Azelaic acid reduces arsenic-induced toxicity and inflammation in the rat islets of langerhans [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Arsenic is classified as a toxic metal that is naturally found in the Earth’s crust, and long-term exposure to it can result in chronic human disorders like cancer and diabetes.
Sara Mostafalou +4 more
doaj +2 more sources
A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model [PDF]
LifeProducing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Victor I. Sevastianov +12 more
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Potential of [11C]UCB-J as a PET tracer for islets of Langerhans [PDF]
Scientific Reports, 2021 Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Emmi Puuvuori +5 more
doaj +2 more sources
Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse [PDF]
International Journal of Hepatology, 2020 Background. The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. Meanwhile, the main component of cloves that produce antioxidant effects is eugenol.
Ali Akbar Oroojan +2 more
doaj +2 more sources
Blockade but not overexpression of the junctional adhesion molecule C influences virus-induced type 1 diabetes in mice [PDF]
, 2013 Type 1 diabetes (T1D) results from the autoimmune destruction of insulin-producing beta-cells in the pancreas. Recruitment of inflammatory cells is prerequisite to beta-cell-injury.
Aurrand-Lions, Michel +10 more
core +9 more sources
Biomedicines, 2022 Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady +11 more
doaj +1 more source
Вестник трансплантологии и искусственных органов, 2022 The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva +3 more
doaj +1 more source
BIO Web of Conferences, 2020 The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia +4 more
doaj +1 more source
The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice [PDF]
Veterinary World, 2020 Background and Aim: At present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings.
S. Suhariningsih +7 more
doaj +1 more source
Macrophages in endocrine glands, with emphasis on pancreatic islets [PDF]
, 2016 We review here the macrophages found in endocrine tissues, placing emphasis on those residing in the islets of Langerhans of the pancreas. The islets represent the endocrine organ where macrophages have been examined in great detail and where our own ...
Unanue, Emil R
core +2 more sources