Results 31 to 40 of about 65,436 (336)

An Untargeted Metabolomics Approach for Correlating Pulse Crop Seed Coat Polyphenol Profiles with Antioxidant Capacity and Iron Chelation Ability

Molecules, 2021
Pulse crop seed coats are a sustainable source of antioxidant polyphenols, but are typically treated as low-value products, partly because some polyphenols reduce iron bioavailability in humans.
Fatma M. Elessawy, Albert Vandenberg, Anas El-Aneed, Randy W. Purves   +3 more
doaj   +1 more source

Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]

, 2012
This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H., Azimi, R., Baharfar, R., Hellio, Claire, Nabavi, S., Nabavi, S., Zare, M.   +6 more
core   +3 more sources

Overview of chelation recommendations for thalassaemia and sickle cell disease

Thalassemia Reports, 2014
The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent ...
Banu Kaya
doaj   +1 more source

Synthesis and coordination chemistry of 2-(di-2-pyridylamino)pyrimidine; structural aspects of spin crossover in an Fe(II) complex [PDF]

, 2012
This paper was accepted on February 26 20122-(Di-2-pyridylamino)pyrimidine (L), a potentially ditopic tetradentate ligand, was synthesized from commercially available di-2-pyridylamine and 2-chloropyrimidine.
Addison, Amoore, Amoore, Antonioli, Atmani, Balzani, Barbour, Bloch, Boujemma Moubaraki, Brooker, Christopher J. Sumby, Domaga?a, Halcrow, Halcrow, Hayami, Janiak, Kaes, Keith S. Murray, Kharasch, Martin, Mosny, Murray, Murray, Neville, Neville, Olguin, Quesada, Quesada, Quesada, Rachel S. Crees, Real, Real, Ross, Ross, Sheldrick, Sumby, Sumby, Sumby, Sumby   +38 more
core   +2 more sources

Iron Chelation Therapy in Myelodysplastic Syndromes

Advances in Hematology, 2010
Myelodysplastic syndromes (MDS) are a heterogeneous disorder of the hematopoietic stem cells, frequently characterized by anemia and transfusion dependency. In low-risk patients, transfusion dependency can be long lasting, leading to iron overload.
Emanuela Messa, Daniela Cilloni, Giuseppe Saglio   +2 more
doaj   +1 more source

Brazilian Thalassemia Association protocol for iron chelation therapy in patients under regular transfusion

Revista Brasileira de Hematologia e Hemoterapia, 2013
In the absence of an iron chelating agent, patients with beta-thalassemia on regular transfusions present complications of transfusion-related iron overload.
Monica Pinheiro de Almeida Verissimo, Sandra Regina Loggetto, Antonio Fabron Junior, Giorgio Roberto Baldanzi, Nelson Hamerschlak, Juliano Lara Fernandes, Aderson da Silva Araujo, Clarisse Lopes de Castro Lobo, Kleber Yotsumoto Fertrin, Vasilios Antonios Berdoukas, Renzo Galanello   +10 more
doaj   +1 more source

Naringin is a promising natural compound for therapy of iron-overload disorders

Brazilian Journal of Pharmaceutical Sciences, 2022
Naringin has been shown to exhibit satisfying iron chelation capacity. Considering the side effects of routinely-used iron chelator (desferrioxamine, DFO), we decided to evaluate the iron chelation potency of naringin to discover whether or not it can be
Mehrdad Jahanshahi, Masoumeh Khalili, Asra Margdari, Mahdi Aalikhani   +3 more
doaj   +1 more source

Inflammation mobilizes copper metabolism to promote colon tumorigenesis via an IL-17-STEAP4-XIAP axis. [PDF]

, 2020
Copper levels are known to be elevated in inflamed and malignant tissues. But the mechanism underlying this selective enrichment has been elusive. In this study, we report a axis by which inflammatory cytokines, such as IL-17, drive cellular copper ...
Bao, Shideng, Bulek, Katarzyna, Cai, Gang, Chang, Christopher J, Chen, Xing, Fox, Paul L, Huang, Emina, Jackson, Mark W, Jia, Shang, Kalady, Matthew F, Li, Xiaoxia, Liao, Yun, Pizarro, Theresa T, Sen, Ganes C, Stark, George R, Tang, Fangqiang, Zhao, Junjie   +16 more
core  

Challenges of Iron Chelation in Thalassemic Children

Thalassemia Reports
Thalassemia treatment still relies on supportive care, mainly including blood transfusion and iron chelation therapy. Iron chelation is considered the main factor responsible for the marked improvement in survival rates of thalassemic patients ...
Alkistis Adramerina, Marina Economou
doaj   +1 more source

Bistable equilibrium points of mercury body burden [PDF]

, 2007
In the last century mercury levels in the global environment have tripled as a result of increased pollution from industrial, occupational, medicinal and domestic uses \cite{BaMe03}. Glutathione is known to be the main agent responsible for the excretion
Boulos, Areen, Owhadi, Houman
core   +2 more sources