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Iron metabolism [PDF]

open access: yesEinstein (São Paulo), 2005
The present paper deals with iron metabolism, from its absorption,regulatory factors, storage, and distribution to body compartmentsaccording to existing knowledge.
Ana Maria de Souza
doaj   +1 more source

Role of the irr protein in the regulation of iron metabolism in Rhodobacter sphaeroides [PDF]

open access: yes, 2012
In Rhizobia the Irr protein is an important regulator for iron-dependent gene expression. We studied the role of the Irr homolog RSP_3179 in the photosynthetic alpha-proteobacterium Rhodobacter sphaeroides.
Klug, Gabriele   +2 more
core   +11 more sources

Rhabdomyolysis after Intravenous Ferric Gluconate: A Case Report

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2022
Patients with severe iron deficiency, malabsorption or intolerance to oral iron are frequently treated with intravenous iron replacement. We report the case of a 42-year-old woman with non-erosive oligoarticular arthritis with antiparietal cell ...
Mara Botti   +3 more
doaj   +1 more source

The emerging role of furin in neurodegenerative and neuropsychiatric diseases

open access: yesTranslational Neurodegeneration, 2022
Furin is an important mammalian proprotein convertase that catalyzes the proteolytic maturation of a variety of prohormones and proproteins in the secretory pathway.
Yi Zhang   +5 more
doaj   +1 more source

Iron metabolism and iron disorders revisited in the hepcidin era

open access: yesHaematologica, 2020
Iron is biologically essential, but also potentially toxic; as such it is tightly controlled at cell and systemic levels to prevent both deficiency and overload.
Clara Camaschella   +2 more
doaj   +1 more source

PKAN hiPS-Derived Astrocytes Show Impairment of Endosomal Trafficking: A Potential Mechanism Underlying Iron Accumulation

open access: yesFrontiers in Cellular Neuroscience, 2022
PKAN disease is caused by mutations in the PANK2 gene, encoding the mitochondrial enzyme pantothenate kinase 2, catalyzing the first and key reaction in Coenzyme A (CoA) biosynthetic process.
Maddalena Ripamonti   +8 more
doaj   +1 more source

COBALAMIN DEFICIENCY IN THE ELDERLY

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2020
Older people are at risk for cobalamin (vitamin B12) deficiency because of a number of common disorders (e.g. autoimmune gastritis) and drugs (e.g. antacids) that may alter its absorption and utilization.
Giacomo Marchi   +4 more
doaj   +1 more source

Mitochondrial ferritin alleviates apoptosis by enhancing mitochondrial bioenergetics and stimulating glucose metabolism in cerebral ischemia reperfusion

open access: yesRedox Biology, 2022
Oxidative stress and deficient bioenergetics are key players in the pathological process of cerebral ischemia reperfusion injury (I/R). As a mitochondrial iron storage protein, mitochondrial ferritin (FtMt) plays a pivotal role in protecting neuronal ...
Peina Wang   +6 more
doaj   +1 more source

Iron economy in Chlamydomonas reinhardtii. [PDF]

open access: yes, 2013
While research on iron nutrition in plants has largely focused on iron-uptake pathways, photosynthetic microbes such as the unicellular green alga Chlamydomonas reinhardtii provide excellent experimental systems for understanding iron metabolism at the ...
Blaby-Haas, Crysten E   +2 more
core   +1 more source

Circulating iron levels influence the regulation of hepcidin following stimulated erythropoiesis

open access: yesHaematologica, 2018
The stimulation of erythrocyte formation increases the demand for iron by the bone marrow and this in turn may affect the levels of circulating diferric transferrin.
Cornel S.G. Mirciov   +5 more
doaj   +1 more source

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