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Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke [PDF]

open access: yesNeural Regeneration Research, 2022
During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma   +14 more
doaj   +2 more sources

Effects of Ischemic Postconditioning and Long Non-Coding RNAs in Ischemic Stroke [PDF]

open access: yesBioengineered, 2022
Stroke is a main cause of disability and death among adults in China, and acute ischemic stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the blocked blood vessels. However, more than 90% of patients cannot receive effective treatment within an appropriate time, and delayed recanalization of blood vessels causes ...
Liyan Li, Jianhui Guo
exaly   +4 more sources

Protective Effect of Ischemic Postconditioning Against Ischemia Reperfusion-Induced Myocardium Oxidative Injury in IR Rats

open access: yesMolecules, 2012
Brief episodes of myocardial ischemia-reperfusion (IR) employed during reperfusion after a prolonged ischemic insult may attenuate the total ischemia-reperfusion injury. This phenomenon has been termed ischemic postconditioning.
Jiangwei Ma, Li Zhang, Huajin Liu
exaly   +3 more sources

Neuroprotective effect of ischemic postconditioning against hyperperfusion and its mechanisms of neuroprotection [PDF]

open access: yesJournal of Research in Medical Sciences
Background: In recent years, stroke and ischemia–reperfusion injury has motivated researchers to find new ways to reduce the complications. Although reperfusion is essential for brain survival, it is like a double-edged sword that may cause further ...
Seyyed Majid Bagheri   +2 more
doaj   +2 more sources

Ischemic pre and postconditioning in skeletal muscle injury produced by ischemia and reperfusion in rats [PDF]

open access: yesActa Cirúrgica Brasileira, 2013
PURPOSE: To investigate the protective effects of ischemic pre and postconditioning, as well as the association of both methods, in skeletal muscle injury produced by ischemia and reperfusion in rats.
José Alves Lintz   +3 more
doaj   +3 more sources

Protection of ischemic postconditioning against neuronal apoptosis induced by transient focal ischemia is associated with attenuation of NF-κB/p65 activation. [PDF]

open access: yesPLoS ONE, 2014
Background and purposeAccumulating evidences have demonstrated that nuclear factor κB/p65 plays a protective role in the protection of ischemic preconditioning and detrimental role in lethal ischemia-induced programmed cell death including apoptosis and ...
Jianmin Liang   +5 more
doaj   +1 more source

Ischemic postconditioning decreases cerebral edema and brain blood barrier disruption caused by relief of carotid stenosis in a rat model of cerebral hypoperfusion. [PDF]

open access: yesPLoS ONE, 2013
BACKGROUND AND PURPOSE: Complications due to brain edema and breakdown of blood brain barrier are an important factor affecting the treatment effects of patients with severe carotid stenosis.
Fuwei Yang   +6 more
doaj   +1 more source

Ischemic postconditioning may not influence early brain injury induced by focal cerebral ischemia/reperfusion in rats [PDF]

open access: yesKorean Journal of Anesthesiology, 2010
BackgroundExperimental studies have shown that ischemic postconditioning can reduce neuronal injury in the setting of cerebral ischemia, but the mechanisms are not yet clearly elucidated.
Yoo Kyung Kim   +3 more
doaj   +1 more source

Delayed postconditioning protects against focal ischemic brain injury in rats. [PDF]

open access: yesPLoS ONE, 2008
We and others have reported that rapid ischemic postconditioning, interrupting early reperfusion after stroke, reduces infarction in rats. However, its extremely short therapeutic time windows, from a few seconds to minutes after reperfusion, may hinder ...
Chuancheng Ren   +5 more
doaj   +1 more source

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