Results 11 to 20 of about 4,322 (180)

Ultrasound-Assisted Synthesis and Comprehensive Characterization of Nanosized VO(II), Fe(III), and Ru(III) Complexes: From Density Functional Theory/Nonlinear Optical Properties to Pharmaceutical Applications and Docking Insights. [PDF]

open access: yesChemistryOpen
Ultrasound‐assisted synthesis enabled the formation of ultrafine hydrazone‐based metal complexes with controlled nanostructures and enhanced stability. Density functional theory revealed optimized geometries and electronic properties. The nanosized complexes exhibited superior antimicrobial, anticancer, and antioxidant activities, supported by ...
El-Kasaby RA   +7 more
europepmc   +2 more sources

5-(Trifluoromethoxy)isatin [PDF]

open access: yesActa Crystallographica Section E Structure Reports Online, 2012
THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(trifluoro-meth-oxy)-1H-indole-2,3-dione], C9H4F3NO3, crystallized with two mol-ecules in the asymmetric unit. Inter-molecular N-H⋯O hydrogen bonds link the mol-ecules to form layers parallel to the ab plane. In addition, π-π stacking inter-actions are observed with a centroid-centroid distance of 3.721 (1) Å. The
M. Schutte   +3 more
openaire   +3 more sources

Synthesis of substituted isatins [PDF]

open access: yesTetrahedron Letters, 2013
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Larry L, Klein, Michael D, Tufano
openaire   +2 more sources

Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]

open access: yesChemical Industry and Chemical Engineering Quarterly, 2013
An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A.   +2 more
doaj   +1 more source

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

open access: yesAntioxidants, 2022
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik   +6 more
doaj   +1 more source

A Mini Review on Isatin, an Anticancer Scaffold with Potential Activities against Neglected Tropical Diseases (NTDs)

open access: yesPharmaceuticals, 2022
Isatin, chemically an indole-1H-2,3-dione, is recognised as one of the most attractive therapeutic fragments in drug design and development. The template has turned out to be exceptionally useful for developing new anticancer scaffolds, as evidenced by ...
Shefali Chowdhary   +3 more
doaj   +1 more source

Effect of Structure on Charge Distribution in the Isatin Anions in Aprotic Environment: Spectral Study

open access: yesMolecules, 2017
Five isatin anions were prepared by deprotonation of initial isatins in aprotic solvents using basic fluoride and acetate anions (F− and CH3COO−). The F− basicity is sufficient to deprotonate isatin NH hydrogen from all the studied compounds.
Pavol Tisovský   +9 more
doaj   +1 more source

The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats

open access: yesBMC Neuroscience, 2002
Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) have hyperthermic properties.
Tóth Gábor   +4 more
doaj   +1 more source

The influence of Schiff base inclusion complexes with β-cyclodextrine on antibiotic production by Streptomyces hygroscopicus CH-7 [PDF]

open access: yesHemijska Industrija, 2015
A media consisting of isatin-Schiff bases and its inclusion complexes with β-cyclodextrine was developed to maximize the production of antibiotics Hexaene H-85 and Azalomycine β by Streptomyces hygroscopicus CH-7.
Ilić Slavica B.   +4 more
doaj   +1 more source

EFFECT OF SOME GROWTH REGULATORS ON SQUASH GROWTH, YIELD AND CHEMICAL CONTENTS [PDF]

open access: yesJournal of Plant Production, 2007
The present study was conducted on squash plants during the summer of 2006 and 2007 seasons at the Experimental Farm, Faculty of Agriculture, Suez CanalUniversity, Ismailia governorate to study the effects of foliar spray with vit.
M. Elwan, H. Hossien,
doaj   +1 more source

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