Results 61 to 70 of about 39,022 (224)

Pancreas and islet cell transplantation [PDF]

, 2002
Currently, for the patient with type 1 diabetes, a definitive treatment without resorting to the use of exogenous insulin can be achieved only with pancreas or islet cell transplantation.
A.N. Balamurugan, Alexander, Allen, Amos, Barber, Barrou, Bartlett, Björk, Bonner-Weir, Brekke, Calne, Calne, Cameron, Cheung, Chow, Corry, Diem, Diem, DiLandro, Fontes, Giannoukakis, Giannoukakis, Gibson, Gliedman, Grey, Groth, Groth, Gu, Gupta, Harris, Hayek, Henry, Ilieva, Kelly, Kemp, Kendall, Kendall, Keymeulen, Kirk, Koike, Koike, Lacy, Lafferty, Lakey, Lillehei, London, Massimo Trucco, Mazariegos, Mintz, Murray, Najarian, Nghiem, Paraskevas, Petruzzo, Piehlmeier, Pipeleers-Marichal, Posselt, Prevost, Rajotte, Ramiya, Ramos, Ricordi, Rita Bottino, Robertson, Shapiro, Simeonovic, Solders, Sollinger, Sollinger, Sollinger, Soria, Ssobolew, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stone, Stratta, Stratta, Sutherland, Suzuki, Tchervenivanov, Terasaki, Thomas E. Starzl, Tyden, Tzakis, Yasunami   +94 more
core   +1 more source

Moderate Intensity of Physical Exercise increased Β (Beta) Cell and Size of Langerhans Islets in Streptozotocin Induced Diabetes Mellitus Rats

Surabaya Physical Medicine and Rehabilitation Journal, 2019
Background: The death of β cells Langerhans islets in Diabetes Mellitus (DM) can cause loss of Langerhans islet function and worsen the progression of DM. Physical exercise plays a major part in DM treatment.
Sarah M Nurdin, Sri Mardjiati Mei Wulan, Nuniek Nugraheni   +2 more
doaj  

The Effects Of Simvastatin On Islets Of Langerhans In The Pancreas Of Rats: A Histological And Biochemical Study

Journal of Rawalpindi Medical College
Objective: This study explored the effect of simvastatin on the histomorphology of islets of Langerhans, glucose and insulin levels in rats. Study Design: The study was a one-year laboratory-based experimental control trial.
Abdullah Qamar, Hammad Gul Khan, Hina Kundi, Ayesha Ali, Sumyyia Bashir, Tooba Khurshid   +5 more
doaj   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Role of YAP and TAZ in pancreatic ductal adenocarcinoma and in stellate cells associated with cancer and chronic pancreatitis. [PDF]

, 2015
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a fibrotic and inflammatory microenvironment that is formed primarily by activated, myofibroblast-like, stellate cells.
Dhall, Deepti, Greene, Mark I, Morvaridi, Susan, Pandol, Stephen J, Wang, Qiang   +4 more
core   +1 more source

An investigation of acute effects at various doses of malathion on glucose homeostasis and insulin resistance in rat liver, pancreas and serum [PDF]

, 2020
Objective. This study investigates acute effects of various doses of Malathion on glucose homeostasis and insulin resistance in rat. Methods. Rats were randomly divided into four groups of 6 animals each. Corn oil was given orally to Group 1.
Ekremoğlu, Murat, Pasaoğlu, Hatice, Pasaoğlu, Özge Tuğce, Severcan, Çınar, Şen, Bayram   +4 more
core   +3 more sources

An international consensus on screening and monitoring early‐stage type 1 diabetes: A roadmap to European implementation

Diabetes, Obesity and Metabolism, EarlyView.
Abstract Type 1 diabetes (T1D) is a chronic autoimmune disease that results in loss of insulin‐secreting pancreatic β‐cells in the islets of Langerhans. A diagnosis of T1D is typically associated with children and adolescents, yet half of all diagnoses of T1D are made in adults.
Sufyan Hussain, Timothy Tree, Chantal Mathieu, Tomasz Klupa, Anna‐Kaisa Tuomaala, Maartje de Wit, Olga Kordonouri, Katarina Braune, Jaivir Pall, Luis Castano, Rachel E. J. Besser, Júlia Galhardo, Francesca Ulivi, Emanuele Bosi, Uroš Bogdanovic, Coralie Alabert, Tadej Battelino   +16 more
wiley   +1 more source

Immunological characterization of chromogranins A and B and secretogranin II in the bovine pancreatic islet [PDF]

, 1987
Antisera against chromogranin A and B and secretogranin II were used for analysing the bovine pancreas by immunoblotting and immunohistochemistry. All three antigens were found in extracts of fetal pancreas by one dimensional immunoblotting. A comparison
A Iacangelo, AD Smith, BS Wilson, C Hagn, D Grube, D Grube, D Grube, DT O'Connor, DT O'Connor, DV Cohn, E El-Nady, FU Reiffen, FU Reiffen, G Falkensammer, G Falkensammer, G Rindi, H Blaschko, H Lassmann, H Winkler, HD Mayor, IM Varndell, JA Nolan, JC Hutton, K Tatemoto, KB Helle, KB Helle, L Kilpatrick, LA Sternberger, LE Eiden, M Ehrhart, M Ravazzola, P Rosa, PH O'Farell, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, R Fischer-Colbrie, RV Floyd, S Bonner-Weir, S Lenzen, UK Laemmli, UM Benedum, WB Huttner, WJ Smith, WN Burnette   +44 more
core   +1 more source

Pancreatic islet (of Langerhans) revisited.

Histology and histopathology, 2019
One hundred and fifty years ago, Paul Langerhans described what would come to be known as pancreatic 'islet of Langerhans'. Since then, we have accumulated knowledge about the pancreatic islet, the cells that exist there and the hormones secreted by these cells.
openaire   +3 more sources

In Vivo Imaging of Transplanted Pancreatic Islets

Frontiers in Endocrinology, 2018
The beta-cells in the islets of Langerhans in the pancreas secrete insulin and play an important role in glucose homeostasis. Diabetes, characterized by hyperglycemia, results from an absolute or a relative deficiency of the pancreatic beta-cell mass ...
Donghee Kim, Hee-Sook Jun, Hee-Sook Jun, Hee-Sook Jun   +3 more
doaj   +1 more source