THE SYNTHESIS OF NEW SPIROLACTONES FROM SUBSTITUTED ISATINS [PDF]
Interaction of N-ethyl isatin 3 with dimethyl acetylenedicarboxylate in the presence triphenylphosphine has led to good selectivity of methyl 1'-ethyl-4-methoxy-2',5-dioxo-5H-spiro[furan-2,3'-indoline]-3-carboxylate 4 formation.
Natalia Sucman +5 more
doaj
Background and purpose: Isatin derivatives have excited attention due to their biological attractions, especially, anticancer properties. Isatin analogs such as semaxanib and sunitinib were exposed to tyrosine kinase inhibitory properties.
Farshid Hassanzadeh +4 more
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Room Temperature, Open-Flask C–P Bond-Formation on Water under Catalyst-Free Conditions
A catalyst-free C–P bond-formation in an open flask at room temperature between isatin derivatives and phosphorus surrogates on water is described. Isatin derivatives possessing different substitutes underwent C–P coupling reaction with a variety of ...
Rakhee Choudhary +4 more
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Mitochondria are a crucial target for the actions of neurotoxins, causing symptoms of Parkinson’s disease in various experimental animal models, and also neuroprotectors.
Olga Buneeva +5 more
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Synthesis of 4-Amino-4,5-dihydro-1H-1,2,4-triazole-5-ones and their Isatin-3-imine Derivatives
Iminoester hydrochlorides 1 have been synthesized. These compounds werethen converted into ester ethoxycarbonyl hydrazones 2, from which in turn a new seriesof substituted 4-amino-4,5-dihydro-1H-1,2,4-triazole-5-ones, 3, was then prepared.Finally a set ...
Bahittin Kahveci
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New Inducible Nitric Oxide Synthase and Cyclooxygenase-2 Inhibitors, Nalidixic Acid Linked to Isatin Schiff Bases via Certain l-Amino Acid Bridges [PDF]
Ahmed M. Naglah +5 more
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A case of vaccinia necrosum (or progressive vaccinia), with severe hypogammaglobulinaemia, treated with n-methyl isatin beta-thiosemicarbazone (33T57) [PDF]
T. H. Flewett, F. L. Ker
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Isatin Derivatives as a New Class of Aldose Reductase Inhibitors With Antioxidant Activity [PDF]
Wenchao Liu +7 more
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Synthesis of Schiff and Mannich Bases of Isatin Derivatives with 4-Amino-4,5-Dihydro-1H-1,2,4-Triazole-5-Ones [PDF]
Olcay Bekircan, Hakan Bektaş
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