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Relationship between physical activity and health-related indicators of iron metabolism: evidence from a large, representative cohort. [PDF]
Arch Med SciWang Z, Wang Y.
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Current Opinion in Chemical Biology, 1999
The understanding of iron metabolism at the molecular level has been enormously expanded in recent years by new findings about the functioning of transferrin, the transferrin receptor and ferritin. Other recent developments include the discovery of the hemochromatosis gene HFE, identification of previously unknown proteins involved in iron transport ...
P, Aisen +2 more
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The understanding of iron metabolism at the molecular level has been enormously expanded in recent years by new findings about the functioning of transferrin, the transferrin receptor and ferritin. Other recent developments include the discovery of the hemochromatosis gene HFE, identification of previously unknown proteins involved in iron transport ...
P, Aisen +2 more
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Seminars in Pediatric Neurology, 2006
Brain iron uptake is regulated by the expression of transferrin receptor 1 in endothelial cells of the blood-brain barrier. Transferrin-bound iron in the systemic circulation is endocytosed by brain endothelial cells, and elemental iron is released to brain interstitial fluid, likely by the iron exporter, ferroportin.
Tracey A, Rouault, Sharon, Cooperman
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Brain iron uptake is regulated by the expression of transferrin receptor 1 in endothelial cells of the blood-brain barrier. Transferrin-bound iron in the systemic circulation is endocytosed by brain endothelial cells, and elemental iron is released to brain interstitial fluid, likely by the iron exporter, ferroportin.
Tracey A, Rouault, Sharon, Cooperman
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Seminars in Liver Disease, 2005
The liver performs three main functions in iron homeostasis. It is the major site of iron storage, it regulates iron traffic into and around the body through its production of the peptide hepcidin, and it is the site of synthesis of major proteins of iron metabolism such as transferrin and ceruloplasmin.
Gregory J, Anderson, David M, Frazer
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The liver performs three main functions in iron homeostasis. It is the major site of iron storage, it regulates iron traffic into and around the body through its production of the peptide hepcidin, and it is the site of synthesis of major proteins of iron metabolism such as transferrin and ceruloplasmin.
Gregory J, Anderson, David M, Frazer
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La Revue du praticien, 2007
Iron is required for proper cell life functioning. Iron metabolism dysfunction leads in humans to deleterious situations. Maintenance of correct iron plasmatic bioavailability is crucial to permit adequate iron addressing to the different cell types.
Olivier, Loréal +5 more
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Iron is required for proper cell life functioning. Iron metabolism dysfunction leads in humans to deleterious situations. Maintenance of correct iron plasmatic bioavailability is crucial to permit adequate iron addressing to the different cell types.
Olivier, Loréal +5 more
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Epidermal iron metabolism for iron salvage
Journal of Dermatological Science, 2017The epidermis shows a reverse iron gradient from the basal layer to the stratum corneum and consequently, little epidermal intracellular iron is lost by desquamation.To clarify the underlying mechanism of iron salvage.We first used immunohistochemistry and mRNA quantification to demonstrate the distinctive expression pattern of iron metabolism ...
Masayuki, Asano +4 more
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Pediatrics, 1956
THE CLINICIAN has long been aware of the fact that iron deficiency anemia is most prevalent during infancy. Continuing studies of iron metabolism have disclosed many factors which help explain the basic mechanisms of the anemia and the peculiar vulnerability of the infant.
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THE CLINICIAN has long been aware of the fact that iron deficiency anemia is most prevalent during infancy. Continuing studies of iron metabolism have disclosed many factors which help explain the basic mechanisms of the anemia and the peculiar vulnerability of the infant.
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Toxicology Mechanisms and Methods, 2007
ABSTRACT Iron is an essential transition metal for mammalian cellular and tissue viability. It is critical to supplying oxygen through heme, the mitochondrial respiratory chain, and enzymes such as ribonucleotide reductase. Mammalian organisms have evolved with the means of regulating the metabolism of iron, because if left unregulated, the resulting ...
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ABSTRACT Iron is an essential transition metal for mammalian cellular and tissue viability. It is critical to supplying oxygen through heme, the mitochondrial respiratory chain, and enzymes such as ribonucleotide reductase. Mammalian organisms have evolved with the means of regulating the metabolism of iron, because if left unregulated, the resulting ...
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Iron Metabolism: Iron Deficiency and Iron Overload
Annual Review of Genomics and Human Genetics, 2000Iron is an essential cofactor in a variety of cellular processes. Except for a few unusual bacterial species, iron is indispensable for living organisms. However, free iron is toxic because of its propensity to induce the formation of dangerous free radicals. Consequently, iron balance is tightly regulated.
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Metabolomics in cancer research and emerging applications in clinical oncology
Ca-A Cancer Journal for Clinicians, 2021Daniel R Schmidt +2 more
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