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Circulation, 2023 Background: Myocardial ischemia-reperfusion (I/R) injury causes cardiac dysfunction to myocardial cell loss and fibrosis. Prevention of cell death is important to protect cardiac function after I/R injury.
Wenbin Cai +9 more
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Lymphocytes and ischemia-reperfusion injury [PDF]
Transplantation Reviews, 2009 Ischemia reperfusion injury (IRI) is a common and important clinical problem in many different organ systems, including kidney, brain, heart, liver, lung, and intestine. IRI occurs during all deceased donor organ transplants. IRI is a highly complex cascade of events that includes interactions between vascular endothelium, interstitial compartments ...
Douglas, Linfert +2 more
openaire +2 more sources
Abnormalities of glucose and lipid metabolism in myocardial ischemia-reperfusion injury.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023 Myocardial ischemia-reperfusion injury is a common condition in cardiovascular diseases, and the mechanism of its occurrence involves multiple complex metabolic pathways and signaling pathways.
Hao Tian +3 more
semanticscholar +1 more source
'Myocardial Ischemia-Reperfusion Injury and the Influence of Inflammation.
Trends in cardiovascular medicine, 2022 Acute myocardial infarction is caused by a sudden coronary artery occlusion and leads to ischemia in the corresponding myocardial territory which generally results in myocardial necrosis.
M. Algoet +6 more
semanticscholar +1 more source
Ischemia-Reperfusion Injury and Anesthesia [PDF]
BioMed Research International, 2014 Ischemia-reperfusion injury represents a pathological condition characterized by an initial undersupply of blood to an area or organ followed by a restoration of perfusion and concomitant reoxygenation (= reperfusion). Ischemia typically occurs in the presence of embolism or thrombosis but can also be triggered by surgery and transplantation.
Zarbock, Alexander +4 more
openaire +3 more sources
Experimental and Therapeutic Medicine, 2022 Myocardial infarction is one of the primary causes of mortality in patients with coronary heart disease worldwide. Early treatment of acute myocardial infarction restores blood supply of ischemic myocardium and decreases the mortality risk. However, when
Jianfeng He +6 more
semanticscholar +1 more source
Complement in Ischemia Reperfusion Injury [PDF]
The American Journal of Pathology, 2003 In the current issue of The American Journal of Pathology Stahl et al describe an important role for the alternative complement pathway in ischemia reperfusion (I/R) of the intestine, using factor D-deficient mice. 1 The requirement for the complement system in I/R-induced tissue injury has been established, but the contribution of the various ...
Niels C, Riedemann, Peter A, Ward
openaire +2 more sources
Q50, an Iron-Chelating and Zinc-Complexing Agent, Improves Cardiac Function in Rat Models of Ischemia/Reperfusion-Induced Myocardial Injury [PDF]
, 2013 Background: Reperfusion of ischemic myocardium may contribute to substantial cardiac tissue damage, but the addition of iron chelators, zinc or zinc complexes has been shown to prevent heart from reperfusion injury.
Faragó, Nóra +43 more
core +2 more sources
Renoprotective effects of dexmedetomidine against ischemia-reperfusion injury in streptozotocin-induced diabetic rats. [PDF]
PLoS ONE, 2018 BACKGROUND:Diabetic patients are susceptible to renal ischemia-reperfusion injury, which leads to perioperative complications. Activation of NOD-like receptor protein 3 (NLRP3) inflammasome participates in the development of diabetes, and contributes to ...
Seung Hyun Kim +5 more
doaj +1 more source
Frontiers in Immunology, 2022 Liver transplantation is the ultimate method for treating end-stage liver disease. With the increasing prevalence of obesity, the number of patients with non-alcoholic fatty liver, a common cause of chronic liver disease, is on the rise and may become ...
S. Tang +5 more
semanticscholar +1 more source