Results 81 to 90 of about 10,923 (183)
Fibrillar dimer formation of islet amyloid polypeptides
AIP Advances, 2015 Amyloid deposits of human islet amyloid polypeptide (hIAPP), a 37-residue hormone co-produced with insulin, have been implicated in the development of type 2 diabetes.
Chi-cheng Chiu, Juan J. de Pablo
doaj +1 more source
Nature Communications, 2018 Toxic gain-of-function by islet amyloid polypeptide (IAPP) is thought to be mediated by membrane poration. Here the authors develop diluted-FRET to show that changes in pore structure correlate with onset of toxicity inside insulin secreting cells.
Melissa Birol +3 more
doaj +1 more source
Nanoscale Control of Amyloid Self-Assembly Using Protein Phase Transfer by Host-Guest Chemistry
Scientific Reports, 2017 Amyloid fibrils have recently been highlighted for their diverse applications as functional nanomaterials in modern chemistry. However, tight control to obtain a targeted fibril length with low heterogeneity has not been achieved because of the ...
Tae Su Choi +5 more
doaj +1 more source
Cell Transplantation, 2008 To learn more about nonimmune-mediated islet graft failure, we transplanted different preparations (preps) of isolated human islets under the kidney capsule of streptozotocin (STZ)-diabetic nude mice.
Alberto M. Davalli M.D. +11 more
doaj +1 more source
A small molecule improves diabetes in mice expressing human islet amyloid polypeptide. [PDF]
Islets, 2023 Bhagat V, Verchere CB.
europepmc +1 more source
A pancreatic player in dementia: pathological role for islet amyloid polypeptide accumulation in the brain. [PDF]
Neural Regen Res, 2023 Bortoletto AS, Parchem RJ.
europepmc +1 more source
Studies on alpha-synuclein and islet amyloid polypeptide interaction. [PDF]
Front Mol Biosci, 2023 Wang Y +3 more
europepmc +1 more source
The potential role of human islet amyloid polypeptide in type 2 diabetes mellitus and Alzheimer's diseases. [PDF]
Diabetol Metab Syndr, 2023 Alrouji M +6 more
europepmc +1 more source