Results 11 to 20 of about 12,385 (205)

5-(Trifluoromethoxy)isatin [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The
M. Schutte   +3 more
openaire   +3 more sources

Encapsulation of an anticancer drug Isatin inside a host nano-vehicle SWCNT: a molecular dynamics simulation

open access: yesScientific Reports, 2021
The use of carbon nanotubes as anticancer drug delivery cargo systems is a promising modality as they are able to perforate cellular membranes and transport the carried therapeutic molecules into the cellular components.
Maryam Zarghami Dehaghani   +10 more
doaj   +1 more source

Synthesis of substituted isatins [PDF]

open access: yesTetrahedron Letters, 2013
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Larry L, Klein, Michael D, Tufano
openaire   +2 more sources

Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2013
An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A.   +2 more
doaj   +1 more source

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

open access: yesAntioxidants, 2022
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik   +6 more
doaj   +1 more source

Corrosion and Inhibition of Cu-Zn Alloys in Acidic Medium by Using Isatin

open access: yesInternational Journal of Electrochemical Science, 2008
The effect of isatin on the corrosion of Cu-Zn alloys in H2SO4 and HCl solution has been studied using open circuit potential, potentiodynamic, and electrochemical impedance spectroscopy (EIS) techniques.
S. A. M. Refaey, A. M. Abd El Malak, F. Taha and H. T. M. Abdel-Fatah
doaj   +2 more sources

Microwave assisted synthesis and antimicrobial activity of 2-quinoxalinone-3-hydrazone derivatives [PDF]

open access: yes, 2010
A simple and efficient method has been developed for the synthesis of various 2-quinoxalinone-3-hydrazone derivatives using microwave irradiation technique. The series of 2-quinoxalinone-3-hydrazone derivatives synthesized, were structurally confirmed by
Ajani, Olayinka O.
core   +1 more source

Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]

open access: yes, 2002
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Casey, Lorraine A.   +4 more
core   +1 more source

Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer [PDF]

open access: yes, 2018
Background: Effective anticancer therapy is thought to involve induction of tumour cell death through apoptosis and/or necrosis. [18F]ICMT-11, an isatin sulfonamide caspase-3/7-specific radiotracer, has been developed for PET imaging and shown to have ...
Aboagye, Eric O.   +16 more
core   +1 more source

Effect of Structure on Charge Distribution in the Isatin Anions in Aprotic Environment: Spectral Study

open access: yesMolecules, 2017
Five isatin anions were prepared by deprotonation of initial isatins in aprotic solvents using basic fluoride and acetate anions (F− and CH3COO−). The F− basicity is sufficient to deprotonate isatin NH hydrogen from all the studied compounds.
Pavol Tisovský   +9 more
doaj   +1 more source

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