Results 231 to 240 of about 1,598,338 (286)

Regulation of brain iron homeostasis and its influence on cognitive function. [PDF]

Eur Radiol
Yoon S, Joo Y, Ha E, Lee S, Suh C, Song Y, Hong H, Shim Y, Kim Y, Lee H, Jeong H, Lim SM, Lyoo IK.   +12 more
europepmc   +1 more source

Iron homeostasis and iron toxicity

, 2001
Crichton, Robert, Ward, Roberta J.
openaire   +1 more source

A Celastrol–Platinum(IV) Nanoprodrug Couples Ferroptosis With Caspase‐Independent Pyroptosis to Enhance Anti‐PD‐1 Therapy in Colorectal Cancer

Advanced Science, EarlyView.
CPAN integrates celastrol‐driven oxidative stress with Pt(IV)‐induced DNA damage to couple ferroptosis with caspase‐independent pyroptosis. Celastrol disrupts the GSH/GPX4 axis and promotes lipid peroxidation, while Pt(IV)‐associated PARP/PARylation signaling facilitates full‐length GSDME oligomerization.
Huirong Li, Wenxiang Feng, Le Xin, Wu Zhong, Zhuhuai Peng, Zhihong Ke, Wenbin Zhou, Yutong Wu, Ying Chen, Hongwei Wang, Jidong Liu, Jinjun Ye, Weihong Guo   +12 more
wiley   +1 more source

Pulmonary neuroendocrine cell-derived exosomes regulate iron homeostasis and oxidative stress in lung neurons. [PDF]

Sci Adv
Thakur A, Zhang K, Chen J, Mei S, Chen J, Verdiell A, Jacobs E, Mulder L, Whitford A, Iyaswamy A, Chen YW, Cliffe A, Esser-Kahn A, Chen B, Lian Q, Solway J, Xing S, Chen HJ.   +17 more
europepmc   +1 more source

Localized Hydrogen Release Driven by Mg–Pd Microgalvanic Cells from 3D‐Printed Microneedles Reverses Redox Homeostasis for Psoriasis Treatment

Advanced Science, EarlyView.
A 3D printing microneedle (MP‐MN), loading magnesium‐based micro‐galvanic cells (MP), is designed for improving psoriasis. H2 generated from MP‐MN scavenges ROS and •OH, actives NRF2‐KEAP1 pathway, and decreases inflammation, thereby effectively restoring the oxidative stress homeostasis of psoriatic skin and suppressing the excessive proliferation of ...
Xinyue Shao, Zongyan He, Ning Yang, Lixuan Yin, Xujie Sun, Jingtong Qi, Xiaolong Feng, Yihui Zhang, Yiran Liu, Zhengwei Huang, Tianqun Lang   +10 more
wiley   +1 more source

Restoring Iron Homeostasis via Smoothened Inhibition: A Novel Strategy Against Hearing Loss. [PDF]

Adv Sci (Weinh)
Mao H, Li X, Liao Y, Liu L, Gao X, Lin H, Ni W, Li H, Chen Y, Li W.   +9 more
europepmc   +1 more source

MicroRNA‐941 Acts as a Novel Prognostic Predictor and Oncogenic Driver in Colorectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
Upregulation of miR‐941 was a promising diagnostic and prognostic biomarker for CRC patients. Inhibition of miR‐941 significantly suppressed CRC cellular events and triggered ferroptosis. The oncogenic functions of miR‐941 were mediated through targeting TRPS1.
Hong Li, Yang Liu, Hua Chen, Jialin Li, Xinchun Li, Yanmin Chen   +5 more
wiley   +1 more source

The Potential Role of Iron Homeostasis and Ferroptosis in Exercise Nutrition and Health. [PDF]

Nutrients
Wang Q, Gao R, Zhu K, Qiu H, Huang J, Zhang X.   +5 more
europepmc   +1 more source

Preoperative Total Iron‐Binding Capacity Is a Potential Surrogate Marker of Long‐Term Outcomes After Pancreatectomy for Pancreatic Cancer

Annals of Gastroenterological Surgery, EarlyView.
Preoperative low serum total iron‐binding capacity (TIBC) was associated with poorer overall survival and recurrence‐free survival after pancreatectomy for pancreatic cancer. These findings suggest that preoperative serum TIBC may serve as a simple surrogate marker for long‐term outcomes in patients undergoing pancreatectomy.
Taishi Yamane, Hiromitsu Hayashi, Hiroshi Sawayama, Takashi Matsumoto, Toru Takematsu, Takanobu Yamao, Yuki Kitano, Tatsunori Miyata, Hirohisa Okabe, Masaaki Iwatsuki   +9 more
wiley   +1 more source

Duration-Dependent Aerobic Exercise Attenuates HFD-Induced MASLD in Association with Improved Hepatic Iron Homeostasis and Reduced Ferroptosis-Related Alterations. [PDF]

Metabolites
Xu L, Li C, Liu Y, Wang S.
europepmc   +1 more source