Comparison of the effects of direct and remote ischemic post and preconditioning in the kidney of young rats: histological and laboratory evaluation [PDF]
Acta Cirúrgica BrasileiraPurpose: To evaluate the effects of direct and remote ischemic preconditioning and postconditioning on kidney ischemia–reperfusion injury in young rats.
Arthur Henrique de Almeida Oliveira +4 more
doaj +3 more sources
Perconditioning combined with postconditioning on kidney ischemia and reperfusion [PDF]
Acta Cirúrgica Brasileira, 2017 Purpose: To evaluate if combination of perconditioning and postconditioning provides improved renal protection compared to perconditioning alone in a model of renal reperfusion injury.
Felipe Lobato da Silva Costa +7 more
doaj +3 more sources
Postconditioning promotes recovery in the neurovascular unit after stroke [PDF]
Frontiers in Cellular Neuroscience, 2023 Background and purposeExperimental studies suggest that ischemic postconditioning interferes with cell death mechanisms and reduces infarction during the acute phase after focal cerebral ischemia.
Elga Esposito +8 more
doaj +2 more sources
Phosphomimetic modulation of eNOS improves myocardial reperfusion and mimics cardiac postconditioning in mice. [PDF]
PLoS ONE, 2014 Myocardial infarction resulting from ischemia-reperfusion injury can be reduced by cardiac postconditioning, in which blood flow is restored intermittently prior to full reperfusion.
Terrence Pong +4 more
doaj +3 more sources
The Perspective of Using Ischemic Tolerance in Clinical Practice [PDF]
BiomedicinesIschemic–reperfusion injury represents an extremely serious problem in the human population. It mainly affects the elderly population and currently used treatments have poor results.
Rastislav Burda +2 more
doaj +2 more sources
Delayed postconditioning protects against focal ischemic brain injury in rats. [PDF]
PLoS ONE, 2008 We and others have reported that rapid ischemic postconditioning, interrupting early reperfusion after stroke, reduces infarction in rats. However, its extremely short therapeutic time windows, from a few seconds to minutes after reperfusion, may hinder ...
Chuancheng Ren +5 more
doaj +1 more source
Protection of ischemic postconditioning against neuronal apoptosis induced by transient focal ischemia is associated with attenuation of NF-κB/p65 activation. [PDF]
PLoS ONE, 2014 Background and purposeAccumulating evidences have demonstrated that nuclear factor κB/p65 plays a protective role in the protection of ischemic preconditioning and detrimental role in lethal ischemia-induced programmed cell death including apoptosis and ...
Jianmin Liang +5 more
doaj +1 more source
Redox Report, 2023 Objectives To observe the protective effects of dexmedetomidine (Dex) postconditioning on myocardial ischemia/reperfusion injury (IRI) and to explore its potential molecular mechanisms.Methods One-hundred forty-seven male Sprague-Dawley rats were ...
Bin Hu +9 more
doaj +1 more source
Ischemic pre and postconditioning in skeletal muscle injury produced by ischemia and reperfusion in rats [PDF]
Acta Cirúrgica Brasileira, 2013 PURPOSE: To investigate the protective effects of ischemic pre and postconditioning, as well as the association of both methods, in skeletal muscle injury produced by ischemia and reperfusion in rats.
José Alves Lintz +3 more
doaj +3 more sources
Melatonin postconditioning combined with sitagliptin exerts full cardioprotection in diabetic hearts of aged rats through an AMPK-dependent mechanism [PDF]
Archives of Biological Sciences, 2021 The presence of multiple comorbidities in patients facing myocardial ischemia-reperfusion (IR) injury is the main obstacle for cardioprotection. This study investigated the effect of melatonin postconditioning combined with sitagliptin pretreatment on ...
Song Ronggang +3 more
doaj +1 more source