Results 41 to 50 of about 1,309,370 (384)

Focal Geometry and Characteristics of Erosion-Prone Coronary Plaques in vivo Angiography and Optical Coherence Tomography Study

open access: yesFrontiers in Cardiovascular Medicine, 2021
Objective: This study compared focal geometry and characteristics of culprit plaque erosion (PE) vs. non-culprit plaques in ST-segment elevated myocardial infarction (STEMI) patients in whom optical coherence tomography (OCT) identified PE as the cause ...
Muhua Cao   +20 more
doaj   +1 more source

Neuroprotective efficacy of nimesulide against hippocampal neuronal damage following transient forebrain ischemia [PDF]

open access: yes, 2002
Cyclooxygenase-2 is involved in the inflammatory component of the ischemic cascade, playing an important role in the delayed progression of the brain damage.
Alvarez, Dalia   +7 more
core   +1 more source

NOX1 promotes myocardial fibrosis and cardiac dysfunction via activating the TLR2/NF-κB pathway in diabetic cardiomyopathy

open access: yesFrontiers in Pharmacology, 2022
Diabetic cardiomyopathy (DCM) is a prevalent complication in patients with diabetes, resulting in high morbidity and mortality. However, the molecular mechanisms of diabetic cardiomyopathy have yet to be fully elucidated. In this study, we investigated a
Dandan Zhang   +15 more
doaj   +1 more source

Lactate concentration gradient from right atrium to pulmonary artery: a commentary [PDF]

open access: yes, 2005
Inadequate myocardial performance is a common complication of severe sepsis. Studies in humans strongly argue against a decrease in coronary blood flow in the pathogenesis of this sepsis-induced cardiac injury.
Creteur, Jacques
core   +2 more sources

Predicting Diagnostic Gene Biomarkers Associated With Immune Checkpoints, N6-Methyladenosine, and Ferroptosis in Patients With Acute Myocardial Infarction

open access: yesFrontiers in Cardiovascular Medicine, 2022
This study aimed to determine early diagnosis genes of acute myocardial infarction (AMI) and then validate their association with ferroptosis, immune checkpoints, and N6-methyladenosine (m6A), which may provide a potential method for the early diagnosis ...
Xiao Tong   +9 more
doaj   +1 more source

Current Mechanistic Concepts in Ischemia and Reperfusion Injury

open access: yesCellular Physiology and Biochemistry, 2018
Ischemia-reperfusion injury is associated with serious clinical manifestations, including myocardial hibernation, acute heart failure, cerebral dysfunction, gastrointestinal dysfunction, systemic inflammatory response syndrome, and multiple organ ...
Meng-Yu Wu   +7 more
semanticscholar   +1 more source

Neonatal hypoxia-ischemia in rat elicits a region-specific neurotrophic response in SVZ microglia

open access: yesJournal of Neuroinflammation, 2020
Background Recent findings describe microglia as modulators of neurogenesis in the subventricular zone (SVZ). SVZ microglia in the adult rat are thought to adopt a neurotrophic phenotype after ischemic stroke.
Urs Fisch   +4 more
doaj   +1 more source

Artificial Intelligence—A Good Assistant to Multi-Modality Imaging in Managing Acute Coronary Syndrome

open access: yesFrontiers in Cardiovascular Medicine, 2022
Acute coronary syndrome is the leading cause of cardiac death and has a significant impact on patient prognosis. Early identification and proper management are key to ensuring better outcomes and have improved significantly with the development of ...
Ming-hao Liu   +9 more
doaj   +1 more source

Effect of ischemia on the canine large bowel: A comparison with the small intestine [PDF]

open access: yes, 1996
Mucosal injury caused by ischemia and reperfusion has been well documented with the small intestine, but little is known about the colon. In the present study, the effect of warm and cold ischemia on the canine colon was studied and compared to that on ...
Ikoma, A   +6 more
core   +1 more source

Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion

open access: yesCell Death and Differentiation, 2019
Ferroptosis is a recently identified form of regulated cell death defined by the iron-dependent accumulation of lipid reactive oxygen species. Ferroptosis has been studied in various diseases such as cancer, Parkinson’s disease, and stroke.
Yang Li   +10 more
semanticscholar   +1 more source

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