Results 51 to 60 of about 39,022 (224)

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

Developmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito, Yukio Fujiwara, Yasuka L. Yamaguchi, Satomi S. Tanaka, Kyoko Miura, Yoshiyuki Hizukuri, Kyoko Yamashiro, Yasuhiro Hayashi, Yuta Nakashima, Yoshihiro Komohara   +9 more
wiley   +1 more source

Effect of Ganoderma lucidum hydroalcoholic extract on insulin release in rat-isolated pancreatic islets [PDF]

Avicenna Journal of Phytomedicine, 2012
Objective: Ganoderma Lucidum (G. Lucidum) has been suggested to increase serum insulin level.This study was undertaken to investigateits direct effect on the islets of Langerhans.
Reza Shafiee-Nick, Seyyed Mohammad Reza Parizadeh, Nona Zokaei, Ahmad Ghorbani   +3 more
doaj  

Zmiz1 is required for mature β-cell function and mass expansion upon high fat feeding

Molecular Metabolism, 2022
Objective: Identifying the transcripts which mediate genetic association signals for type 2 diabetes (T2D) is critical to understand disease mechanisms. Studies in pancreatic islets support the transcription factor ZMIZ1 as a transcript underlying a T2D ...
Tamadher A. Alghamdi, Nicole A.J. Krentz, Nancy Smith, Aliya F. Spigelman, Varsha Rajesh, Alokkumar Jha, Mourad Ferdaoussi, Kunimasa Suzuki, Jing Yang, Jocelyn E. Manning Fox, Han Sun, Zijie Sun, Anna L. Gloyn, Patrick E. MacDonald   +13 more
doaj   +1 more source

The Antidiabetic Activity of Curry Leaves “Murraya Koenigii” on the Glucose Levels, Kidneys, and Islets of Langerhans of Rats with Streptozotocin Induced Diabetes [PDF]

, 2017
Background: The aims of this study were to explore the antihyperglycemic effect of curry leaves, Murraya koenigii "MK" aqueous extract, and to examine its possible protective effects on the islets of Langerhans and kidneys of streptozotocin (STZ ...
Al-Ani, I. M. (Imad), Alazzawi, K. S. (Khalid), Santosa, R. I. (Rahajoe), Saxena, A. K. (Anil), Yankuzo, M. H. (Muhammad)   +4 more
core  

Islets of Langerhans Are Protected from Inflammatory Cell Recruitment during Reperfusion of Rat Pancreas Grafts [PDF]

, 2010
Background: Ischemia/reperfusion (I/R) injury plays a pivotal role in the development of graft pancreatitis, with ischemia time representing one of its crucial factors.
Eichhorn, M. E., Löhe, F., Massberg, S., Messmer, K., Preissler, G., Waldner, H., Winter, H.   +6 more
core   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Simvastatin Rapidly and Reversibly Inhibits Insulin Secretion in Intact Single-Islet Cultures [PDF]

, 2016
open10Epidemiological studies suggest that statins may promote the development or exacerbation of diabetes, but whether this occurs through inhibition of insulin secretion is unclear.
Alessandro Zambon, Angelo Avogaro, Camilla Luni, Catalin Dacian Ciubotaru, Fabio Mammano, Gian Paolo Fadini, Nicola Elvassore, Onelia Gagliano, Silvia Galvanin, Valentina Scattolini   +9 more
core   +2 more sources

Nutraceutical Evaluation of Biscuits Formulated From Acha, Chia, and Soycake Flours on Glycemic Control, Lipid Profile, and Histopathological Effects in High‐Fat Diet/Streptozotocin‐Induced Type 2 Diabetic Rats

Food Chemistry International, EarlyView.
Acha–chia–soycake biscuits improved glucose tolerance, lipid profile, insulin levels, and pancreatic integrity in HFD–STZ diabetic rats. ACSB1 and ACSB13 outperformed acarbose, showing potent antihyperglycemic, hypolipidemic, and pancreatic‐protective effects.
Oluwafunmilayo Christianah Ogunnowo, Olufunmilayo Sade Omoba, Aderonke Ibidunni Olagunju, Olamide Wilson Fasakin, Idowu Sunday Oyeleye, Olajide Raymond Ojo   +5 more
wiley   +1 more source

Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]

, 1993
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
DJ Garry, GF Bottazzo, GF Bottazzo, GS Eisenbarth, J Satoh, MA Atkinson, MR Christie, P Casali, PG Colman, R Gianani, RC Nayak, RJ Tuson, RL Sorenson, S Baekkeskov, S Baekkeskov, S Genovese, W Richter, W Richter, W Richter, WA Scherbaum   +19 more
core   +1 more source

Recent Perspectives on Phytochemical Profile, Pharmacological Activities, and Industrial Applications of Guava (Psidium guajava)

Food Safety and Health, EarlyView.
Psidium guajava leaves contain potent bioactive compounds like quercetin, myricetin, and triterpenoids that show antioxidant, antidiabetic, anti‐inflammatory, and anticancer effects. They act by modulating NF‐κB, PPARγ, and α‐glucosidase and by inducing apoptosis and cell cycle arrest.
Muhammad Waqar, Sehrish Jabbar, Qudrat Ullah, Farhang Hameed Awlqadr, Muhammad Tayyab Arshad, Md. Sakhawot Hossain, Sammra Maqsood, Ali Ikram, Ammar Ahmad Khan, Worawan Panpipat, Manat Chaijan   +10 more
wiley   +1 more source