Results 61 to 70 of about 39,685 (253)

Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement [PDF]

open access: yes, 1990
Nine patients who became diabetic after upper-abdominal exenteration and liver transplantation were given pancreatic islet-cell grafts obtained from the liver donor (eight cases), a third-party donor (one), or both (four). Two patients were diabetic when
Alejandro, R   +8 more
core   +1 more source

d‐amino acids: new functional insights

open access: yesThe FEBS Journal, EarlyView.
This review explores recent advances in understanding d‐amino acids (d‐AAs) and their pivotal roles across organisms, from plants to humans. d‐AAs have been implicated in key physiological processes, including cancer, inflammation, immune regulation, kidney disease, diabetes, and nervous system function.
Loredano Pollegioni   +5 more
wiley   +1 more source

In Vivo Imaging of Transplanted Pancreatic Islets

open access: yesFrontiers in Endocrinology, 2018
The beta-cells in the islets of Langerhans in the pancreas secrete insulin and play an important role in glucose homeostasis. Diabetes, characterized by hyperglycemia, results from an absolute or a relative deficiency of the pancreatic beta-cell mass ...
Donghee Kim   +3 more
doaj   +1 more source

The Islets of Langerhans in Relation to Diabetes [PDF]

open access: yesBiochemical Journal, 1907
The work recorded in the following paper was undertaken with a view to testing the hypothesis frequently brought forward that the islets of Langerhans of the pancreas yield an internal secretion whose function has some relation to the utilization of dextrose in the vertebrate organism. The primary cause of diabetes is, according to Macleod,1 the ' want
John Rennie, Thomas Fraser
openaire   +2 more sources

Tempo and mode of diversification of the red devil spiders (Araneae: Dysderidae) of the Canary Islands

open access: yesZoologica Scripta, Volume 54, Issue 3, Page 406-420, May 2025.
Abstract The study of adaptive radiations has shed light on our current understanding of evolution. However, previous studies examining the mode in which species diversified, how diversification rates varied, and how ecological specialisation affected these processes have found few different results across different taxa and geographic and ecological ...
Adrià Bellvert   +3 more
wiley   +1 more source

Moderate Intensity of Physical Exercise increased Β (Beta) Cell and Size of Langerhans Islets in Streptozotocin Induced Diabetes Mellitus Rats

open access: yesSurabaya Physical Medicine and Rehabilitation Journal, 2019
Background: The death of β cells Langerhans islets in Diabetes Mellitus (DM) can cause loss of Langerhans islet function and worsen the progression of DM. Physical exercise plays a major part in DM treatment.
Sarah M Nurdin   +2 more
doaj  

Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis

open access: yesNature Communications, 2022
How pancreatic islets of Langerhans are built during development is incompletely understood. Here the authors find that Synaptotagmin-13 mediates remodeling of cell-matrix adhesion to regulate endocrine cell egression and islet morphogenesis.
Mostafa Bakhti   +17 more
doaj   +1 more source

The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study

open access: yesJournal of Rawalpindi Medical College
Objective: This study explored the effect of simvastatin on the histomorphology of islets of Langerhans, glucose and insulin levels in rats. Study Design: The study was a one-year laboratory-based experimental control trial.
Abdullah Qamar   +5 more
doaj   +1 more source

Positive feedback loop between MAPK and aquaporin 7 regulates autophagy and apoptosis induced by palmitate in RIN‐m5f cells

open access: yesFEBS Open Bio, Volume 15, Issue 6, Page 972-984, June 2025.
T2DM is characterized by peripheral blood insulin resistance and progressive pancreatic β‐cell dysfunction. Here, we showed that AQP7, the only aquaglyceroporin protein, regulates autophagy and apoptosis in pancreatic β‐cells. We propose the existence of a positive feedback loop between MAPK signaling and AQP7 that regulates autophagy and apoptosis in ...
Maoqi Wang   +5 more
wiley   +1 more source

One thousand faces of langerhans islets [PDF]

open access: yesInternational journal of pancreatology, 1999
Studies with different strains of Syrian hamsters and Syrian golden hamsters have revealed the remarkable potential of islet cells to undergo orthotopic and heterotopic metaplasia. The most common spontaneous change included the development of hepatocytes in aged and malnourished hamsters.
Pour, Parviz, Schmied, Bruno
openaire   +5 more sources

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