Results 11 to 20 of about 32,122 (266)

Transplantation or islets of Langerhans: new developments

open access: yesSwiss Medical Weekly, 2001
The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes.
A Caulfield   +4 more
doaj   +3 more sources

Hyperglycemia impairs EAAT2 glutamate transporter trafficking and glutamate clearance in islets of Langerhans: implications for type 2 diabetes pathogenesis and treatment. [PDF]

open access: greenAm J Physiol Endocrinol Metab
Galli A   +13 more
europepmc   +2 more sources

Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus

open access: yesBiomedicines, 2022
Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady   +11 more
doaj   +1 more source

In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans

open access: yesВестник трансплантологии и искусственных органов, 2022
The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva   +3 more
doaj   +1 more source

Morphofunctional condition of the pancreatic insular apparatus in old rats with alloxan-induced diabetes and its correction with lipoic acid

open access: yesBIO Web of Conferences, 2020
The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia   +4 more
doaj   +1 more source

Are physiological oscillations physiological?

open access: yesThe Journal of Physiology, EarlyView., 2023
Abstract figure legend Mechanisms and functions of physiological oscillations. Abstract Despite widespread and striking examples of physiological oscillations, their functional role is often unclear. Even glycolysis, the paradigm example of oscillatory biochemistry, has seen questions about its oscillatory function.
Lingyun (Ivy) Xiong, Alan Garfinkel
wiley   +1 more source

The combined effect of magnetic and electric fields using on/off infrared light on the blood sugar level and the diameter of Langerhans islets of diabetic mice [PDF]

open access: yesVeterinary World, 2020
Background and Aim: At present, diabetes is treated with oral antidiabetic medicines, such as sulfonylureas and thiazolidine, as well as insulin injection. However, these methods have several shortcomings.
S. Suhariningsih   +7 more
doaj   +1 more source

Protecting islet functional viability using mesenchymal stromal cells

open access: yesStem Cells Translational Medicine, 2021
Islet transplantation is an emerging treatment for type 1 diabetes which offers the prospect of physiological control of blood glucose and reductions in acute hypoglycaemic episodes.
Ella L. Hubber   +2 more
doaj   +1 more source

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