Results 11 to 20 of about 968,316 (339)
Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury [PDF]
Frontiers in Aging Neuroscience, 2021 Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window has been extended to over 24 h.
Chengmei Sun +8 more
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Journal of Education and Teaching in Emergency Medicine, 2016 Audience: This simulation session is appropriate for emergency medicine residents at any level or medical students. Introduction: Mesenteric ischemia is a rare, but serious cause of abdominal pain. Practitioners must recognize the diagnosis quickly. The clinical course rapidly advances from bowel ischemia to infarction, sepsis, and frequently death ...
Daniel G, Clair, Jocelyn M, Beach
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Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury [PDF]
Circulation Research, 2022 Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for translation to the clinic is understanding the mechanism of malonate entry into cells to enable inhibition of SDH, its mitochondrial target, as malonate ...
Prag, Hiran A +14 more
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Indian Heart Journal, 2020 The International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (ISCHEMIA) study was published recently demonstrating that over a period of 3.3 years a routine invasive approach along with optimised medical therapy (OMT) was not superior to OMT alone in patients with stable coronary artery disease and at least moderate ...
Thomas, Boban, Hassan, Imad
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Effect of ischemia on the canine large bowel: A comparison with the small intestine [PDF]
, 1996 Mucosal injury caused by ischemia and reperfusion has been well documented with the small intestine, but little is known about the colon. In the present study, the effect of warm and cold ischemia on the canine colon was studied and compared to that on ...
Ikoma, A +6 more
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Lipids in Health and Disease, 2017 Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen +5 more
doaj +1 more source
Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]
, 1990 A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L +3 more
core +1 more source
Frontiers in Pharmacology, 2021 Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang +22 more
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Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro
Stem Cell Research & Therapy, 2017 Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin +6 more
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BMC Cardiovascular Disorders, 2022 Background Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndrome treated with primary ...
Abigail Demuyakor +17 more
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