Results 11 to 20 of about 39,685 (253)
A Tissue-Engineered Construct Based on a Decellularized Scaffold and the Islets of Langerhans: A Streptozotocin-Induced Diabetic Model. [PDF]
Producing a tissue-engineered pancreas based on a tissue-specific scaffold from a decellularized pancreas, imitating the natural pancreatic tissue microenvironment and the islets of Langerhans, is one of the approaches to treating patients with type 1 ...
Sevastianov VI+12 more
europepmc +2 more sources
Potential of [11C]UCB-J as a PET tracer for islets of Langerhans. [PDF]
Biomarkers for the measurement of islets of Langerhans could help elucidate the etiology of diabetes. Synaptic vesicle glycoprotein 2 A (SV2A) is a potential marker reported to be localized in the endocrine pancreas.
Puuvuori E+5 more
europepmc +2 more sources
Antioxidant Effects of Eugenol on Oxidative Stress Induced by Hydrogen Peroxide in Islets of Langerhans Isolated from Male Mouse. [PDF]
Background. The antioxidant system in islets of Langerhans is weak, which can lead to diabetes. Meanwhile, the main component of cloves that produce antioxidant effects is eugenol.
Oroojan AA, Chenani N, An'aam M.
europepmc +2 more sources
Transplantation or islets of Langerhans: new developments
The clinical results recently reported by the Edmonton group in recipients of allogeneic islet grafts, all of whom achieved at least temporary insulin independence, has rekindled interest in transplantation of islets of Langerhans as a means to cure diabetes.
Berney, Thierry+8 more
openaire +6 more sources
Isolation of Adult Porcine Islets of Langerhans
While human islet allotransplantation is limited due to the shortage of donors, pig islet xenotransplantation appears to be a possible alternative. Enzymatic digestion is the method most commonly used for adult pig islet isolation, but since the description of the semiautomated isolation technique in the late 1980s, yields of pig islet isolations have
Toso, Christian+5 more
openaire +5 more sources
Bulk cryopreservation of isolated islets of Langerhans
Current methods to isolate human islets of Langerhans are limited and multiple donors are required for successful reversal of longstanding Type 1 diabetes mellitus. Cryopreservation of isolated islets is an effective method of storing and pooling islets.
Jonathan R. T. Lakey+3 more
openaire +4 more sources
The milieu interieur and the islets of Langerhans [PDF]
Roger H. Unger
openaire +4 more sources
Background: Previous studies have reported involvement of Toxoplasma gondii (T. gondii) infections in the pathogenesis of some autoimmune diseases, such as polymyositis, rheumatoid arthritis, autoimmune thyroiditis, and Crohn’s disease.
Asmaa M. El-kady+11 more
doaj +1 more source
The culture of islets of Langerhans with bioscaffolds – extracellular matrix (ECM) mimetics – can provide a native microenvironment suitable for islets. This is one of the main conditions for creating a pancreatic tissue equivalent.Objective: to compare ...
A. S. Ponomareva+3 more
doaj +1 more source
The concentration of glucose and glycosylated hemoglobin in the blood of animals increases as a result of physiological aging. This is due to damage to the pancreatic insular apparatus and a decrease in the number and functioning of active β-cells.
Klyueva Yulia+4 more
doaj +1 more source