Ischemic postconditioning: a clinical perspective
Interventional Cardiology, 2010 Primary percutaneous coronary intervention is the recommended therapy for patients with ST‑elevation myocardial infarction. However, restoration of coronary blood flow may lead to reperfusion injury, which has been suggested to account for 50% of the final myocardial infarct size.
Lønborg, Jacob +2 more
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Protective effect of renal ischemic postconditioning in renal ischemic-reperfusion injury [PDF]
Translational Andrology and Urology, 2020 Renal ischemic postconditioning (RIPo) can protect the kidney from renal ischemia/reperfusion injury (RIRI). However, the underlying molecular mechanisms for RIPo in renal protection remained elusive. This study aimed to investigate the renoprotective effects of RIPo in an RIR rat model.The Sprague Dawley (SD) rats were randomly divided into three ...
Tian, Ying +4 more
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The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]
, 2012 This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L +5 more
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Is there a role for ischaemic conditioning in cardiac surgery? [PDF]
, 2017 Coronary artery disease (CAD) is a major cause of morbidity and mortality worldwide. Coronary artery bypass graft (CABG) surgery is the revascularisation strategy of choice in patients with diabetes mellitus and complex CAD. Owing to a number of factors,
Candilio, L, Hausenloy, D
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Neurobiology of Disease, 2013 It has recently been hypothesized that a sub-lethal ischemic insult induced in one organ is able to protect from a harmful ischemia occurring in a different organ.
Giuseppe Pignataro +6 more
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Intravenous sodium nitrite in acute ST-elevation myocardial infarction: a randomized controlled trial (NIAMI). [PDF]
, 2014 AIM: Despite prompt revascularization of acute myocardial infarction (AMI), substantial myocardial injury may occur, in part a consequence of ischaemia reperfusion injury (IRI). There has been considerable interest in therapies that may reduce IRI.
A. de Belder +73 more
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Comparison of remote and local postconditioning against hepatic ischemic-reperfusion injury in rats [PDF]
Acta Cirúrgica Brasileira, 2021 Purpose: The aim of this study is to compare the hepatic protective effect of both remote and local postconditioning (POS). Methods: Twenty-eight Wistar rats were assigned into four groups: sham group(SHAM), ischemia-reperfusion group (IR), local ...
Edson Yuzur Yasojima +4 more
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Ischemic postconditioning: mechanisms, comorbidities, and clinical application
Molecular and Cellular Biochemistry, 2014 Since ischemic heart disease (IHD) is a major cause of mortality and heart failure, novel therapeutic strategies are expected to improve the clinical outcomes of patients with acute myocardial infarction. Brief episodes of ischemia/reperfusion performed at the onset of reperfusion can reduce infarct size; a phenomenon termed "ischemic postconditioning."
Buchholz, Bruno +3 more
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Hyperglycemia-induced inhibition of DJ-1 expression compromised the effectiveness of ischemic postconditioning cardioprotection in rats [PDF]
, 2013 published_or_final_versio
Lei, S.Q. +9 more
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Postconditioning as a method tissue survivability enhancement in ischemic damage
Acta Biomedica Scientifica, 2016 The article presents the present-day data on the phenomenon of ischemic myocardial postconditioning. It has been shown, that this phenomenon consists in protection of the heart from reperfusion damage by the means of short episodes of ischemia ...
M. G. Shurygin +2 more
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