Results 11 to 20 of about 7,251 (220)

Synthesis and Preliminary Antimicrobial Analysis of Isatin–Ferrocene and Isatin–Ferrocenyl Chalcone Conjugates [PDF]

ACS Omega, 2018
In this study, we outline the synthesis of isatin-ferrocenyl chalcone and 1H-1,2,3-triazole-tethered isatin-ferrocene conjugates along with their antimicrobial evaluation against the human mucosal pathogen Trichomonas vaginalis. The introduction of a triazole ring among the synthesized conjugates improved the activity profiles with most of the ...
Amandeep Singh, Grant Fong, Jenny Liu, Yun-Hsuan Wu, Kevin Chang, William Park, Jihwan Kim, Christina Tam, Luisa W. Cheng, Kirkwood M. Land, Vipan Kumar   +10 more
openaire   +5 more sources

SYNTHESIS, X-RAY AND ANTIMICROBIAL ACTIVITY OF ISATIN-3-PHENYLHYDRAZONE [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2008
Isatin-3-phenylhydrazone was synthesized and X-ray crystal structure of this compound has been solved. Its structure was also established using FTIR, UV/Vis and 1H-NMR spectroscopic method.
SANDRA S. KONSTANTINOVIĆ, AGNEŠ KAPOR, BLAGA C. RADOVANOVIĆ, ANDREA DEAK   +3 more
doaj   +1 more source

Condensation of Indole with Isatin over AlCl₃/Mesoporous Aluminosilicate

Indonesian Journal of Chemistry, 2015
Aluminium chloride immobilized on mesoporous aluminosilicate was investigated as catalysts in the condensation of isatin with indole. AlCl3/mesoporous aluminosilicate (AlCl3/AM) catalysts were prepared by impregnation of 1, 5, 10 and 15 wt% AlCl3 on the ...
Tri Esti Purbaningtias, Didik Prasetyoko, Hasliza Bahruji, Yusuf Muhammad Zein, Sugeng Triwahyono, Arief Fadlan, Imroatul Qoniah   +6 more
doaj   +3 more sources

Ultrasound-Assisted Synthesis and Comprehensive Characterization of Nanosized VO(II), Fe(III), and Ru(III) Complexes: From Density Functional Theory/Nonlinear Optical Properties to Pharmaceutical Applications and Docking Insights. [PDF]

ChemistryOpen
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
El-Kasaby RA, Al-Farraj ES, Akkoc S, Alsehli AH, Fathalla M, Abdel-Latif SA, Alghamdi MA, Abu-Dief AM.   +7 more
europepmc   +2 more sources

Synthesis of substituted isatins [PDF]

Tetrahedron Letters, 2013
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Larry L, Klein, Michael D, Tufano
openaire   +2 more sources

5-(Trifluoromethoxy)isatin [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The
M. Schutte, C. Pretorius, H.G. Visser, A. Roodt   +3 more
openaire   +3 more sources

Corrosion and Inhibition of Cu-Zn Alloys in Acidic Medium by Using Isatin

International Journal of Electrochemical Science, 2008
The effect of isatin on the corrosion of Cu-Zn alloys in H2SO4 and HCl solution has been studied using open circuit potential, potentiodynamic, and electrochemical impedance spectroscopy (EIS) techniques.
S.A.M. Refaey, A. M. Abd El Malak, F. Taha, H.T.M. Abdel-Fatah   +3 more
doaj   +2 more sources

Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A., Siddiqui Masoom R., Wabaidur Saikh M.   +2 more
doaj   +1 more source

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Antioxidants, 2022
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik, Wafaa R. Mohamed, Hanan S. Mahmoud, Mohammed A. Alqarni, Ibrahim A. Naguib, Alzhraa M. Fahmy, Osama M. Ahmed   +6 more
doaj   +1 more source

Evaluation of Anti-Neuroinflammatory Activity of Isatin Derivatives in Activated Microglia [PDF]

, 2023
Neuroinflammation plays a crucial role in the progression of Alzheimer’s disease and other neurodegenerative disorders. Overactivated microglia cause neurotoxicity and prolong the inflammatory response in many neuropathologies.
Alejandro Cenalmor, José Ramón Suárez, García Álvarez, Isabel, Pascual, Elena, Isabel García-Álvarez, Cenalmor Molina, Alejandro, Cenalmor, Alejandro, Ramón Suárez, José, Elena Pascual, Pascual Vega, Elena, Rafael Correa-Rocha, Gil-Manso, Sergio, Sergio Gil-Manso, García-Álvarez, Isabel, Correa-Rocha, Rafael, Suárez Álvarez, José Ramón, Suárez, José Ramón   +16 more
core   +1 more source