Results 91 to 100 of about 692 (163)

ISKNV ORF111L and zebrafish TRAF2 overexpression resulted in caspase 8 and caspase 3 upregulation.

, 2013
(A–B) The caspase 8 or caspase 3 expression was shown in wild type embryos by whole mount RNA in situ hybridization assay. (C–D) ISKNV ORF111L overexpression resulted in significant caspase 8 (C, arrow) and caspase 3 (D, arrow head) upregulation.
Jun-Feng Xie (323228), Xiao-Qiang Yu (148359), Shao-Ping Weng (148356), Bai-Liang He (323222), Lu-Yun Yang (323226), Jian-Guo He (148364), Ji-Min Yuan (323224)   +6 more
core   +1 more source

Time-Series Transcriptomics of a Gill Cell Line (BTG) from Chinese Bahaba (Bahaba taipingensis) During ISKNV Infection (3–24 hpi)

Fishes
The Chinese bahaba (Bahaba taipingensis), an endangered marine fish, is highly vulnerable to infectious spleen and kidney necrosis virus (ISKNV). In this work, we developed a gill filament-derived cell line, designated BTG, to investigate how these cells
Chenfei Guo, Zhihong Gong, Fei Fang, Xihong Li, Lei Wang, Na Wang, Zhangfan Chen, Lin Yan, Kuoqiu Yan, Guobin Hu, Songlin Chen   +10 more
doaj   +1 more source

The viral ankyrin repeat protein (ORF124L) from infectious spleen and kidney necrosis virus attenuates nuclear factor-κB activation and interacts with IκB kinase β

, 2011
The ankyrin (ANK) repeat is one of the most common protein–protein interaction motifs, found predominantly in eukaryotes and bacteria, but the functions of the ANK repeat are rarely researched in animal viruses, with the exception of poxviruses ...
Li-Shi Yang, Jian-Guo He, Shao-Ping Weng, Chang-Jun Guo, Xiao-Qiang Yu, Li-Qun Yuan, Wei-Jian Chen   +6 more
core   +1 more source

Global Landscape of Structural Proteins of Infectious Spleen and Kidney Necrosis Virus

, 2011
Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus in the family Iridoviridae , causes severe damage to mandarin fish cultures in China. Little is
Jian-Guo He, Shao-Ping Weng, Ye Zhang, Fan Shuang, Jing Zhang, Yong-wen Luo, Xiao-Peng Xiong, Chuan-Fu Dong   +7 more
core   +1 more source

Carbon Nanotube-Based Drug Delivery System Increases Drug Content and Promotes Immune Response in Mandarin Fish

Fishes
A number of viral diseases have significantly impeded the growth of the aquaculture industry. Antiviral drugs represent an effective means of controlling infection.
Yijun Jia, Zhao Zhao, Leyang Chen, Yongqi Liu, Bin Zhu   +4 more
doaj   +1 more source

Molecular mechanism of infectious spleen and kidney necrosis virus in manipulating the hypoxia-inducible factor pathway to augment virus replication

Infectious spleen and kidney necrosis virus (ISKNV), a member of the genus Megalocytivirus in the family Iridoviridae, can infect over fifty fish species and cause significant economic losses in Asia.
jian He (18327468)
core   +1 more source

Deteksi dan Karakterisasi Megalocytivirus pada Budidaya Ikan di Beberapa Daerah di Indonesia

, 2020
Megalocytivirus termasuk ke dalam anggota famili Iridoviridae dan menyebabkan kerugian ekonomi yang sangat tinggi pada budidaya ikan. Megalocytivirus memiliki tiga spesies yaitu Infectious Spleen and Kidney Necrosis Virus (ISKNV), Red Sea Bream ...
Rifai, Achmad Bahtiar
core  

ISKNV-pORF71 hijacks outer mitochondrial membrane-localized VDAC2 to the nucleus, enhancing apoptosis by disrupting mitochondrial membrane permeability

Abstract Infectious spleen and kidney necrosis virus (ISKNV), the type species of the genus Megalocytivirus within the family Iridoviridae, is one of the most devastating pathogens affecting global teleost populations.
He-tong Zhang, Yuting Fu, Youyong Dong, Hemei Qi, Shaoping Weng, Jianguo He, Chuanfu Dong   +6 more
openaire   +1 more source

The microalga Chlamydomonas reinhardtii as a cell factory for subunit vaccine production against the fish pathogen Infectious Spleen and Kidney Necrosis Virus

Infectious Spleen and Kidney Necrosis Virus (ISKNV) causes severe disease in commercially important fish, with potential mortality reaching 100 % in susceptible species.
Purton, Saul, Saksmerprome, Vanvimon, Jitrakorn, Sarocha, Kusolkumbot, Pokchut, Yodchan, Varakul, Charoonnart, Patai, Ounjai, Puey   +6 more
core  

Epidemiological surveillance reveals major pathogen dynamics in Brazilian Nile tilapia aquaculture from 2023 to 2025. [PDF]

Front Vet Sci
Cardoso-Guimarães M, Fernandez-Alarcon MF, Correa R, Miyoko-Natori M, Galetti R, Brito de Souza A, Squizatto AC, Silva R, Araújo de Almeida L, Mota Sátiro T, Ildefonso R, Rozas-Serri M.   +11 more
europepmc   +1 more source