Results 61 to 70 of about 17,152 (250)

Urea derivative organocatalyzed enantioselective Friedel–Crafts alkylation of α‐naphthols with isatins [PDF]

, 2022
Liming Wang, Zhe Chen, Huiting Jiang, Jie Zhang, Ying Jin   +4 more
openalex   +1 more source

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives

Journal of Chemistry, 2015
Three series of isatin derivatives [3-hydrazino, 3-thiosemicarbazino, and 3-imino carboxylic acid derivatives] were synthesized employing microwave irradiation.
Ayman El-Faham, Wael N. Hozzein, Mohammad A. M. Wadaan, Sherine N. Khattab, Hazem A. Ghabbour, Hoong-Kun Fun, Mohammed Rafiq Siddiqui   +6 more
doaj   +1 more source

Next‐Generation Proteolysis‐Targeting Chimeras in Precision Oncology: Multifunctional Designs, Emerging Modalities, and Translational Prospects in Targeted Protein Degradation

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Proteolysis‐targeting chimeras (PROTACs)‐mediated protein degradation has been recently developed as a game‐changing approach in oncology drug development. It represents a paradigm shift from traditional enzyme inhibition to selective protein degradation.
Mohamed S. Nafie, Mohamed K. Diab, Asmaa S. A. Yassen, Amany M. Elshamy, Mohamed R. El Tohamy, Haytham O. Tawfik, Sherif Ashraf Fahmy   +6 more
wiley   +1 more source

Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]

, 2016
This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima, Lassaletta, José M., Matador Martínez, Esteban, Monge Fernández, David, Retamosa Hernández, María Gracia   +4 more
core   +1 more source

Azide–Alkyne Cycloaddition En Route to 1H-1,2,3-Triazole-Tethered Isatin–Ferrocene, Ferrocenylmethoxy–Isatin, and Isatin–Ferrocenylchalcone Conjugates: Synthesis and Antiproliferative Evaluation [PDF]

ACS Omega, 2018
Diverse series of isatin-ferrocene conjugates were synthesized via Cu-promoted azide-alkyne cycloaddition reaction with an aim of probing their antiproliferative structure-activity relationship against MCF-7 (estrogen receptor positive) and MDA-MB-231 (triple negative) cell lines.
Amandeep Singh, Sourav Taru Saha, Shanen Perumal, Mandeep Kaur, Vipan Kumar   +4 more
openaire   +3 more sources

Synthesis of Poly(p‐Terphenyl N,N‐Dimethylpiperidinium)s Using Asymmetric Ketone‐Based Branching Agent

Macromolecular Materials and Engineering, Volume 310, Issue 12, December 2025.
4‐Biphenylyl trifluoromethyl ketone is used as an asymmetric branching agent in the synthesis of aryl ether‐free poly(p‐terphenyl‐N,N‐dimethylpiperidinium)s via optimized superacid‐catalyzed Friedel‐Crafts polyhydroxyalkylation. The resulting quaternized polymers, with varying branching degrees, show high molecular weights (∼70 kDa) as determined by ...
Ihor Tkachenko, Tetiana Samoilenko, Mariana Gumenna, David Kalabis, Ruslan Kravchuk, Vassili Nazarenko, Iva Matolínová, Valery Shevchenko   +7 more
wiley   +1 more source

Synthesis and fluorine-mediated interactions in methanol-encapsulated solid state self-assembly of an isatin-thiazoline hybrid

, 2015
International audienceAn exciting isatin-thiazoline hybrid molecule 2 having -C=N-N=C- linkage has been synthesized in 88% yield by the reaction of 5-fluoroisatin with N-(4-fluorophenyl)hydrazinecarbothioamide followed by condensation of the resultant ...
Ahmad, Maqbool, Hadda, Taibi B., Naseer, Muhammad Moazzam, Pervez, Humayun, Toupet, Loic   +4 more
core   +2 more sources

Chiral Quaternary Ammoniums Derived from Dehydroabietylamine: Synthesis and Application to Alkynylation of Isatin Derivatives Catalyzed by Silver [PDF]

, 2021
Guanyu Jiang, Xinduo Sun, Fanrui Zhou, Kun Liang, Qian Chen   +4 more
openalex   +1 more source

Chemistry, Applications, and Synthesis Methods of Indole Derivatives: A Comprehensive Review

The Chemical Record, Volume 25, Issue 12, December 2025.
Indole and its derivatives represent a vital class of heterocycles with broad applications in pharmaceuticals, agrochemicals, and materials science. This review explores their applications, biosynthesis, key derivatives such as tryptophan, and presents an overview of both classical and modern synthetic methodologies, with a focus on sustainable ...
Raphael Silva Moratório de Moraes, Ana Beatriz Mestre Botelho, Gabriel Tavares de Almeida Pinto, Searitha Couto Rodrigues, Maria Tereza Miranda Martins, Deivid Lucas Alves Soares, Camille Cardoso Cruz, Aline de Almeida Pinto, Flaviana Rodrigues Fintelman Dias, Patricia Dias Fernandes, Anna Claudia Cunha   +10 more
wiley   +1 more source

Neurohormonok, neuropeptidek szerepe az idegrendszer és az endokrin rendszer adaptatív működésének szabályozásában = The role of neurohormones and neuropeptides in the regulation of the adaptive function of the neural and endocrine system [PDF]

, 2006
Összefoglalás A vizsgált periodusban a vállalt feladat több neuropeptidnek mint a PACAP 38, orexin A és B endomorphin-1, a MERF, apelin-13, urocortin 1 , 2 és 3, valamint a ghrelinnek vizsgálata olyan idegrendszeri funkciókban mint a tanulás és ...
Gecse, Árpád, Hargitainé Bujdosó, Erika, Jászberényi, Miklós, Kiss, Edina, Kálmánné Adamik, Ágnes, Lepránné Mezei, Zsófia, Pataki, Imre, Telegdy, Gyula, Tiricz, Hilda   +8 more
core