Results 1 to 10 of about 21,603 (207)

Azelaic acid reduces arsenic-induced toxicity and inflammation in the rat islets of langerhans [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Arsenic is classified as a toxic metal that is naturally found in the Earth’s crust, and long-term exposure to it can result in chronic human disorders like cancer and diabetes.
Sara Mostafalou, Fatemeh Moafi-Madani, Maryam Baeeri, Mahban Rahimifard, Hamed Haghi-Aminjan   +4 more
doaj   +2 more sources

A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model [PDF]

Life
Producing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Victor I. Sevastianov, Anna S. Ponomareva, Natalia V. Baranova, Aleksandra D. Belova, Lyudmila A. Kirsanova, Alla O. Nikolskaya, Eugenia G. Kuznetsova, Elizaveta O. Chuykova, Nikolay N. Skaletskiy, Galina N. Skaletskaya, Evgeniy A. Nemets, Yulia B. Basok, Sergey V. Gautier   +12 more
doaj   +2 more sources

Potential of [11C]UCB-J as a PET tracer for islets of Langerhans [PDF]

Scientific Reports, 2021
Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Emmi Puuvuori, Johanna Rokka, Per-Ola Carlsson, Zhanchun Li, Jonas Eriksson, Olof Eriksson   +5 more
doaj   +2 more sources

Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse [PDF]

International Journal of Hepatology, 2020
Background. The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. Meanwhile, the main component of cloves that produce antioxidant effects is eugenol.
Ali Akbar Oroojan, Narges Chenani, Marzieh An’aam   +2 more
doaj   +2 more sources

Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus

Biomedicines, 2022
Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady, Amal M. Alzahrani, Hayam Elshazly, Eman Abdullah Alshehri, Majed H. Wakid, Hattan S. Gattan, Wafa Abdullah I. Al-Megrin, Mashael S. Alfaifi, Khalil Mohamed, Waheeb Alharbi, Hatem A. Elshabrawy, Salwa S. Younis   +11 more
doaj   +1 more source

In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans

Вестник трансплантологии и искусственных органов, 2022
The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva, N. V. Baranova, I. A. Miloserdov, V. I. Sevastianov   +3 more
doaj   +1 more source

Morphofunctional condition of the pancreatic insular apparatus in old rats with alloxan-induced diabetes and its correction with lipoic acid

BIO Web of Conferences, 2020
The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia, Danilova Irina, Emelianov Viktor, Gette Irina, Trofimova Ekaterina   +4 more
doaj   +1 more source

Are physiological oscillations physiological?

The Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice [PDF]

Veterinary World, 2020
Background and Aim: At present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings.
S. Suhariningsih, Suryani Dyah Astuti, Saikhu Akhmad Husen, Dwi Winarni, Dian Astri Rahmawati, Akhmad Taufiq Mukti, Alfian Pramudita Putra, Muhammad Miftahussurur   +7 more
doaj   +1 more source

Protecting islet functional viability using mesenchymal stromal cells

Stem Cells Translational Medicine, 2021
Islet transplantation is an emerging treatment for type 1 diabetes which offers the prospect of physiological control of blood glucose and reductions in acute hypoglycaemic episodes.
Ella L. Hubber, Chloe L. Rackham, Peter M. Jones   +2 more
doaj   +1 more source