Results 101 to 110 of about 42,902 (229)
Clinics, 2015 OBJECTIVES: Intestinal ischemia/reperfusion often leads to acute lung injury and multiple organ failure. Ischemic preconditioning is protective in nature and reduces tissue injuries in animal and human models.
Muhammad Tahir +6 more
doaj +1 more source
Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-kinase-akt pathway [PDF]
, 2004 Brief intermittent episodes of ischemia and reperfusion, at the onset of reperfusion after a prolonged period of ischemia, confer cardioprotection, a phenomenon termed "ischemic postconditioning" (Postcond).
Hausenloy, D.J. +3 more
core
Regulation of gap junction function; the role of nitric oxide. [PDF]
, 2013 Myocardial ischemia resulting from sudden occlusion of a coronary artery is one of the major causes in the appearance of severe, often life-threatening ventricular arrhythmias.
Gönczi, Márton +3 more
core +2 more sources
Experimental Physiology, EarlyView.Abstract Cardiosphere‐derived cells (CDCs) are a promising in vitro model for studying myocardial ischaemia–reperfusion (I–R) injury and testing potential therapeutic interventions. This study investigated the suitability of CDCs as a model for myocardial infarction (MI) and the effects of prolyl hydroxylase inhibitor (PHI) administration during ...
Luca Salhöfer +4 more
wiley +1 more source
Cardiology Plus, 2018 Ischemic preconditioning is a protective phenomenon, by which brief ischemic stimuli in a vascular bed are able to counteract the damage from a longer subsequent ischemia.
Elpidio Santillo +1 more
doaj +1 more source
Protection Against Cardiac Injury by Small Ca\u3csup\u3e2 +\u3c/sup\u3e-Sensitive K\u3csup\u3e+\u3c/sup\u3e Channels Identified in Guinea Pig Cardiac Inner Mitochondrial Membrane [PDF]
, 2013 We tested if small conductance, Ca2 +‐sensitive K+ channels (SKCa) precondition hearts against ischemia reperfusion (IR) injury by improving mitochondrial (m) bioenergetics, if O2‐derived free radicals are required to initiate protection via SKCa ...
Aldakkak, Mohammed +9 more
core +1 more source
The route and timing of hydrogen sulfide therapy critically impacts intestinal recovery following ischemia and reperfusion injury [PDF]
, 2018 PURPOSE: Hydrogen sulfide (H2S) has many beneficial properties and may serve as a novel treatment in patients suffering from intestinal ischemia-reperfusion injury (I/R).
Drucker, Natalie A. +4 more
core +1 more source
Ischemic Preconditioning in Isolated Cells [PDF]
Circulation Research, 2000 Ischemic preconditioning describes the increased resistance to myocardial infarction that follows short sublethal periods of ischemia. After the ischemia that triggers preconditioning, there are 2 phases of protection: an early (short-lived) phase termed early or classic preconditioning1 and a late (more prolonged) phase termed late preconditioning or ...
openaire +2 more sources
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti +2 more
wiley +1 more source
Clinics, 2012 OBJECTIVE: Ischemic preconditioning and some drugs can protect tissues from injury by preserving microcirculation. This study evaluated vascular permeability in a hamster cheek pouch preparation using either short ischemic periods or bradykinin as ...
Fabiana Gomes da Conceição +4 more
doaj +1 more source