Results 1 to 10 of about 887,751 (310)
Signal Transduction and Targeted Therapy, 2022 Myocardial ischemia/reperfusion (I/R) injury is a classic type of cardiovascular disease characterized by injury to cardiomyocytes leading to various forms of cell death.
Rong-Rong He
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Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity
Circulation, 2021 Supplemental Digital Content is available in the text. Background: The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) postulated that patients with stable coronary artery disease (CAD) and ...
Harmony R Reynolds +2 more
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Comprehensive Physiology, 2017 ABSTRACTIschemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease, are the most common causes of debilitating disease and death in westernized cultures. The extent of tissue injury relates directly to the extent of blood flow reduction and to the length of the ischemic period, which influence the levels to which ...
Theodore, Kalogeris +3 more
openaire +3 more sources
Cell Death and Differentiation, 2019 Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various diseases such as cancer, Parkinson’s disease, and stroke.
Jihong Yao, X Tian
exaly +2 more sources
Ischemia and reperfusion—from mechanism to translation
Nature Medicine, 2011 Holger K Eltzschig, Tobias Eckle
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International Journal of Molecular Sciences, 2021 Its increasing incidence has led stroke to be the second leading cause of death worldwide. Despite significant advances in recanalization strategies, patients are still at risk for ischemia/reperfusion injuries in this pathophysiology, in which ...
Anamaria Jurcău, A. Simion
semanticscholar +1 more source
Clinical and Applied Thrombosis/Hemostasis, 2022 Previous studies have shown that plaque rupture (PR) is the most important cause of acute coronary syndrome (ACS). However, the potential impact of intra-stent PR on stent failure manifesting as ACS and the optical coherence tomography (OCT) features of ...
Huai Yu MD +5 more
doaj +1 more source
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The EROSION (Effective Anti‐Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography‐Based Management in Plaque Erosion) study demonstrated that antithrombotic therapy without stenting was safe and feasible in selected ...
Yanwei Yin +15 more
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Frontiers in Cardiovascular Medicine, 2022 BackgroundOptical coherence tomography (OCT) is an important modality used in coronary intervention. However, OCT requires a high amount of contrast media, limiting its extensive application in clinical practice.
Tao Chen +29 more
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Cell Death and Disease, 2021 Inducing autophagy and inhibiting apoptosis may provide a therapeutic treatment for atherosclerosis (AS). For the treatment of progressive AS, arsenic trioxide (ATO) has been used to coat vascular stents.
Shaohong Fang +10 more
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