different treatment regimens.
Muniba Kanwal +3 more
doaj +1 more source
Haematologica, 2012 Background Plasma non-transferrin bound iron refers to heterogeneous plasma iron species, not bound to transferrin, which appear in conditions of iron overload and ineffective erythropoiesis.
Yesim Aydinok +3 more
doaj +1 more source
Interferon free antiviral treatment of chronic hepatitis C in patients affected by β-thalassemia major [PDF]
, 2017 Chronic hepatitis C (CHC) significantly affects the prognosis of liver disease [1] and health related quality of life (HRQOL) in patients with β-thalassemia major [2, 3].
Biliotti, Elisa +9 more
core +1 more source
A European survey on the detection and management of iron overload in transfusion-dependent patients with MDS [PDF]
, 2011 International audienceTo better understand the detection and management of iron overload in transfusion-dependent patients with myelodysplastic syndromes (MDS), a 15-min web- or paper-based survey was conducted among 338 European physicians from 27 ...
Fenaux, Pierre, +3 more
core +4 more sources
Metabolically programmed iron chelators [PDF]
Bioorganic & Medicinal Chemistry, 2015 Extensive structure activity relationship (SAR) studies focused on the desferrithiocin [DFT, (S)-4,5-dihydro-2-(3-hydroxy-2-pyridinyl)-4-methyl-4-thiazolecarboxylic acid] pharmacophore have led to three different DFT analogs being evaluated clinically for the treatment of iron overload diseases, for example, thalassemia.
Raymond J, Bergeron +3 more
openaire +2 more sources
Advances in Hematology, 2010 Iron chelation therapy is often used to treat iron overload in patients requiring transfusion of red blood cells (RBC). A 76-year-old man with MDS type refractory cytopenia with multilineage dysplasia, intermediate-1 IPSS risk, was referred when he ...
Maha A. Badawi +3 more
doaj +1 more source
Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]
, 2015 Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa +14 more
core +4 more sources