Results 41 to 50 of about 248,009 (208)

Gut microbiota-derived gamma-aminobutyric acid from metformin treatment reduces hepatic ischemia/reperfusion injury through inhibiting ferroptosis

eLife
Hepatic ischemia/reperfusion injury (HIRI) is a common and inevitable factor leading to poor prognosis in various liver diseases, making the outcomes of current treatments in clinic unsatisfactory.
Fangyan Wang, Xiujie Liu, Furong Huang, Yan Zhou, Xinyu Wang, Zhengyang Song, Sisi Wang, Xiaoting Wang, Dibang Shi, Gaoyi Ruan, Xiawei Ji, Eryao Zhang, Zenglin Tan, Yuqing Ye, Chuang Wang, Jesse Zhu, Wantie Wang   +16 more
doaj   +1 more source

The heartbreak of depression: 'Psycho-cardiac' coupling in myocardial infarction [PDF]

, 2017
Ample evidence identifies strong links between major depressive disorder (MDD) and both risk of ischemic or coronary heart disease (CHD) and resultant morbidity and mortality. The molecular mechanistic bases of these linkages are poorly defined. Systemic
Budiono, Boris P, Headrick, John P., Neumann, David L., Peart, Jason N., Shum, David H K, Stapelberg, Nicolas J C   +5 more
core   +1 more source

Myocardial ischemia – reperfusion injury

Zaporozhye Medical Journal, 2023
Aim. To summarize and broaden the idea about mechanisms of acute coronary insufficiency development and pathophysiological features of myocardial reperfusion injury. Today, in the event of acute coronary syndrome, according to the latest recommendations for myocardial revascularization, percutaneous coronary intervention should be performed to ...
S. V. Salo, V. O. Shumakov, S. S. Shpak, V. V. Tokhtarov   +3 more
openaire   +4 more sources

Dexamethasone Ameliorates Renal Ischemia-Reperfusion Injury [PDF]

Journal of the American Society of Nephrology, 2009
In the setting of renal ischemia-reperfusion injury (IRI), the effect and mechanism of action of glucocorticoids are not well understood. In rat renal IRI, a single dose of dexamethasone administered before ischemia, or at the onset of reperfusion, ameliorated biochemical and histologic acute kidney injury after 24 h.
Kumar S, Allen DA, Kieswich JE, Patel NS, Harwood S, Mazzon E, CUZZOCREA, Salvatore, Raftery MJ, Thiemermann C, Yaqoob M.M.   +9 more
openaire   +2 more sources

The Safety and Efficacy of Intravascular Lithotripsy in the Treatment of Severe Coronary Artery Calcification in 261 Cases: A Retrospective Study

Health Science Reports
Background Coronary artery calcification is strongly linked to factors such as advanced age, dyslipidemia, and chronic kidney disease. Severe coronary artery calcification significantly elevates the complexity and risk of percutaneous coronary ...
Tiankun Wu, Honghui Yang, Guian Xu, Qingman Li, Lijie Zhu, Yapan Yang, Tingjie Yang   +6 more
doaj   +1 more source

Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention

Neural Regeneration Research
Calcium influx into neurons triggers neuronal death during cerebral ischemia/reperfusion injury. Various calcium channels are involved in cerebral ischemia/reperfusion injury. Cav3.2 channel is a main subtype of T-type calcium channels.
Feibiao Dai, Chengyun Hu, Xue Li, Zhetao Zhang, Hongtao Wang, Wanjun Zhou, Jiawu Wang, Qingtian Geng, Yongfei Dong, Chaoliang Tang   +9 more
doaj   +1 more source

The meaning of different forms of structural myocardial injury, immune response and timing of infarct necrosis and cardiac repair [PDF]

, 2015
Although a decline in the all-cause and cardiac mortality rates following myocardial infarction (MI) during the past 3 decades has been reported, MI is a major cause of death and disability worldwide.
Bello, S, Fineschi, Vittorio, Neri, M, Pomara, C, Riezzo, I, Turillazzi, E   +5 more
core   +1 more source

Aldehyde dehydrogenase 2 overexpression inhibits neuronal apoptosis after spinal cord ischemia/reperfusion injury

Neural Regeneration Research, 2017
Aldehyde dehydrogenase 2 (ALDH2) is an important factor in inhibiting oxidative stress and has been shown to protect against renal ischemia/reperfusion injury.
Xing-zhen Liu, Xin Sun, Kang-ping Shen, Wen-jie Jin, Zhi-yi Fu, Hai-rong Tao, Zhi-xing Xu   +6 more
doaj   +1 more source

Propofol has delayed myocardial protective effects after a regional ischemia/reperfusion injury in an in vivo rat heart model [PDF]

Korean Journal of Anesthesiology, 2010
BackgroundIt is well known that propofol protects myocardium against myocardial ischemia/reperfusion injury in the rat heart model. The aim of this study was to investigate whether propofol provides a protective effect against a regional myocardial ...
Il Woo Shin, In Seok Jang, Seung-Hwa Lee, Ji-Seok Baik, Kyeong-Eon Park, Ju-Tae Sohn, Heon Keun Lee, Young Kyun Chung   +7 more
doaj   +1 more source

The effects of Bilirubin and Bilirubin-di-taurate on ischemia reperfusion injruy in a rat model of kidney transplantation [PDF]

, 2011
Background: Heme oxygenase-1 (HO-1) is the rate-limiting enzyme in the conversion of heme into biliverdin, carbon monoxide (CO) and free iron. Biliverdin is then subsequently reduced to bilirubin by the enzyme bilverdin reductase.
Thomas, Michael
core