Results 11 to 20 of about 39,685 (253)

A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model. [PDF]

open access: yesLife (Basel)
Producing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Sevastianov VI   +12 more
europepmc   +2 more sources

Potential of [11C]UCB-J as a PET tracer for islets of Langerhans. [PDF]

open access: yesSci Rep, 2021
Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Puuvuori E   +5 more
europepmc   +2 more sources

Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse. [PDF]

open access: yesInt J Hepatol, 2020
Background. The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. Meanwhile, the main component of cloves that produce antioxidant effects is eugenol.
Oroojan AA, Chenani N, An'aam M.
europepmc   +2 more sources

Transplantation or islets of Langerhans: new developments

open access: yesSwiss Medical Weekly, 2001
The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes.
Berney, Thierry   +8 more
openaire   +6 more sources

Isolation of Adult Porcine Islets of Langerhans

open access: yesCell Transplantation, 2000
While human islet allotransplantation is limited due to the shortage of donors, pig islet xenotransplantation appears to be a possible alternative. Enzymatic digestion is the method most commonly used for adult pig islet isolation, but since the description of the semiautomated isolation technique in the late 1980s, yields of pig islet isolations have
Toso, Christian   +5 more
openaire   +5 more sources

Bulk cryopreservation of isolated islets of Langerhans

open access: yesCell Transplantation, 1996
Current methods to isolate human islets of Langerhans are limited and multiple donors are required for successful reversal of longstanding Type 1 diabetes mellitus. Cryopreservation of isolated islets is an effective method of storing and pooling islets.
Jonathan R. T. Lakey   +3 more
openaire   +4 more sources

Pancreatic Pathological Changes in Murine Toxoplasmosis and Possible Association with Diabetes Mellitus

open access: yesBiomedicines, 2022
Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady   +11 more
doaj   +1 more source

In vitro effect of bioscaffolds on viability and insulin‑producing function of human islets of Langerhans

open access: yesВестник трансплантологии и искусственных органов, 2022
The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva   +3 more
doaj   +1 more source

Morphofunctional condition of the pancreatic insular apparatus in old rats with alloxan-induced diabetes and its correction with lipoic acid

open access: yesBIO Web of Conferences, 2020
The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia   +4 more
doaj   +1 more source

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