AG490 protects cerebral ischemia/reperfusion injury via inhibiting the JAK2/3 signaling pathway
Background Cerebral ischemia/reperfusion injury is a severe problem in patients with brain ischemia. Brain injury caused by the immune response is important in the pathogenesis of cerebral ischemia/reperfusion injury and immune pathways.
Lichao Fan, Lichun Zhou
doaj +1 more source
Therapeutic interventions of hepatic ischemia-reperfusion injury to attenuate liver dysfunction or multiple organ failure following liver surgery and transplantation remain limited.
Jing Mu +11 more
semanticscholar +1 more source
Application of a novel method for subsequent evaluation of sinusoids and postsinusoidal venules after ischemia-reperfusion injury of rat liver [PDF]
Although several intravital fluorescence microscopic studies demonstrated that microcirculatory derangement is induced during liver ischemia-reperfusion, these data were obtained from randomly selected microvascular areas and microvessels, Repeated ...
Todoroki, T. +5 more
core +1 more source
The roles of microRNAs in spinal cord ischemia-reperfusion injury
Spinal cord ischemia/reperfusion injury is a devastating medical disorder with poor prognosis that is associated with several pathophysiological conditions. However, multiple stimuli can trigger SCII, so the underlying mechanism of this pathology has not
Feng-Shou Chen +5 more
doaj +1 more source
The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans [PDF]
This article is made available through the Brunel Open Access Publishing Fund. It is shared under the Creative Commons License Attribution-Noncommercial No Derivative 3.0 (CCBY NCND).
Carter, SE +10 more
core +1 more source
Macrophage Polarization and Liver Ischemia-Reperfusion Injury
Ischemia-reperfusion injury refers to organ damage caused by the previous insufficient supply of oxygen and nutrients and the involvement of metabolic by-products after blood flow is restored.
Hai Wang +5 more
semanticscholar +1 more source
The uncoordinated-5 homolog B receptor affects hepatic ischemia reperfusion injury [PDF]
Recent evidence has demonstrated additional roles for the neuronal guidance protein receptor UNC5B outside the nervous system. Given the fact that ischemia reperfusion injury (IRI) of the liver is a common source of liver dysfunction and the role of ...
Tiago Granja (147967) +33 more
core +2 more sources
Targeting Oxidative Stress and Inflammation to Prevent Ischemia-Reperfusion Injury
The cerebral ischemia injury can result in neuronal death and/or functional impairment, which leads to further damage and dysfunction after recovery of blood supply.
Li-Quan Wu +6 more
semanticscholar +1 more source
ACE-inhibition prevents postischemic coronary leukocyte adhesion and leukocyte-dependent reperfusion injury [PDF]
Objective: Polymorphonuclear leukocytes (PMN), retained in the microvascular bed, can contribute to postischemic myocardial reperfusion injury. Since a beneficial effect of ACE-inhibition on reperfusion injury has been reported, we investigated the ...
Weber, Christian +7 more
core +1 more source
Tumor Necrosis Factor-α Contributes to Ischemia- and Reperfusion-Induced Endothelial Activation in Isolated Hearts [PDF]
During myocardial reperfusion, polymorphonuclear neutrophil (PMN) adhesion involving the intercellular adhesion molecule-1 (ICAM-1) may lead to aggravation and prolongation of reperfusion injury.
Kelly, Ralph A. +15 more
core +1 more source

