Results 31 to 40 of about 39,022 (224)
Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]
, 1984 Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens +35 more
core +4 more sources
Size Distribution of Mouse Langerhans Islets [PDF]
Biophysical Journal, 2007 Pancreatic beta-cells are clustered in islets of Langerhans, which are typically a few hundred micrometers in a variety of mammals. In this study, we propose a theoretical model for the growth of pancreatic islets and derive the islet size distribution, based on two recent observations: First, the neogenesis of new islets becomes negligible after some ...
Jo, Junghyo +2 more
openaire +2 more sources
Неонатологія, хірургія та перинатальна медицинаThe study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович +3 more
doaj +1 more source
Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices
Cell Transplantation, 1992 In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao +3 more
doaj +1 more source
Negative Feedback Synchronizes Islets of Langerhans [PDF]
Biophysical Journal, 2014 Insulin is released from the pancreas in pulses with a period of ~ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified oscillations of insulin secretion?
Dhumpa, Raghuram +4 more
openaire +2 more sources
Вестник трансплантологии и искусственных органовThe creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I ...
N. V. Baranova +6 more
doaj +1 more source
Cyclic AMP signalling in pancreatic islets [PDF]
, 2010 Cyclic 3'5'AMP (cAMP) is an important physiological amplifier of glucose-induced insulin secretion by the pancreatic islet β-cell, where it is formed by the activity of adenylyl cyclases, which are stimulated by glucose, through elevation in ...
Furman, Brian +2 more
core +1 more source
The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line [PDF]
Iranian Journal of Basic Medical Sciences, 2017 Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin
Mandana Mahmoodzaeh Sagheb +2 more
doaj +1 more source
Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement [PDF]
, 1990 Nine patients who became diabetic after upper-abdominal exenteration and liver transplantation were given pancreatic islet-cell grafts obtained from the liver donor (eight cases), a third-party donor (one), or both (four). Two patients were diabetic when
Alejandro, R +8 more
core +1 more source
Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas AirlanggaIntroduction: Calorie consumption that exceeds normal limits each year can be a risk factor in causing diabetes mellitus (DM). This condition causes the body to be in a state of hyperglycemia, which will trigger changes in the diameter and number of ...
Eny Wulan Sari +3 more
doaj +1 more source