Results 51 to 60 of about 39,685 (253)

Collection of islets of Langerhans using an equilibrium method

open access: yesBioTechniques, 2013
Here we present a convenient method for easy hand selection of enzymatically isolated small tissues such as islets of Langerhans. Islets are continuously collected in a micropipette tip connected to a peristaltic pump.
Duk-Su Koh, Mark Moody, Junghyo Jo
doaj   +1 more source

The effect of ghrelin on Kiss-1 and KissR gene transcription and insulin secretion in rat islets of Langerhans and CRI-D2 cell line [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2017
Objective(s): Ghrelin is a peptide hormone that has been shown to have numerous central and peripheral effects. The central effects including GH secretion, food intake, and energy homeostasis are partly mediated by Kiss1- KissR signaling pathway. Ghrelin
Mandana Mahmoodzaeh Sagheb   +2 more
doaj   +1 more source

Rodent monocyte‐derived macrophages do not express CD163: Comparative analysis using macrophages from living boreoeutherians

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background CD163 is a scavenger receptor predominantly expressed on the surfaces of macrophages in various mammalian species and is a marker of anti‐inflammatory (M2‐like) macrophages. High density of CD163‐positive tumor‐associated macrophages (TAMs) is associated with worse prognosis in various patient tumors.
Yoichi Saito   +9 more
wiley   +1 more source

Modulation of endoglin expression in islets of langerhans by VEGF reveals a novel regulator of islet endothelial cell function [PDF]

open access: yes, 2016
BACKGROUND: Endoglin/CD105 is an auxiliary receptor for transforming growth factor-β with established roles in vascular remodelling. It has recently been shown that heterozygous endoglin deficiency in mice decreases insulin secretion in an animal model ...
Arthur, H   +7 more
core   +3 more sources

Effect of Ganoderma lucidum hydroalcoholic extract on insulin release in rat-isolated pancreatic islets [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2012
Objective: Ganoderma Lucidum (G. Lucidum) has been suggested to increase serum insulin level.This study was undertaken to investigateits direct effect on the islets of Langerhans.
Reza Shafiee-Nick   +3 more
doaj  

First application of three‐dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology

open access: yesAndrology, EarlyView.
Abstract Background Testicular tumors are among the most frequently diagnosed cancers in young men. The consequences of this diagnosis are orchiectomies, severely restricting fertility. For these young patients, a comprehensive diagnostics would be desirable, achieving a refined diagnosis and improved therapeutic patient stratification.
Diana Pinkert‐Leetsch   +6 more
wiley   +1 more source

Hypothalamically-Induced Insulin Release and its Potentiation During Oral and Intravenous Glucose Loads [PDF]

open access: yes, 1984
Male Wistar rats were provided with bilateral cannulas in the lateral hypothalamic area (LHA) and cannulas in the left and right jugular vein. Freely moving rats provided in this way with cannulas were infused with transmitters in the LHA and with ...
A.B. Steffens   +35 more
core   +4 more sources

Sex differences in the effects of maternal voluntary oral Cannabis consumption on the metabolic outcomes of high‐fat diet in adult offspring

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 11, Page 2354-2373, June 2025.
Sex differences in the effects of maternal voluntary editable Cannabis consumption on the metabolic phenotype of adult offspring on a high‐fat diet. Abstract Background and Purpose Given the recent rise in Cannabis legalisation, accessibility to Cannabis and consumption have increased during pregnancy. Therefore, there could be unintended developmental
Nada A. Sallam   +5 more
wiley   +1 more source

Variation in effectiveness of the NHS Diabetes Prevention Programme in people diagnosed with non‐diabetic hyperglycaemia by age, sex, BMI, and deprivation: A matched cohort analysis of 69,801 people

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims The NHS Diabetes Prevention Programme (DPP) is a behaviour‐change programme aimed at adults diagnosed with non‐diabetic hyperglycaemia (NDH), who are at higher risk of developing type 2 diabetes mellitus (Diabetes). This paper explores the heterogeneity in the effectiveness of the DPP by age, sex, BMI, and practice location deprivation ...
Rathi Ravindrarajah   +3 more
wiley   +1 more source

Type 1 diabetes risk factors, risk prediction and presymptomatic detection: Evidence and guidance for screening

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes is recognized as a chronic disease with a presymptomatic phase that does not require insulin therapy and a clinical phase where insulin treatment becomes necessary. The presymptomatic phase is characterized by the presence of autoantibodies targeting pancreatic islet beta cell antigens (islet autoantibodies).
Ezio Bonifacio   +1 more
wiley   +1 more source

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