Results 11 to 20 of about 1,309,370 (384)
Journal of Education and Teaching in Emergency Medicine, 2016 Mesenteric ischemia is caused by blood flow that is insufficient to meet the metabolic demands of the visceral organs. The severity of ischemia and the type of organ involved depend on the affected vessel and the extent of collateral-vessel blood flow ...
Daniel G. Clair, Jocelyn M. Beach
semanticscholar +9 more sources
Failed ISCHEMIA Trial or Failed Ischemia Testing? [PDF]
Journal of Invasive Cardiology, 2020 The results of the ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approach) trial were presented at the American Heart Association Scientific Sessions in November, 2019 in Philadelphia, Pennsylvania, and ...
Budoff, Matthew J, Dahal, Suraj
core +4 more sources
Comprehensive Physiology, 2017 Ischemic disorders, such as myocardial infarction, stroke, and peripheral vascular disease, are the most common causes of debilitating disease and death in westernized cultures.
Theodore Kalogeris +3 more
semanticscholar +3 more sources
International Journal of Molecular Sciences, 2021 Its increasing incidence has led stroke to be the second leading cause of death worldwide. Despite significant advances in recanalization strategies, patients are still at risk for ischemia/reperfusion injuries in this pathophysiology, in which ...
Anamaria Jurcău, A. Simion
semanticscholar +1 more source
Mitophagy in Cerebral Ischemia and Ischemia/Reperfusion Injury [PDF]
Frontiers in Aging Neuroscience, 2021 Ischemic stroke is a severe cerebrovascular disease with high mortality and morbidity. In recent years, reperfusion treatments based on thrombolytic and thrombectomy are major managements for ischemic stroke patients, and the recanalization time window has been extended to over 24 h.
Chengmei Sun +8 more
openaire +4 more sources
Clinical and Applied Thrombosis/Hemostasis, 2022 Previous studies have shown that plaque rupture (PR) is the most important cause of acute coronary syndrome (ACS). However, the potential impact of intra-stent PR on stent failure manifesting as ACS and the optical coherence tomography (OCT) features of ...
Huai Yu MD +5 more
doaj +1 more source
Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury [PDF]
Circulation Research, 2022 Background: Inhibiting SDH (succinate dehydrogenase), with the competitive inhibitor malonate, has shown promise in ameliorating ischemia/reperfusion injury. However, key for translation to the clinic is understanding the mechanism of malonate entry into cells to enable inhibition of SDH, its mitochondrial target, as malonate ...
Prag, Hiran A +14 more
openaire +7 more sources
Effect of Ischemia on Known Substrates and Cofactors of the Glycolytic Pathway in Brain
Journal of Biological Chemistry, 1964 Oliver H. Lowry +3 more
openalex +2 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The EROSION (Effective Anti‐Thrombotic Therapy Without Stenting: Intravascular Optical Coherence Tomography‐Based Management in Plaque Erosion) study demonstrated that antithrombotic therapy without stenting was safe and feasible in selected ...
Yanwei Yin +15 more
doaj +1 more source
Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity
Circulation, 2021 Supplemental Digital Content is available in the text. Background: The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) postulated that patients with stable coronary artery disease (CAD) and ...
H. Reynolds +22 more
semanticscholar +1 more source