Neuroprotective effects of long noncoding RNAs involved in ischemic postconditioning after ischemic stroke [PDF]
Neural Regeneration Research, 2022 During acute reperfusion, the expression profiles of long noncoding RNAs in adult rats with focal cerebral ischemia undergo broad changes. However, whether long noncoding RNAs are involved in neuroprotective effects following focal ischemic stroke in ...
Wei Ma +14 more
doaj +2 more sources
Cerebral in situ ischemic postconditioning: From bench to bedside and beyond. [PDF]
NeuroprotectionThis review explores the translational potential of in situ ischemic postconditioning in acute ischemic stroke. Preclinical and clinical evidence is summarized to highlight its promise as a neuroprotective strategy in the era of endovascular therapy.
Jiang X, Zhao W, Xu Y, Meng F, Wei M.
europepmc +2 more sources
Neuroprotective effect of ischemic postconditioning against hyperperfusion and its mechanisms of neuroprotection [PDF]
Journal of Research in Medical SciencesBackground: In recent years, stroke and ischemia–reperfusion injury has motivated researchers to find new ways to reduce the complications. Although reperfusion is essential for brain survival, it is like a double-edged sword that may cause further ...
Seyyed Majid Bagheri +2 more
doaj +2 more sources
Effects of ischemic postconditioning and long non-coding RNAs in ischemic stroke [PDF]
Bioengineered, 2022 Stroke is a main cause of disability and death among adults in China, and acute ischemic stroke accounts for 80% of cases. The key to ischemic stroke treatment is to recanalize the blocked blood vessels. However, more than 90% of patients cannot receive effective treatment within an appropriate time, and delayed recanalization of blood vessels causes ...
Wei Ma +10 more
openaire +3 more sources
IONIC HOMEOSTASIS IN BRAIN CONDITIONING [PDF]
Frontiers in Neuroscience, 2015 Most of the research aimed at identifying new stroke therapies focuses on strategies which induce, mimic, or boost endogenous protective responses. Preconditioning is a protective strategy in which a subliminal stimulus is applied before a subsequent ...
Ornella eCuomo +9 more
doaj +3 more sources
Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]
, 2009 Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Meybohm, Patrick +9 more
core +17 more sources
Protection of ischemic postconditioning against neuronal apoptosis induced by transient focal ischemia is associated with attenuation of NF-κB/p65 activation. [PDF]
PLoS ONE, 2014 Background and purposeAccumulating evidences have demonstrated that nuclear factor κB/p65 plays a protective role in the protection of ischemic preconditioning and detrimental role in lethal ischemia-induced programmed cell death including apoptosis and ...
Jianmin Liang +5 more
doaj +1 more source
Ischemic pre and postconditioning in skeletal muscle injury produced by ischemia and reperfusion in rats [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To investigate the protective effects of ischemic pre and postconditioning, as well as the association of both methods, in skeletal muscle injury produced by ischemia and reperfusion in rats.
José Alves Lintz +3 more
doaj +3 more sources
Ischemic postconditioning decreases cerebral edema and brain blood barrier disruption caused by relief of carotid stenosis in a rat model of cerebral hypoperfusion. [PDF]
PLoS ONE, 2013 BACKGROUND AND PURPOSE: Complications due to brain edema and breakdown of blood brain barrier are an important factor affecting the treatment effects of patients with severe carotid stenosis.
Fuwei Yang +6 more
doaj +1 more source
Ischemic postconditioning may not influence early brain injury induced by focal cerebral ischemia/reperfusion in rats [PDF]
Korean Journal of Anesthesiology, 2010 BackgroundExperimental studies have shown that ischemic postconditioning can reduce neuronal injury in the setting of cerebral ischemia, but the mechanisms are not yet clearly elucidated.
Yoo Kyung Kim +3 more
doaj +1 more source