Results 21 to 30 of about 479,648 (301)
Cellular iron metabolism [PDF]
Kidney International, 1999 Iron is essential for oxidation-reduction catalysis and bioenergetics, but unless appropriately shielded, iron plays a key role in the formation of toxic oxygen radicals that can attack all biological molecules. Hence, specialized molecules for the acquisition, transport (transferrin), and storage (ferritin) of iron in a soluble nontoxic form have ...
openaire +2 more sources
Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis [PDF]
, 2018 Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood.
Camacho, António +7 more
core +4 more sources
Iron metabolism of intestinal mucosa in various blood diseases [PDF]
, 1964 For the investigation of iron metabolism in the intestinal mucosa in various blood diseases, intestinal biopsy (duodenum) was performed on 10 healthy controls and 35 cases with various blood diseases.
Kimura, Ikuro +2 more
core +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2018 Background & Aims: Multicopper ferroxidases (MCFs) facilitate intestinal iron absorption and systemic iron recycling, likely by a mechanism involving the oxidization of Fe2+ from the iron exporter ferroportin 1 for delivery to the circulating Fe3 ...
Brie K. Fuqua +12 more
doaj +1 more source
Frontiers in Physiology, 2020 Iron loading anemias are characterized by ineffective erythropoiesis and iron overload. The prototype is non-transfusion dependent ß-thalassemia (NTDT), with other entities including congenital sideroblastic anemias, congenital dyserythropoietic anemias,
Acaynne Lira Zidanes +17 more
doaj +1 more source
Iron metabolism in human body and its regulatory factors [PDF]
Jichu yixue yu linchuang, 2022 This article reviews the molecular mechanism of iron metabolism covering iron absorption,transportation,utilization and storage with focus on the key proteins involved in iron metabolism and elaborate regulation factors.
CHEN Chun-mei, GE Pin, GUO Chong
doaj +1 more source
Iron Deficiency in Infancy and Its Impact on Motor and Mental Development [PDF]
, 2020 Iron plays a large role in nerve myelination, dopamine neurotransmission, and neuronal metabolism. The purpose of this literary review was to investigate the connection between iron deficiency and motor and cognitive development.
Baker, Emma
core +1 more source
Cell Death and Disease, 2023 Ischemic stroke is associated with high mortality and morbidity rates worldwide. However, the molecular mechanisms underlying the neuronal damage incurred by stroke victims remain unclear.
Huiwen Zheng +9 more
doaj +1 more source
Iron Metabolism: From Health to Disease [PDF]
, 2014 Background Iron is vital for almost all living organisms by participating in a wide range of metabolic processes. However, iron concentration in body tissues must be tightly regulated since excessive iron may lead to microbial infections or cause tissue
Fernandes, Rúben +2 more
core +1 more source
Pyoverdine and proteases affect the response of pseudomonas aeruginosa to gallium in human serum [PDF]
, 2015 Gallium is an iron mimetic which has recently been repurposed as an antibacterial agent due to its capability to disrupt bacterial iron metabolism. In this study, the antibacterial activity of gallium nitrate [Ga(NO3)3] was investigated in complement ...
Bonchi, Carlo +3 more
core +1 more source