Results 31 to 40 of about 1,030,253 (321)
Plants, 2023 Iron is essential for numerous biological processes; however, an iron imbalance can contribute to a number of diseases. An excess of iron can accumulate in the body and subsequently induce the production of reactive oxygen species (ROS), leading to ...
Hataichanok Chuljerm +6 more
doaj +1 more source
Interferon free antiviral treatment of chronic hepatitis C in patients affected by β-thalassemia major [PDF]
, 2017 Chronic hepatitis C (CHC) significantly affects the prognosis of liver disease [1] and health related quality of life (HRQOL) in patients with β-thalassemia major [2, 3].
Biliotti, Elisa +9 more
core +1 more source
From Iron Chelation to Overload as a Therapeutic Strategy to Induce Ferroptosis in Leukemic Cells
Frontiers in Oncology, 2020 Despite its crucial importance in numerous physiological processes, iron also causes oxidative stress and damage which can promote the growth and proliferation of leukemic cells.
E. Grignano +3 more
semanticscholar +1 more source
Iron Pathways and Iron Chelation Approaches in Viral, Microbial, and Fungal Infections
Pharmaceuticals, 2020 Iron is an essential element required to support the health of organisms. This element is critical for regulating the activities of cellular enzymes including those involved in cellular metabolism and DNA replication.
Ravneet Chhabra +5 more
semanticscholar +1 more source
Iron chelators for acute stroke [PDF]
Cochrane Database of Systematic Reviews, 2011 Stroke is the second leading cause of death and a major cause of morbidity worldwide. Retrospective clinical and animal studies have demonstrated neuroprotective effects of iron chelators in people with haemorrhagic or ischaemic stroke. This is the first update of the original Cochrane Review published in 2012.To evaluate the effectiveness and safety ...
Van der Loo, Lars E. +7 more
openaire +8 more sources
Antioxidant and antihemolytic activities of methanol extract of Hyssopus angustifolius [PDF]
, 2012 This study was designed to evaluate antioxidant and antihemolytic activities of Hyssopus angustifolius flower, stem and leaf methanol extracts by employing various in vitro assays.
Alinezhad, H. +6 more
core +3 more sources
Biological activities and chemical composition of methanolic extracts of selected Autochthonous microalgae strains from the Red Sea [PDF]
, 2015 Four lipid-rich microalgal species from the Red Sea belonging to three different genera (Nannochloris, Picochlorum and Desmochloris), previously isolated as novel biodiesel feedstocks, were bioprospected for high-value, bioactive molecules.
Carolina Bruno De Sousa +14 more
core +4 more sources
Can iron chelation as an adjunct treatment of COVID-19 improve the clinical outcome?
European Journal of Clinical Pharmacology, 2020 A recent bioinformatic study showed that one of the important pathogenic effects of coronavirus disease 2019 (COVID-19) is through the direct damage of haemoglobin molecules by the novel coronavirus (SARS-CoV-2) [1].
Anis Abobaker
semanticscholar +1 more source
Conservative Iron Chelation for Neuroferritinopathy
Movement Disorders, 2022 AbstractBackgroundNeuroferritinopathy is a rare inherited neurodegenerative disease with brain iron accumulation characterized by brain iron overload resulting in progressive movement disorders. No treatment is currently available.ObjectiveWe assessed conservative iron chelation with deferiprone at 30 mg/kg/day on the disease progression with ...
Marchand, Felix +5 more
openaire +3 more sources
Overview of chelation recommendations for thalassaemia and sickle cell disease
Thalassemia Reports, 2014 The long term consequences of iron toxicity are mostly reversible with effective iron chelation therapy. Recommendations for use of chelation therapy in transfusion dependent thalassaemia (TDT), sickle cell disease (SCD) and non transfusion dependent ...
Banu Kaya
doaj +1 more source