Results 41 to 50 of about 8,004 (220)

Postconditioning promotes recovery in the neurovascular unit after stroke

Frontiers in Cellular Neuroscience, 2023
Background and purposeExperimental studies suggest that ischemic postconditioning interferes with cell death mechanisms and reduces infarction during the acute phase after focal cerebral ischemia.
Elga Esposito, Elga Esposito, Ester Licastro, Ester Licastro, Ornella Cuomo, Eng H. Lo, Eng H. Lo, Kazuhide Hayakawa, Giuseppe Pignataro   +8 more
doaj   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

Neurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li, Jinbo Yin, Liaoliao Li, Jiao Deng, Chenzhuo Feng, Zhiyi Zuo   +5 more
doaj   +1 more source

Pharmacological postconditioning: a molecular aspect in ischemic injury

Journal of Pharmacy and Pharmacology, 2020
Abstract Objective Ischaemia/reperfusion (I/R) injury is defined as the damage to the tissue which is caused when blood supply returns to tissue after ischaemia. To protect the ischaemic tissue from irreversible injury, various protective agents have been studied but the benefits have not been ...
Heena Khan, Ankita Kashyap, Amarjot Kaur, Thakur Gurjeet Singh   +3 more
openaire   +2 more sources

Effect of helium pre- or postconditioning on signal transduction kinases in patients undergoing coronary artery bypass graft surgery [PDF]

, 2016
Background: The noble gas helium induces pre- and postconditioning in animals and humans. Volatile anesthetics induce cardioprotection in humans undergoing coronary artery bypass graft (CABG) surgery.
Brevoord, Daniel, De Hert, Stefan, de Mol, Bas A, Hollmann, Markus W, Kerindongo, Raphaela P, Preckel, Benedikt, Schlack, Wolfgang S, Smit, Kirsten F, van Dieren, Susan, Weber, Nina C   +9 more
core   +7 more sources

High plasma concentrations of asymmetric dimethylarginine inhibit ischemic cardioprotection in hypercholesterolemic rats

Brazilian Journal of Medical and Biological Research, 2013
A low concentration of nitric oxide associated with a high concentration of asymmetric dimethylarginine (ADMA) can explain the lack of ischemic cardioprotection observed in the presence of hypercholesterolemia.
M.B.P. Landim, P.M.M. Dourado, A. Casella-Filho, A.C.P. Chagas, P.L. da-Luz   +4 more
doaj   +3 more sources

Kidney ischemia and reperfunsion syndrome: effect of lidocaine and local postconditioning

Revista do Colégio Brasileiro de Cirurgiões
Objective: to evaluate the effects of blocking the regulation of vascular tone on the ischemia and reperfusion syndrome in rats through the use of lidocaine in the postconditioning technique.
IGOR NAGAI YAMAKI, RUY VICTOR SIMÕES PONTES, FELIPE LOBATO DA SILVA COSTA, VITOR NAGAI YAMAKI, RENAN KLEBER COSTA TEIXEIRA, EDSON YUZUR YASOJIMA, MARCUS VINICIUS HENRIQUES BRITO   +6 more
doaj   +1 more source

New horizons for newborn brain protection: enhancing endogenous neuroprotection. [PDF]

, 2015
Intrapartum-related events are the third leading cause of childhood mortality worldwide and result in one million neurodisabled survivors each year. Infants exposed to a perinatal insult typically present with neonatal encephalopathy (NE).
Alonso-Alconada, D, Ezzati, M, Hassell, KJ, Hausenloy, DJ, Robertson, NJ   +4 more
core   +2 more sources

Remote Ischemic Preconditioning Neither Improves Survival nor Reduces Myocardial or Kidney Injury in Patients Undergoing Transcatheter Aortic Valve Implantation (TAVI) [PDF]

, 2020
BACKGROUND: Peri-interventional myocardial injury occurs frequently during transcatheter aortic valve implantation (TAVI). We assessed the effect of remote ischemic preconditioning (RIPC) on myocardial injury, acute kidney injury (AKIN) and 6-month ...
Flechsig, Mandy, Heidrich, Felix M., Heinzel, Frank R., Ibrahim, Karim, Linke, Axel, Pfluecke, Christian, Quick, Silvio, Ruf, Tobias F., Strasser, Ruth H., Sveric, Krunoslav M., Troeger, Willi, Wiedemann, Stephan, Winzer, Robert, Youssef, Akram, Zhang, Kun   +14 more
core   +1 more source

Combined postconditioning with ischemia and cyclosporine-A restore oxidative stress and histopathological changes in reperfusion injury of diabetic myocardium [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Chronic diabetes impedes cardioprotection in reperfusion injury and hence protecting the diabetic heart would have important outcomes.
Reza Badalzadeh, Seyed Mahmoud Tabatabaei, Mustafa Mohammadi, Arash Khaki, Dariush Mohammadnezhad   +4 more
doaj   +1 more source

Effect of ischemic postconditioning in adult valve replacement☆ [PDF]

European Journal of Cardio-Thoracic Surgery, 2008
Ischemic postconditioning (POC) by brief episodes of ischemia performed just at the time of reperfusion can reduce infarct size in animal models and clinical settings of percutaneous coronary intervention. However, the clinical applicability of postconditioning in cardiac surgery remains to be determined.
Wanjun, Luo, Bei, Li, Ri, Chen, Rimao, Huang, Guoqiang, Lin   +4 more
openaire   +2 more sources