Results 11 to 20 of about 21,603 (207)

Bulk Cryopreservation of Isolated Islets of Langerhans

open access: yesCell Transplantation, 1996
Current methods to isolate human islets of Langerhans are limited and multiple donors are required for successful reversal of longstanding Type 1 diabetes mellitus. Cryopreservation of isolated islets is an effective method of storing and pooling islets.
Jonathan R.T. Lakey   +3 more
doaj   +4 more sources

An Autonomous Cannabinoid System in Islets of Langerhans. [PDF]

open access: yesFront Endocrinol (Lausanne), 2021
While endocannabinoids (ECs) and cannabis were primarily studied for their nervous system effects, it is now clear that ECs are also produced in the periphery where they regulate several physiological processes, including energy storage, glucose and lipid metabolism, insulin secretion and synthesis, and hepatocyte function.
Aseer KR, Egan JM.
europepmc   +6 more sources

The Cells of the Islets of Langerhans. [PDF]

open access: yesJ Clin Med, 2018
Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non-β islet cells in to insulin-producing β-cells to replenish β-cell mass as a means to treat diabetes.
Da Silva Xavier G.
europepmc   +6 more sources

Differentiation of pancreatic endocrine islets in buffalo fetus

open access: yesIndian Journal of Animal Sciences, 2020
Pancreas of 24 buffalo foetii collected from abattoir and veterinary clinics, GADVASU, Ludhiana were studied. The buffalo foetii were divided into three groups after measuring their CVRL, viz.
DIVYA GUPTA   +3 more
doaj   +1 more source

Surface Coating of Islets of Langerhans by Activated Polyethylene Glycol [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2008
The final treatment for diabetes is transplantation of islets of Langerhans. One of the new proposed methods for immunological preservation of transplanted cells is coating of cell surface by polyethylene glycol.
S. Hashemi Najafabadi   +3 more
doaj   +1 more source

The pancreatic islet: a micro-organ in control [PDF]

open access: yesCellR4, 2021
The islets of Langerhans constitute the endocrine pancreas which regulates blood glucose homeostasis and islet dysfunction results in diabetes. Each of the pancreatic islets constitutes an entire micro-organ with intricate cell to cell interactions and ...
M. Abdulreda, P. Berggren
doaj   +1 more source

Multipotent mesenchymal stromal cells enhance insulin secretion from human islets via N-cadherin interaction and prolong function of transplanted encapsulated islets in mice

open access: yesStem Cell Research & Therapy, 2017
Background Multipotent mesenchymal stromal cells (MSC) enhance viability and function of islets of Langerhans. We aimed to examine the interactions between human MSC and human islets of Langerhans that influence the function of islets.
Elisa Montanari   +7 more
doaj   +1 more source

Transplante isogênico de ilhotas de Langerhans no fígado de ratos: metodologia para separação e purificação das ilhotas de Langerhans Isogenic islet transplantation on the rat liver: Method for isolation and purification of the rat islets

open access: yesArquivos de Gastroenterologia, 2000
A maior indicação do transplante de pâncreas ou de ilhotas de Langerhans é o diabetes mellitus do tipo I. O processo deve suprir as necessidades de insulina mantendo os níveis glicêmicos dentro da normalidade.
Eleazar CHAIB   +3 more
doaj   +1 more source

Laser Capture Microdissection Coupled Capillary Immunoassay to Study the Expression of PCK-2 on Spatially-Resolved Islets of Rat Langerhans

open access: yesPharmaceutics, 2021
The platform for precise proteomic profiling of targeted cell populations from heterogeneous tissue sections is developed. We demonstrate a seamless and systematic integration of LCM with an automated cap-IA for the handling of a very small-sized ...
Shashank Pandey   +5 more
doaj   +1 more source

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