Results 11 to 20 of about 170,400 (293)

AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway

Brain and Behavior, 2021
Background Cerebral ischemia/reperfusion injury is a severe problem in patients with brain ischemia. Brain injury caused by the immune response is important in the pathogenesis of cerebral ischemia/reperfusion injury and immune pathways.
Lichao Fan, Lichun Zhou
doaj   +1 more source

The roles of microRNAs in spinal cord ischemia-reperfusion injury

Neural Regeneration Research, 2022
Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological conditions. However, multiple stimuli can trigger SCII, so the underlying mechanism of this pathology has not
Feng-Shou Chen, Xiang-Yi Tong, Bo Fang, Dan Wang, Xiao-Qian Li, Zai-Li Zhang   +5 more
doaj   +1 more source

Ischemia-Reperfusion Injury in Stroke [PDF]

Interventional Neurology, 2012
Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic stroke continue to debilitate patients with devastating outcomes at both the personal and societal levels. While the ultimate goal of therapy in ischemic stroke is geared towards restoration of blood flow, even when mitigation of initial tissue hypoxia is successful ...
Nour, May, Scalzo, Fabien, Liebeskind, David S   +2 more
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Gender Differential Expression of AR/miR-21 Signaling Axis and Its Protective Effect on Renal Ischemia-Reperfusion Injury

Frontiers in Cell and Developmental Biology, 2022
Objective: The aim of this study was to investigate gender differences after renal ischemia-reperfusion injury in mice and the effects of androgen receptor (AR) and microRNA-21 (miR-21) on apoptosis in renal ischemia-reperfusion injury.Methods: Renal ...
Gaomin Huang, Qiu Yao, Zhenfeng Ye, Yawei Huang, Chiyu Zhang, Yi Jiang, Xiaoqing Xi   +6 more
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Ischemia-Reperfusion Injury and Anesthesia [PDF]

BioMed Research International, 2014
Ischemia-reperfusion injury represents a pathological condition characterized by an initial undersupply of blood to an area or organ followed by a restoration of perfusion and concomitant reoxygenation (= reperfusion). Ischemia typically occurs in the presence of embolism or thrombosis but can also be triggered by surgery and transplantation.
Zarbock, Alexander, Eroglu, Ahmet, Erturk, Engin, Ince, Can, Westphal, Martin   +4 more
openaire   +3 more sources

Post-treatment with JP-1302 protects against renal ischemia/reperfusion-induced acute kidney injury in rats

Journal of Pharmacological Sciences, 2019
Ischemia/reperfusion injury is the most common cause of acute kidney injury. We previously revealed that pre-treatment with yohimbine or JP-1302 attenuated renal ischemia/reperfusion injury by inhibition of α2C-adrenoceptor antagonist.
Takaomi Shimokawa, Hidenobu Tsutsui, Takeshi Miura, Masashi Takama, Kohei Hayashi, Toru Nishinaka, Tomoyuki Terada, Kozo Yoneda, Masayo Yamagata, Tokihito Yukimura   +9 more
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PANoptosis-like cell death in ischemia/reperfusion injury of retinal neurons

Neural Regeneration Research, 2023
PANoptosis is a newly identified type of regulated cell death that consists of pyroptosis, apoptosis, and necroptosis, which simultaneously occur during the pathophysiological process of infectious and inflammatory diseases.
Wei-Tao Yan, Wen-Juan Zhao, Xi-Min Hu, Xiao-Xia Ban, Wen-Ya Ning, Hao Wan, Qi Zhang, Kun Xiong   +7 more
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The Alterations in Mitochondrial Dynamics Following Cerebral Ischemia/Reperfusion Injury

Antioxidants, 2021
Cerebral ischemia results in a poor oxygen supply and cerebral infarction. Reperfusion to the ischemic area is the best therapeutic approach. Although reperfusion after ischemia has beneficial effects, it also causes ischemia/reperfusion (I/R) injury ...
Jirapong Vongsfak, Wasana Pratchayasakul, Nattayaporn Apaijai, Tanat Vaniyapong, Nipon Chattipakorn, Siriporn C. Chattipakorn   +5 more
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Current Mechanistic Concepts in Ischemia and Reperfusion Injury

Cellular Physiology and Biochemistry, 2018
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu, Giou-Teng Yiang, Wan-Ting Liao, Andy Po-Yi Tsai, Yeung-Leung Cheng, Pei-Wen Cheng, Chia-Ying Li, Chia-Jung Li   +7 more
doaj   +1 more source

Complement in Ischemia Reperfusion Injury [PDF]

The American Journal of Pathology, 2003
In the current issue of The American Journal of Pathology Stahl et al describe an important role for the alternative complement pathway in ischemia reperfusion (I/R) of the intestine, using factor D-deficient mice. 1 The requirement for the complement system in I/R-induced tissue injury has been established, but the contribution of the various ...
Niels C, Riedemann, Peter A, Ward
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