Results 71 to 80 of about 23,803 (294)

Synthesis, characterization and biological behavior of some Schiff's and Mannich base derivatives of Lamotrigine

Arabian Journal of Chemistry, 2017
A series of various Schiff's and Mannich base derivatives (N1–2 & ND1–6) of Lamotrigine with isatin and substituted isatin were synthesized to get more potent anticonvulsant agents.
A.A. Kulkarni, S.B. Wankhede, N.D. Dhawale, P.B. Yadav, V.V. Deore, I.D. Gonjari   +5 more
doaj   +1 more source

Integrating Catalysis and Analysis: Accelerated Asymmetric Reaction Development With a Multitasking Reactivity Umpolung/Chiroptical Reporter Auxiliary

Chemistry – A European Journal, EarlyView.
A readily available isatin molecule serves as amine protecting group, reagent for reactivity Umpolung, and as chiroptical yield and enantioselectivity reporter to enable chromatography‐free high‐throughput optimization of an organocatalytic asymmetric Michael addition solely based on the analysis of UV and circular dichroism inductions that are ...
F. Safia Kariapper, Maria Bouda, Christian Wolf   +2 more
wiley   +1 more source

Iodine-catalyzed Synthesis, Antibacterial, and Antioxidant Activity of Isatin Derivatives

Indonesian Journal of Chemistry
Isatin is a unique compound with many bioactivities such as antiviral, anti-HIV, antitumor, anti-inflammatory, anticonvulsant, and antifungal. In this study, isatin derivatives were synthesized with an iodine catalyst and tested for antibacterial and ...
Antonius Herry Cahyana, Agus Rimus Liandi, Yosua Ongkowidjawa   +2 more
doaj   +1 more source

Microwave Synthesis, Characterization, and Antimicrobial Activity of Some Novel Isatin Derivatives

Journal of Chemistry, 2015
Three series of isatin derivatives [3-hydrazino, 3-thiosemicarbazino, and 3-imino carboxylic acid derivatives] were synthesized employing microwave irradiation.
Ayman El-Faham, Wael N. Hozzein, Mohammad A. M. Wadaan, Sherine N. Khattab, Hazem A. Ghabbour, Hoong-Kun Fun, Mohammed Rafiq Siddiqui   +6 more
doaj   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source

A Neuroprotective Dose of Isatin Causes Multilevel Changes Involving the Brain Proteome: Prospects for Further Research

International Journal of Molecular Sciences, 2020
Isatin (indole-2,3-dione) is an endogenous regulator, exhibiting a wide range of biological and pharmacological activities. At doses of 100 mg/kg and above, isatin is neuroprotective in different experimental models of neurodegeneration.
A. Medvedev, A. Kopylov, O. Buneeva, L. Kurbatov, O. Tikhonova, A. Ivanov, V. Zgoda   +6 more
semanticscholar   +1 more source

Facile synthesis of Schiff and Mannich bases of isatin derivatives [PDF]

, 2015
We report herein on the synthesis of some isatin Schiff’s bases (1–11), which were prepared from the reaction of isatin and some aromatic amines. These in turn were converted to the corresponding Mannich bases (12-23) by reaction with a number of ...
Al-azzawi, Nuhad K. E., Al-kadhimi, Ahmed A. H., Khalaf, Abedawn I.   +2 more
core  

The BioColour Library

Coloration Technology, EarlyView.
Abstract The attraction of adopting natural and bio‐based colourants in applications has grown, but their use suffers from a lack of certification bodies, standards and reference data. In the BioColour project, we are developing an open database and tools for the characterisation, authentication and quality analysis of biocolourant sources ...
Joni Hyttinen, Riikka Räisänen, Markku Hauta‐Kasari   +2 more
wiley   +1 more source

A Modified Indigo Method for the Determination of Ozone in Nonaqueous Solvents [PDF]

, 2013
The indigo method for the analysis of aqueous ozone was modified to allow analysis of dissolved ozone in nonaqueous liquid phases. The method was tested using the solvent decamethylcyclopentasiloxane 245 and a vegetable oil. The molar absorptivity at 600
Chedly Tizaoui
core   +1 more source

Indirubin as a red hair Colourant from Indigofera tinctoria L.

International Journal of Cosmetic Science, EarlyView.
An immediate stable red colour result after application of Indigofera tinctoria L. on hair in the presence of isatin and a reducing agent was achieved. A revised indigo molecule and indirubin synthesis pathway for I. tinctoria L. application including the effect of said additives to the colour outcome is presented.
Skrollan Klaas, Volkmar Vill, Fabian Straske   +2 more
wiley   +1 more source