Results 11 to 20 of about 1,043,947 (356)

Lipid peroxidation is a nonparenchymal cell event with reperfusion after prolonged liver ischemia [PDF]

open access: yes, 1990
A proposed mechanism for irreversible ischemic liver damage has been peroxidation of membrane phospholipids by free radicals. However, the hepatocyte is laden with enzymes which are antioxidants and, therefore, ought to be relatively resistant to ...
Makowka, L   +3 more
core   +1 more source

A novel swine model for evaluation of dyslipidemia and atherosclerosis induced by human CETP overexpression

open access: yesLipids in Health and Disease, 2017
Background The mechanism of cholesteryl ester transfer protein (CETP) in lipid metabolism is still unclear. Furthermore, the relationship of CETP and atherosclerosis (AS) has been controversial. As pigs are a good model for both lipid and AS research, we
Tao Chen   +5 more
doaj   +1 more source

Lactate concentration gradient from right atrium to pulmonary artery: a commentary [PDF]

open access: yes, 2005
Inadequate myocardial performance is a common complication of severe sepsis. Studies in humans strongly argue against a decrease in coronary blood flow in the pathogenesis of this sepsis-induced cardiac injury.
Creteur, Jacques
core   +2 more sources

Omentin-1 effects on mesenchymal stem cells: proliferation, apoptosis, and angiogenesis in vitro

open access: yesStem Cell Research & Therapy, 2017
Background Mesenchymal stem cells (MSCs) are emerging as an extremely promising therapeutic agent for tissue repair. However, limitations exist such as the low numbers of MSCs obtained from donors, and the poor survival and function of donor cells ...
Li Yin   +6 more
doaj   +1 more source

C1q/TNF-Related Protein 9 Attenuates Atherosclerosis by Inhibiting Hyperglycemia-Induced Endothelial Cell Senescence Through the AMPKα/KLF4 Signaling Pathway

open access: yesFrontiers in Pharmacology, 2021
Hyperglycemia-induced endothelial cell senescence has been widely reported to be involved in the pathogenesis of type 2 diabetes mellitus‒accelerated atherosclerosis.
Gang Wang   +22 more
doaj   +1 more source

Purine nucleoside phosphorylase: A new marker for free oxygen radical injury to the endothelial cell [PDF]

open access: yes, 1990
The effect of ischemia and reperfusion on purine nucleoside phosphorylase was studied in an isolated perfused rat liver model. This enzyme is localized primarily in the cytoplasm of the endothelial and Kupffer cells; some activity is associated with the ...
Abouna   +32 more
core   +1 more source

Achieved low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio predicts the pathophysiological evolution of lipid-rich plaques in acute coronary syndromes: an optical coherence tomography study

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundAs a novel lipoprotein ratio, baseline low-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (LHR) is closely related to the clinical outcomes of acute coronary syndromes (ACS) after percutaneous coronary ...
Luping He   +21 more
doaj   +1 more source

Transient limb ischemia induces remote ischemic preconditioning in vivo [PDF]

open access: yes, 2002
Background-Ischemic preconditioning reduces local tissue injury caused by subsequent ischemia-reperfusion (IR), but may also have a salutary effect on IR injury of tissues remote from those undergoing preconditioning.
Hoschtitzky, JA   +9 more
core   +1 more source

Impact of nodular calcification in patients with acute coronary syndrome (ACS) treated with primary percutaneous coronary intervention (PCI)

open access: yesBMC Cardiovascular Disorders, 2022
Background Calcified plaque is thought to adversely impact outcomes after percutaneous coronary intervention (PCI). This study sought to evaluate the impact of nodular calcification in patients with acute coronary syndrome treated with primary ...
Abigail Demuyakor   +17 more
doaj   +1 more source

Relationship between non-culprit lesion plaque characteristics changes and in-stent neoatherosclerosis formation: 1-year follow-up optical coherence tomography study

open access: yesReviews in Cardiovascular Medicine, 2021
The relationship between the in-stent neoatherosclerosis (ISNA) formation and the plaque’s characteristic changes in the non-culprit lesion is unclear.
Lei Xing   +10 more
doaj   +1 more source

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