The Role of Iron Chelation Therapy in Colorectal Cancer: A Systematic Review on Its Mechanisms and Therapeutic Potential [PDF]
Cancer MedicineBackground Despite significant therapeutic advancements in recent decades, colorectal cancer (CRC) continues to exhibit high rates of mortality and morbidity.
Gihani Vidanapathirana +4 more
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Advances in iron chelation therapy: transitioning to a new oral formulation [PDF]
Drugs in Context, 2017 Iron overload is a concern for patients who require repeated red-blood-cell transfusions due to conditions such as sickle cell disease, thalassemia, or myelodysplastic syndromes.
Nirmish R Shah
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MYELODYSPLASTIC SYNDROMES AND IRON CHELATION THERAPY [PDF]
Mediterranean Journal of Hematology and Infectious Diseases, 2017 Over recent decades we have been fortunate to witness the advent of new technologies and of an expanded knowledge and application of chelation therapies to the benefit of patients with iron overload.
Emanuele Angelucci +3 more
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New Perspectives in Iron Chelation Therapy for the Treatment of Neurodegenerative Diseases [PDF]
Pharmaceuticals, 2018 Iron chelation has been introduced as a new therapeutic concept for the treatment of neurodegenerative diseases with features of iron overload. At difference with iron chelators used in systemic diseases, effective chelators for the treatment of ...
Marco T. Nuñez, Pedro Chana-Cuevas
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Erythrocytapheresis in Children and Young Adults with Hemoglobinopathies and Iron Overload in Need of Iron Chelation Therapy. [PDF]
J Clin Med, 2023 Limited data regarding erythrocytapheresis in children, adolescents, and young adults have been published. The aim of this study was to evaluate erythrocytapheresis, either as a standalone therapy or in combination with iron chelation therapy, in ...
van Hattem J +5 more
europepmc +4 more sources
Journal of Blood Medicine, 2015 Antoine N Saliba, Afif R Harb, Ali T Taher Department of Internal Medicine, Division of Hematology/Oncology, American University of Beirut, Beirut, Lebanon Abstract: Transfusional iron overload is a major target in the care of patients with transfusion ...
Saliba AN, Harb AR, Taher AT
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Barriers to adherence to iron chelation therapy among adolescent with transfusion dependent thalassemia [PDF]
Frontiers in Pediatrics, 2022 Study backgroundThalassemia is the commonest genetic blood disorder in Malaysia which requires life-long blood transfusions. From a total of 7,984 thalassemia patients in Malaysia, adolescent age group account for the highest number of patients (2,680 ...
Rafaa Mohamed +3 more
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2D-ultrathin MXene/DOXjade platform for iron chelation chemo-photothermal therapy
Bioactive Materials, 2022 An increased demand for iron is a hallmark of cancer cells and is thought necessary to promote high cell proliferation, tumor progression and metastasis. This makes iron metabolism an attractive therapeutic target.
Yunjie Xu +17 more
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A systematic review of adherence to iron chelation therapy among children and adolescents with thalassemia. [PDF]
Ann Med, 2022 Reddy PS, Locke M, Badawy SM.
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Hematology, Transfusion and Cell Therapy, 2023 Introduction: Magnetic resonance imaging (MRI) T2* technique is used to assess iron overload in the heart, liver and pancreas of thalassaemic patients. Optimal iron chelation and expected tissue iron response rates remain under investigation.
Eduardo Cerello Chapchap +17 more
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