Results 31 to 40 of about 1,336,017 (348)

Electroacupuncture Pretreatment Mitigates Myocardial Ischemia/Reperfusion Injury via XBP1/GRP78/Akt Pathway

open access: yesFrontiers in Cardiovascular Medicine, 2021
Myocardial ischemia/reperfusion injury is a common clinical problem and can result in severe cardiac dysfunction. Previous studies have demonstrated the protection of electroacupuncture against myocardial ischemia/reperfusion injury. However, the role of
Nisha Wang   +9 more
doaj   +1 more source

A systematic review of the research progress of non-coding RNA in neuroinflammation and immune regulation in cerebral infarction/ischemia-reperfusion injury

open access: yesFrontiers in Immunology, 2022
Cerebral infarction/ischemia-reperfusion injury is currently the disease with the highest mortality and disability rate of cardiovascular disease. Current studies have shown that nerve cells die of ischemia several hours after ischemic stroke, which ...
Kai-Lin Yang   +8 more
semanticscholar   +1 more source

Ceramide and Ischemia/Reperfusion Injury [PDF]

open access: yesJournal of Lipids, 2018
Ceramide, a bioactive membrane sphingolipid, functions as an important second messenger in apoptosis and cell signaling. In response to stresses, it may be generated by de novo synthesis, sphingomyelin hydrolysis, and/or recycling of complex sphingolipids.
Xingxuan He, Edward H. Schuchman
openaire   +2 more sources

Role of autophagy in hypoxia-reoxygenation-induced injury of rat alveolar epithelial cell type Ⅱ [PDF]

open access: yesJichu yixue yu linchuang, 2021
Objective To investigate the role of autophagy in the hypoxia-reoxygenation (H/R) model of rat alveolar epithelial cell type Ⅱ (AEC Ⅱ). Methods Cells were randomly divided into control group (C),hypoxia-reoxygenation group (H/R),solvent group
LIU Xiu-jie, WANG Xin-yun, SONG Zheng-yang, LOU Guo-qiang, HAO Mao-lin, QIAN Wei, WANG Wan-tie
doaj  

Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia-Reperfusion Injury

open access: yesOxidative Medicine and Cellular Longevity, 2021
Ischemia-reperfusion (I/R) is a pathological process that occurs in many organs and diseases. Reperfusion, recovery of blood flow, and reoxygenation often lead to reperfusion injury. Drug therapy and early reperfusion therapy can reduce tissue injury and
Xin-Ye Li   +11 more
semanticscholar   +1 more source

Ferroptosis: Opportunities and Challenges in Myocardial Ischemia-Reperfusion Injury

open access: yesOxidative Medicine and Cellular Longevity, 2021
Ferroptosis is a newly discovered form of regulated cell death dependent on iron and reactive oxygen species (ROS). It directly or indirectly affects the activity of glutathione peroxidases (GPXs) under the induction of small molecules, causing membrane ...
Wei-Kun Zhao   +3 more
semanticscholar   +1 more source

Ischemia-Reperfusion Injury in Stroke [PDF]

open access: yesInterventional Neurology, 2012
Despite ongoing advances in stroke imaging and treatment, ischemic and hemorrhagic stroke continue to debilitate patients with devastating outcomes at both the personal and societal levels. While the ultimate goal of therapy in ischemic stroke is geared towards restoration of blood flow, even when mitigation of initial tissue hypoxia is successful ...
Nour, May   +2 more
openaire   +4 more sources

Global MicroRNA Expression Profiling of Mouse Livers following Ischemia-Reperfusion Injury at Different Stages. [PDF]

open access: yesPLoS ONE, 2016
Hepatic ischemia-reperfusion injury is a dynamic process consisting of two stages: ischemia and reperfusion, and triggers a cascade of physiological and biochemical events.
Weisheng Zheng   +11 more
doaj   +1 more source

Baicalin Prevents Myocardial Ischemia/Reperfusion Injury Through Inhibiting ACSL4 Mediated Ferroptosis

open access: yesFrontiers in Pharmacology, 2021
Baicalin is a natural flavonoid glycoside that confers protection against myocardial ischemia/reperfusion (I/R) injury. However, its mechanism has not been fully understood.
Zhen-Yu Fan   +4 more
semanticscholar   +1 more source

MicroRNA-670 aggravates cerebral ischemia/reperfusion injury via the Yap pathway

open access: yesNeural Regeneration Research, 2021
Apoptosis is an important programmed cell death process involved in ischemia/reperfusion injury. MicroRNAs are considered to play an important role in the molecular mechanism underlying the regulation of cerebral ischemia and reperfusion injury. However,
Shi-Jia Yu   +4 more
doaj   +1 more source

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