Results 131 to 140 of about 121,748 (297)
Streptozotocin induced hyperglycemia in the axolotl
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen+2 more
wiley +1 more source
Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen+7 more
wiley +1 more source
ADENOMA OF THE ISLETS OF LANGERHANS, WITH HYPERINSULINISM, ASSOCIATED WITH ADENOMA OF THE THYROID
D. P. GREENLEE+3 more
openalex +2 more sources
Cardioprotective effects of semaglutide on isolated human ventricular myocardium
Semaglutide reduces late sodium current (INa) and diastolic calcium (Ca) sparks in human cardiomyocytes from aortic stenosis (AS) and end‐stage heart failure with reduced ejection fraction (HFrEF) patients, thereby increasing Ca transients. Improved Ca storage may underly the enhanced contractility of human cardiomyocytes upon semaglutide.
Thomas Krammer+16 more
wiley +1 more source
The functional significance of a spontaneous pancreatic islet change in aged rats [PDF]
A. Hajdu, Fiona Herr, G Róna
openalex +1 more source
Abstract Metabolic syndrome (MetS) is a complex noncommunicable condition characterized by central obesity, insulin resistance, hyperlipidemia, hypertension, and hyperglycemia. Epidemiological evidence shows that MetS affects a third of the global population; however, due to its complex pathogenesis and limited drug therapy options, the increasing ...
Josiah Owuor Oyalo+3 more
wiley +1 more source
ABSTRACT This study examines the effect of climate change exposure on analysts' forecasted stock performance operationalized by their actual recommendations. Our results indicate that firms with higher exposure to climate change receive less favorable recommendations from analysts.
Cyrine Khiari+4 more
wiley +1 more source
Carbohydrate metabolism in pancreatic islets and the release of insulin [PDF]
P J Randle, S. J. H. Ashcroft
openalex +1 more source