Results 61 to 70 of about 248,009 (208)

Novel roles of κ-opioid receptor in myocardial ischemia-reperfusion injury [PDF]

open access: yesPeerJ
Acute heart attack is the primary cause of cardiovascular-related death worldwide. A common treatment is reperfusion of ischemic tissue, which can cause irreversible damage to the myocardium.
Wen Zhang   +4 more
doaj   +2 more sources

Effect of hydroxyethyl starch on acute renal injury in a model of hepatic ischemia-reperfusion [PDF]

open access: yes, 2012
BACKGROUND: Hepatic vascular control techniques employed during liver surgery are usually associated with ischemia-reperfusion injury, which could cause acute renal dysfunction. The murine model has been used in the study of this injury.
Cabrita, A   +4 more
core  

The role of gut microbiota in myocardial ischemia-reperfusion injury

open access: yesFrontiers in Cardiovascular Medicine
Myocardial ischemia-reperfusion injury denotes the pathological damage resulting from the restoration of blood flow and oxygen supply following acute coronary artery occlusion.
Xin Chen   +9 more
doaj   +1 more source

Anti-inflammatory and antioxidant activity of essential amino acid α-ketoacid analogues against renal ischemia–reperfusion damage in Wistar rats

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2020
Introduction: Essential amino acid α-keto acid analogs are used in the treatment of chronic kidney disease to delay the symptoms of uremia. However, it is unknown whether essential amino acid α-keto acid analogs affect the oxidative stress and the ...
Concepción Sánchez-Martínez   +10 more
doaj   +1 more source

A p38MAPK/MK2 signaling pathway leading to redox stress, cell death and ischemia/reperfusion injury [PDF]

open access: yes, 2014
Background Many diseases and pathological conditions are characterized by transient or constitutive overproduction of reactive oxygen species (ROS).
Ashraf, Muhammad Imtiaz   +17 more
core   +2 more sources

The role of prostaglandin and antioxidant availability in recovery from forearm ischemia-reperfusion injury in humans [PDF]

open access: yes, 2013
This article is made available through the Brunel Open Access Publishing Fund. It is shared under the Creative Commons License Attribution-Noncommercial No Derivative 3.0 (CCBY NCND).
Carter, SE, Faulkner, A, Rakobowchuk, M
core   +1 more source

Ubiquitin-specific protease 7 regulates myocardial ischemia/reperfusion injury by stabilizing Keap1

open access: yesCell Death Discovery, 2022
Myocardial ischemia/reperfusion (I/R) injury is a complex pathological process that is still not fully understood. The oxidative stress response has a critical role in the occurrence and progression of myocardial ischemia/reperfusion injury.
Qiong Xu   +10 more
doaj   +1 more source

Curcumin attenuates myocardial ischemia-reperfusion injury

open access: yesOncotarget, 2017
Cardiovascular diseases (CVDs) are at a badly high-risk of morbidity and mortality in the world.Our study was attempted to investigate the cardioprotective role of curcumin. Hearts injury was assessed in isolated hearts and the rats of coronary artery ligated.The inhibition of pro-inflammatory cytokines was observed by curcumin in coronary artery ...
Liu, Kun   +8 more
openaire   +3 more sources

Combined Cyclosporin A and Hypothermia Treatment Inhibits Activation of BV-2 Microglia but Induces an Inflammatory Response in an Ischemia/Reperfusion Hippocampal Slice Culture Model [PDF]

open access: yes, 2019
Introduction: Hypothermia attenuates cerebral ischemia-induced neuronal cell death associated with neuroinflammation. The calcineurin inhibitor cyclosporin A (CsA) has been shown to be neuroprotective by minimizing activation of inflammatory pathways.
Berger, Felix   +5 more
core   +1 more source

Thiopental improves renal ischemia–reperfusion injury

open access: yesRenal Failure, 2010
Ischemia/reperfusion (I/R) occurs in a number of pathological conditions, including myocardial infarction, stroke, aortic surgery, cardiopulmonary bypass surgery, organ transplantation, resuscitation, and critical care. Massive and abrupt release of oxygen-free radicals after reperfusion triggers oxidative damage.
Dogan, Zafer   +7 more
openaire   +3 more sources

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