Role of Mitochondrial Pathways in Cell Apoptosis during He-Patic Ischemia/Reperfusion Injury
International Journal of Molecular Sciences, 2022 Hepatic ischemia-reperfusion injury is a major cause of post-operative hepatic dysfunction and liver failure after transplantation. Mitochondrial pathways can be either beneficial or detrimental to hepatic cell apoptosis during hepatic ischemia ...
Sen Zhang +5 more
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Glutathione treatment protects the rat liver against injury after warm ischemia and Kupffer cell activation [PDF]
, 2002 Background/Aim: The generation of reactive oxygen species by activated Kupffer cells (KC) may contribute to reperfusion injury of the liver during liver transplantation or resection.
Schauer, R. +11 more
core +1 more source
Myocardial Ischemia-Reperfusion Injury: Therapeutics from a Mitochondria-Centric Perspective
The Cardiology, 2021 Coronary arterial disease is the most common cardiovascular disease. Myocardial ischemia-reperfusion injury caused by the initial interruption of organ blood flow and subsequent restoration of organ blood flow is an important clinical problem with ...
Manli Zhou +7 more
semanticscholar +1 more source
Phosphorylation of Vasodilator-Stimulated Phosphoprotein (VASP) dampens hepatic ischemia-reperfusion injury [PDF]
, 2011 Recent work has demonstrated that the formation of platelet neutrophil complexes (PNCs) affects inflammatory tissue injury. Vasodilator-stimulated phosphoprotein (VASP) is crucially involved into the control of PNC formation and myocardial reperfusion ...
Birk, Philipp +13 more
core +2 more sources
A novel laser-doppler flowmetry assisted murine model of acute hindlimb ischemia-reperfusion for free flap research [PDF]
, 2013 Suitable and reproducible experimental models of translational research in reconstructive surgery that allow in-vivo investigation of diverse molecular and cellular mechanisms are still limited.
Isabella Kanzler +30 more
core +1 more source
Cyclosporine A attenuates apoptosis and necrosis after ischemia-reperfusion-induced renal injury in transiently hyperglycemic rats [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To investigate the effects of cyclosporine A on renal ischemia-reperfusion injury during transient hyperglycemia in rats. Methods: In a model of ischemia-reperfusion-induced renal injury and transiently induced hyperglycemia by intraperitoneal
Sylvio Valença de Lemos Neto +9 more
doaj +1 more source
Anti-cerebral ischemia reperfusion injury of polysaccharides: A review of the mechanisms.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021 Cerebral ischemia-reperfusion injury can lead to a series of serious brain diseases and cause death or different degrees of disability. Polysaccharide is a kind of biological macromolecule with multiple pharmacological activities and has been proven that
Qiang-Hua Yuan +6 more
semanticscholar +1 more source
Role of NO in Ischemia/Reperfusion Injury
Renal Failure, 2013 Dear Editor,In the current issue of Renal Failure, Ilhan et al. reported that hyperbaric oxygen (HBO) therapy induced renoprotection in a rodent model of renal ischemia/reperfusion (IR) injury.1 Th...
Musa, Salmanoglu, Yalçın, Onem
openaire +2 more sources
Natural Product Communications, 2015 The effect of puerarin (Pur) on expressions of Fas/FasL mRNAs in pulmonary ischemia and reperfusion injury (PIRI) in rabbit was investigated. The sole side lung ischemia and reperfusion model was used.
Mengxiao Zheng +5 more
doaj +1 more source
Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury
Frontiers in Aging Neuroscience, 2021 Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window ...
Luoan Shen +7 more
semanticscholar +1 more source