Results 11 to 20 of about 32,727 (251)
Iron Chelation and Multiple Sclerosis
ASN Neuro, 2014 Histochemical and MRI studies have demonstrated that MS (multiple sclerosis) patients have abnormal deposition of iron in both gray and white matter structures.
Kelsey J. Weigel +2 more
doaj +3 more sources
Iron Chelators in Treatment of Iron Overload
Journal of Toxicology, 2022 Patients suffering from iron overload can experience serious complications. In such patients, various organs, such as endocrine glands and liver, can be damaged. Although iron is a crucial element for life, iron overload can be potentially toxic for human cells due to its role in generating free radicals. In the past few decades, there has been a major
Sarina Entezari +9 more
openaire +3 more sources
Journal of Internal Medicine, 1997 Desferrioxamine (DFX) remains the most effective and safe iron chelator for treatment of patients with transfusional iron overload. It is usually given by intermittent subcutaneous infusions for 8–12 h on 4–6 days weekly using a battery‐driven pump. Disposable balloon infusers provide a suitable method of giving continuous subcutaneous infusions with ...
A V, Hoffbrand, B, Wonke
openaire +2 more sources
Taiwanese Journal of Obstetrics & Gynecology, 2020 Objective: To report cases of use of chelation therapy during pregnancy which resulted in favorable outcomes for the babies. Materials and methods: In this retrospective cohort study, we described the evolution and outcome of 9 pregnancies in Italian ...
Maria Grazia Piccioni +8 more
doaj +1 more source
Predictors of Non-adherence to iron chelation therapy in pediatric thalassemia patients
Journal of Rawalpindi Medical College, 2022 Objective: This study was conducted to identify predictors of non-adherence to iron chelation therapy among children suffering from β-thalassemia major across different treatment regimens.
Muniba Kanwal +3 more
doaj +1 more source
Haematologica, 2012 Background Plasma non-transferrin bound iron refers to heterogeneous plasma iron species, not bound to transferrin, which appear in conditions of iron overload and ineffective erythropoiesis.
Yesim Aydinok +3 more
doaj +1 more source
Frontiers in Pediatrics, 2022 Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed +3 more
doaj +1 more source
Plants, 2023 Iron is essential for numerous biological processes; however, an iron imbalance can contribute to a number of diseases. An excess of iron can accumulate in the body and subsequently induce the production of reactive oxygen species (ROS), leading to ...
Hataichanok Chuljerm +6 more
doaj +1 more source
Advances in Hematology, 2010 Iron chelation therapy is often used to treat iron overload in patients requiring transfusion of red blood cells (RBC). A 76-year-old man with MDS type refractory cytopenia with multilineage dysplasia, intermediate-1 IPSS risk, was referred when he ...
Maha A. Badawi +3 more
doaj +1 more source
Overview of chelation recommendations for thalassaemia and sickle cell disease
Thalassemia Reports, 2014 The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent ...
Banu Kaya
doaj +1 more source