Results 41 to 50 of about 6,865 (203)

Exploring the role of dimethylarginine dimethylaminohydrolase-mediated reduction in tissue asymmetrical dimethylarginine levels in cardio-protective mechanism of ischaemic postconditioning in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Reperfusion of ischaemic myocardium results in reduced nitric oxide (NO) biosynthesis by endothelial nitric oxide synthase (eNOS) leading to endothelial dysfunction and subsequent tissue damage. Impaired NO biosynthesis may be partly due to
Kamaldeep Kaur, Nirmal Singh, R Dhawan
doaj   +1 more source

Isoflurane postconditioning reduces ischemia-induced nuclear factor-κB activation and interleukin 1β production to provide neuroprotection in rats and mice

Neurobiology of Disease, 2013
Application of isoflurane, a volatile anesthetic, after brain ischemia can reduce ischemic brain injury in rodents (isoflurane postconditioning). This study is designed to determine whether isoflurane postconditioning improves long-term neurological ...
Hong Li, Jinbo Yin, Liaoliao Li, Jiao Deng, Chenzhuo Feng, Zhiyi Zuo   +5 more
doaj   +1 more source

Postconditioning protects against endothelial ischemia-reperfusion injury in the human forearm [PDF]

, 2006
Background: Hypoxic cell death follows interruption of blood supply to tissues. Although successful restoration of blood flow is mandatory for salvage of ischemic tissues, reperfusion can paradoxically place tissues at risk of further injury.
MacAllister, R.J., Loukogeorgakis, S.P., Panagiotido, A.T., Yellon, D.M., Deanfield, J.E.   +4 more
core  

Design and Methodologies of the POSTconditioning during Coronary Angioplasty in Acute Myocardial Infarction (POST-AMI) Trial

, 2010
<i>Background:</i> Reperfusion remains the definitive treatment for acute myocardial infarction (AMI), but restoring blood flow carries the potential to exacerbate the ischemia-related injury. Postconditioning might modify reperfusion-induced
Luciano Babuin, Andrea Giovagnoni, Martina Zaninotto, Claudio Bilato, Pietro Renda, Flavio Mistrorigo, Giuseppe Tarantini, Enrico Favaretto, Martina Perazzolo Marra, Luisa Cacciavillani, Valeria De Biasio, Marco Panfili, Giambattista Isabella, Mario Plebani, Monica Mion, Massimo Napodano, Sabino Iliceto   +16 more
core   +3 more sources

Strongest postcondition of unstructured programs

Proceedings of the 11th International Workshop on Formal Techniques for Java-like Programs, 2009
To avoid exponential explosion, program verifiers turn the program into a passive form before generating verification conditions. A little known fact is that the passive form makes it easy to use a strongest postcondition calculus to derive the verification condition. In the first part of this paper, the passivation phase is defined precisely enough to
Grigore, R, Fairmichael, F, Charles, J, Kiniry, J   +3 more
openaire   +3 more sources

Heightened Fear Memory Retention During Infancy, but Not Number of Separation‐Induced Ultrasonic Vocalizations, Predicts a Fearful Phenotype in a Diverse Cohort of Rats

Developmental Psychobiology, Volume 68, Issue 6, November 2026.
ABSTRACT Past work using male rats, unexposed to early life adversity, suggests that number of separation‐induced ultrasonic vocalizations (USVs) and retention of an aversive association during infancy predict later individual differences in fear behavior. The present study examined these associations using male and female rats that were either exposed
Sylvia K. Harmon‐Jones, Rick Richardson   +1 more
wiley   +1 more source

Effect of sevoflurane postconditioning on myocardial oncosis and autophagy in ischemia-reperfusion injury in isolated rat heart

Bangladesh Journal of Pharmacology, 2018
The effects of sevoflurane postconditioning on myocardial oncosis and autophagy were studied in 32 isolated rat heart of ischemia-reperfusion injury.
Qi Feng Tang, Yang Xie, Hong Xie, Wen Qiang Jiang, Zhi Yuan Fang   +4 more
doaj   +1 more source

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

International Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg, Cathrine L. Lorentzen, Marie C. W. Westergaard, Trine Z. Iversen, Troels H. Borch, Marco Donia, Sigrid M. Mannering, Stine E. W. Banke, Özcan Met, Inge Marie Svane   +9 more
wiley   +1 more source

Postconditioning hormesis and the similia principle

Frontiers in Bioscience, 2009
Postexposure conditioning, as a part of hormesis, involves the application of a low dose of stress following exposure to a severe stress condition. The beneficial effect of a low level of stress in postconditioning hormesis is illustrated by a number of examples found in experimental and clinical research. Depending on whether the low-dose stress is of
van Wijk, R., Wiegant, F.A.C.
openaire   +3 more sources

The paradigm of postconditioning to protect the heart [PDF]

Journal of Cellular and Molecular Medicine, 2007
Introduction Reperfusion injury Definition of postconditioning Protective effects of postconditioning Potentiality of postconditioning Mechanisms involved in postconditioning Conclusions AbstractIschaemic preconditioning limits the damage induced by subsequent ischaemia/reperfusion (I/R).
PENNA, Claudia, MANCARDI, Daniele, RAIMONDO, Stefania, GEUNA, Stefano, PAGLIARO, Pasquale   +4 more
openaire   +3 more sources