Results 21 to 30 of about 90,175 (271)
Pathogenetic aspects of hepcidin metabolism and ferrocinetics dysregulation in carbohydrate metabolism disorders [PDF]
Сахарный диабет, 2018 Hepcidin, a hormone regulating iron metabolism, has received attention for its role in the pathogenesis of dysregulations in carbohydrate metabolism. Hepcidin disorders in patients with diabetes mellitus are bi-directional: manifesting as iron overload ...
Tatiana V. Saprina +6 more
doaj +2 more sources
The Role of Iron in the Pathogenesis of Autism Spectrum Disorders in Children
Вопросы современной педиатрии, 2018 The review presents an analysis of the mechanisms of iron effect on the brain development. The importance of iron deficiency in the perinatal period is considered as a risk factor for the development of neuropsychiatric disorders in children with autism ...
Olga V. Kostina
doaj +3 more sources
Stress-Induced Dysregulation of Brain Iron Metabolism and Its Links to Neurological Disorders
BiologyStress is a non-specific systemic response to internal or external challenges. Recent studies show that stress can disrupt iron metabolism and that iron dyshomeostasis is implicated in many diseases-particularly within the nervous system, where iron ...
Ke Dong +6 more
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Crosstalk between Iron Metabolism and Erythropoiesis [PDF]
Advances in Hematology, 2010 Iron metabolism and erythropoiesis are inextricably linked. The majority of iron extracted from circulation daily is used for hemoglobin synthesis.
Huihui Li, Yelena Z. Ginzburg
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Iron metabolism in aging and age-related diseases [PDF]
, 2022 Iron is a trace metal element necessary to maintain life and is also involved in a variety of biological processes. Aging refers to the natural life process in which the physiological functions of the various systems, organs, and tissues decline ...
Shuai Wang +15 more
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Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy
Nature Communications, 2021 Iron is essential during pregnancy for embryo and placental development and maternal health. However, in this study using mouse models, the authors demonstrate that excess maternal iron causes adverse embryo outcomes in pregnancies with underlying ...
Allison L. Fisher +5 more
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Frontiers in Physiology, 2020 Iron loading anemias are characterized by ineffective erythropoiesis and iron overload. The prototype is non-transfusion dependent ß-thalassemia (NTDT), with other entities including congenital sideroblastic anemias, congenital dyserythropoietic anemias,
Acaynne Lira Zidanes +17 more
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, 2022 Iron homeostasis disruption has increasingly been implicated in various neurological disorders. In this review, we present an overview of our current understanding of iron metabolism in the central nervous system. We examine the consequences of both iron
Porras, Christina A. +3 more
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Frontiers in Neurology, 2022 Background and purposeIron metabolism in myasthenia gravis (MG) and factors associated with it are explored by few published studies. Therefore, this study aimed to compare iron metabolism patterns between patients with MG and healthy individuals as well
Ke Li +7 more
doaj +1 more source
The role of iron in neurodegenerative disorders : insights and opportunities with synchrotron light [PDF]
, 2014 There is evidence for iron dysregulation in many forms of disease, including a broad spectrum of neurodegenerative disorders. In order to advance our understanding of the pathophysiological role of iron, it is helpful to be able to determine in detail ...
Mark R. Davidson +3 more
core +1 more source