Results 31 to 40 of about 32,122 (266)
One thousand faces of langerhans islets [PDF]
International journal of pancreatology, 1999 Studies with different strains of Syrian hamsters and Syrian golden hamsters have revealed the remarkable potential of islet cells to undergo orthotopic and heterotopic metaplasia. The most common spontaneous change included the development of hepatocytes in aged and malnourished hamsters.
Pour, Parviz, Schmied, Bruno
openaire +4 more sources
Insulin Treatment of Mice Recipients Preserves β-Cell Function in Porcine Islet Transplantation
Cell Transplantation, 2002 Encapsulation of islets of Langerhans confers protection against cell-mediated immune destruction and so should allow the transplantation of islets without immunosuppression.
Oleg Pakhomov +5 more
doaj +1 more source
Pharmaceutics, 2021 The platform for precise proteomic profiling of targeted cell populations from heterogeneous tissue sections is developed. We demonstrate a seamless and systematic integration of LCM with an automated cap-IA for the handling of a very small-sized ...
Shashank Pandey +5 more
doaj +1 more source
مجله دانشکده پزشکی اصفهان, 2020 Background: Diabetes is caused by a breakdown in insulin production or its malfunction in the body. So far, many studies have been done on its treatment.
Ebrahim Esfandiari +4 more
doaj +1 more source
Scientific Reports, 2016 It has been recently proposed that exposure to polychlorinated biphenyls (PCBs) is a risk factor to type 2 diabetes mellitus (DM2). We investigated this hypothesis using long-term in vivo PCB126 exposure to rats addressing metabolic, cellular and ...
R. Loiola +9 more
semanticscholar +1 more source
Size Distribution of Mouse Langerhans Islets [PDF]
Biophysical Journal, 2007 Pancreatic beta-cells are clustered in islets of Langerhans, which are typically a few hundred micrometers in a variety of mammals. In this study, we propose a theoretical model for the growth of pancreatic islets and derive the islet size distribution, based on two recent observations: First, the neogenesis of new islets becomes negligible after some ...
Jo, Junghyo +2 more
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Неонатологія, хірургія та перинатальна медицинаThe study of pathohistological and morphofunctional changes in the endocrine pancreas is an integral part of experimental diabetology, which allows obtaining a signifi cant amount of information on various aspects of the etiology and pathogenesis of ...
О. Оленович +3 more
doaj +1 more source
Entrapment of Cultured Pancreas Islets in Three-Dimensional Collagen Matrices
Cell Transplantation, 1992 In vitro culture of islets of Langerhans decreases their immunogenecity, presumably by eliminating passenger leukocytes and other Ia+ presenting cells within the islets.
Seh-Huang Chao +3 more
doaj +1 more source
Negative Feedback Synchronizes Islets of Langerhans [PDF]
Biophysical Journal, 2014 Insulin is released from the pancreas in pulses with a period of ~ 5 min. These oscillatory insulin levels are essential for proper liver utilization and perturbed pulsatility is observed in type 2 diabetes. What coordinates the many islets of Langerhans throughout the pancreas to produce unified oscillations of insulin secretion?
Dhumpa, Raghuram +4 more
openaire +2 more sources
Вестник трансплантологии и искусственных органовThe creation of a cell-engineered pancreatic construct (CEPC) from islets of Langerhans and biocompatible matrix carrier (framework/scaffold), which imitates the native microenvironment of pancreatic tissue, is an approach to the treatment of type I ...
N. V. Baranova +6 more
doaj +1 more source