Results 11 to 20 of about 8,195 (166)

SYNTHESIS, X-RAY AND ANTIMICROBIAL ACTIVITY OF ISATIN-3-PHENYLHYDRAZONE [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2008
Isatin-3-phenylhydrazone was synthesized and X-ray crystal structure of this compound has been solved. Its structure was also established using FTIR, UV/Vis and 1H-NMR spectroscopic method.
SANDRA S. KONSTANTINOVIĆ, AGNEŠ KAPOR, BLAGA C. RADOVANOVIĆ, ANDREA DEAK   +3 more
doaj   +1 more source

Synthesis of isatin, 5-chloroisatin and their 2-1,3,4 oxadiazoline derivatives for comparative cytotoxicity study on brine shrimp

Bangladesh Journal of Pharmacology, 2007
Isatin (3a), isatin 3-carbohydrazone (4a), 5-spiro (isatin) 2-(N-acetyl hydrazino) 4-(N-acetyl)-2-1,3,4 oxadiazoline (5a), and 5-spiro (isatin) 2-hydrazino-2-1,3,4 oxadiazoline (6a) have been synthesized from unsubstituted oximinoacetanilide (2a).
Md. Rabiul Islam and Mohammad Mohsin
doaj   +1 more source

Estimation of isatin in spiked plasma samples using high performance liquid chromatography [PDF]

Chemical Industry and Chemical Engineering Quarterly, 2013
An isocratic analytical method based on liquid chromatographic determination with UV detection is described for the determination of isatin in spiked plasma and in its synthetic mixture.
Alothman Zeid A., Siddiqui Masoom R., Wabaidur Saikh M.   +2 more
doaj   +1 more source

Design, Synthesis, and Biological Evaluation of Molecular Hybrids Incorporating Coumarin-Pyrazole-Linked Indolinone Derivatives With Antioxidant and Anti-Alzheimer Properties. [PDF]

Chem Biodivers
ABSTRACT The increase in global life expectancy has resulted in a significant rise in the occurrence of Alzheimer's disease (AD), making it a critical public health burden. Therefore, there is an urgent need to create effective methods to prevent or slow down the progression of the disease.
Sabt A, Aboulthana WM, Saleh AM, Ibrahim HAA, Saleh A, Lei X, Srour AM.   +6 more
europepmc   +2 more sources

Corrosion and Inhibition of Cu-Zn Alloys in Acidic Medium by Using Isatin

International Journal of Electrochemical Science, 2008
The effect of isatin on the corrosion of Cu-Zn alloys in H2SO4 and HCl solution has been studied using open circuit potential, potentiodynamic, and electrochemical impedance spectroscopy (EIS) techniques.
S. A. M. Refaey, A. M. Abd El Malak, F. Taha and H. T. M. Abdel-Fatah
doaj   +2 more sources

Isatin Counteracts Diethylnitrosamine/2-Acetylaminofluorene-Induced Hepatocarcinogenesis in Male Wistar Rats by Upregulating Anti-Inflammatory, Antioxidant, and Detoxification Pathways

Antioxidants, 2022
Hepatocellular carcinoma (HCC) represents around 85% of all known types of liver cancers and is estimated to be the fifth most common cause of cancer-related death worldwide.
Nagwa G. Tawfik, Wafaa R. Mohamed, Hanan S. Mahmoud, Mohammed A. Alqarni, Ibrahim A. Naguib, Alzhraa M. Fahmy, Osama M. Ahmed   +6 more
doaj   +1 more source

Effect of Structure on Charge Distribution in the Isatin Anions in Aprotic Environment: Spectral Study

Molecules, 2017
Five isatin anions were prepared by deprotonation of initial isatins in aprotic solvents using basic fluoride and acetate anions (F− and CH3COO−). The F− basicity is sufficient to deprotonate isatin NH hydrogen from all the studied compounds.
Pavol Tisovský, Róbert Šandrik, Miroslav Horváth, Jana Donovalová, Klaudia Jakusová, Marek Cigáň, Róbert Sokolík, Anton Gáplovský, Martin Gáplovský, Juraj Filo   +9 more
doaj   +1 more source

The effects of isatin (indole-2, 3-dione) on pituitary adenylate cyclase-activating polypeptide-induced hyperthermia in rats

BMC Neuroscience, 2002
Background Previous studies have demonstrated that centrally administered natriuretic peptides and pituitary adenylate cyclase-activating polypeptide-38 (PACAP-38) have hyperthermic properties.
Tóth Gábor, Glover Vivette, Adamik Ágnes, Pataki Imre, Telegdy Gyula   +4 more
doaj   +1 more source

Advances in Pharmacology of Isatin and its Derivatives: A Review [PDF]

, 2015
Isatin (1H-indole-2,3-dione), an indole derivative of plant origin, is involved in many pharmacological activities like antiallergic, antimalarial, antiviral and antimicrobial; isatin and its derivatives have been found to show promising results against ...
Maalik, Aneela, Khan, Farhan A
core   +1 more source

Effect of Substituents on the Biological Activity of Isatin Hybrids – A SAR Study

, 2023
: Isatin (2,3-dioxindole) is a benzopyrrole derivative that belongs to a large class of heterocyclic chemicals. Isatin derivatives are essential synthetic substrates that can be utilized as starting materials to build a wide range of heterocycles with ...
Sakshi Soam, Sreela Dasgupta
core   +1 more source