Results 51 to 60 of about 21,603 (207)

One thousand faces of langerhans islets [PDF]

open access: yesInternational journal of pancreatology, 1999
Studies with different strains of Syrian hamsters and Syrian golden hamsters have revealed the remarkable potential of islet cells to undergo orthotopic and heterotopic metaplasia. The most common spontaneous change included the development of hepatocytes in aged and malnourished hamsters.
Pour, Parviz, Schmied, Bruno
openaire   +5 more sources

HTR1A a novel type 1 diabetes susceptibility gene on chromosome 5p13-q13. [PDF]

open access: yesPLoS ONE, 2012
We have previously performed a genome-wide linkage study in Scandinavian Type 1 diabetes (T1D) families. In the Swedish families, we detected suggestive linkage (LOD≤2.2) to the chromosome 5p13-q13 region.
Samina Asad   +20 more
doaj   +1 more source

In Vitro Leishmanicidal Efficacy of Synthesized Arylidene Analogues of Glitazone

open access: yesDrug Development Research, Volume 86, Issue 5, August 2025.
ABSTRACT Diabetes is a fast‐growing health issue in low‐ and middle‐income countries, with ~80% of diabetics living in the tropics and sub‐tropics. It is a deadly condition claiming the lives of millions of individuals annually, with no therapeutic treatment available to date. The management of diabetes is thus limited to symptomatic relief by glycemic
Janine Aucamp   +4 more
wiley   +1 more source

The Effects of Probiotics Consumption on Blood Pressure, Lipid Profile, Glycemic Indices, and Inflammatory Parameters in Overweight and Obese Adults: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
This systematic review and meta‐analysis of 26 randomized controlled trials involving 1755 overweight or obese adults demonstrated that probiotics provide small but statistically significant improvements in diastolic blood pressure, fasting glucose, insulin, total cholesterol, LDL cholesterol, triglycerides, and C‐reactive protein levels.
Safa Sefidgari‐Abrasi   +4 more
wiley   +1 more source

Congenital absence of islets of Langerhans. [PDF]

open access: yesArchives of Disease in Childhood, 1977
A small-for-dates male infant who developed acute metabolic acidosis shortly after birth had diabetes and died aged 40 hours. At necropsy there was an absence of any recognizable islets of Langerhans though lymphorecticular aggregates were found. This was the fourth child of healthy unrelated parents whose first child, also a male, died at 48 hours ...
J A Dodge, K M Laurence
openaire   +3 more sources

Constitutive nitric oxide synthase (cNOS) activity in Langerhans islets from streptozotocin diabetic rats

open access: yesBrazilian Journal of Medical and Biological Research, 1998
Nitric oxide synthase activity was measured in Langerhans islets isolated from control and streptozotocin diabetic rats. The activity of the enzyme was linear up to 150 µg of protein from control rats and was optimal at 0.1 µM calcium, when it was ...
T.M. Fonovich de Schroeder   +3 more
doaj   +1 more source

Anticancer Molecular Mechanisms of Epigallocatechin Gallate: An Updated Review on Clinical Trials

open access: yesFood Science &Nutrition, Volume 13, Issue 8, August 2025.
Epigallocatechin gallate (EGCG), a bioactive compound abundantly exists in green tea and grapes with strong antioxidant activity and anticancer potential is a suitable approach to reduce the cancer burden. The invitro and invivo anticancer studies of EGCG proved anticancer and anti‐tumor effect through modulation of cancer signaling pathways, reduction
Ahmad Mujtaba Noman   +13 more
wiley   +1 more source

Development of the Islets of Langerhans in Man [PDF]

open access: yesNature, 1961
VERY little has been published about the differentiation of the α and β cells in the development of the pancreatic islets in man. The only work since the introduction of the modern granule stains is that of Ferner and Stoeckenius1 (based on twelve fœtal pancreases), and Schultze Jena2 (based on six ...
openaire   +3 more sources

A conserved rule for pancreatic islet organization. [PDF]

open access: yesPLoS ONE, 2014
Morphogenesis, spontaneous formation of organism structure, is essential for life. In the pancreas, endocrine α, β, and δ cells are clustered to form islets of Langerhans, the critical micro-organ for glucose homeostasis.
Danh-Tai Hoang   +8 more
doaj   +1 more source

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

open access: yesDiabetes, Obesity and Metabolism, Volume 27, Issue S6, Page 28-39, August 2025.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio   +1 more
wiley   +1 more source

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